Patents by Inventor Manami Okazaki

Manami Okazaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9855261
    Abstract: The purpose of the present invention is to provide a polymeric compound in which a camptothecin compound and an anti-cancer effect enhancer, particularly a PARP inhibitor, are bound to a single molecule, whereby it becomes possible to reduce the toxicity to normal cells and deliver and release the two components to an affected area with high efficiency to thereby improve the pharmacological efficacy of the two components. Provided is a polymeric compound represented by general formula (1).
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: January 2, 2018
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Keiichiro Yamamoto, Manami Okazaki
  • Publication number: 20150290185
    Abstract: The purpose of the present invention is to provide a polymeric compound in which a camptothecin compound and an anti-cancer effect enhancer, particularly a PARP inhibitor, are bound to a single molecule, whereby it becomes possible to reduce the toxicity to normal cells and deliver and release the two components to an affected area with high efficiency to thereby improve the pharmacological efficacy of the two components. Provided is a polymeric compound represented by general formula (1).
    Type: Application
    Filed: October 31, 2013
    Publication date: October 15, 2015
    Inventors: Keiichiro Yamamoto, Manami Okazaki
  • Patent number: 9018323
    Abstract: [Problem]To provide a novel polymer derivative of a cytidine metabolic antagonist which allows release of a medicament irrespective of enzymes of the living body and is expected to have high therapeutic effects.
    Type: Grant
    Filed: November 16, 2011
    Date of Patent: April 28, 2015
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Keiichirou Yamamoto, Manami Okazaki, Dai Kawamura
  • Publication number: 20130331517
    Abstract: [Problem] To provide a novel polymer derivative of a cytidine metabolic antagonist which allows release of a medicament irrespective of enzymes of the living body and is expected to have high therapeutic effects.
    Type: Application
    Filed: November 16, 2011
    Publication date: December 12, 2013
    Applicant: NIPPON KAYAKU KABUSHIKI KAISHA
    Inventors: Keiichirou Yamamoto, Manami Okazaki, Dai Kawamura