Abstract: In accordance with various embodiments of the present disclosure, a method for non-invasive medical imaging is provided. In some embodiments, the method comprises emitting light from a photonic integrated circuit scale dual frequency comb at a plurality of different wavelengths via a hand-held device directed at one or more bodily structures, detecting acoustic waves from thermo-elastic changes in two or more elements within the bodily structures exposed to the emitted light via three or more sensors in the hand-held device, the two or more elements comprising at least oxygenated blood and non-oxygenated blood, generating an optical absorption spectrum from the detected acoustic waves, identifying at least two of the two or more elements within the bodily structures exposed to the emitted light based on the optical absorption spectrum, and generating a three-dimensional image of one or more blood vessels based on the optical absorption spectrum.

Abstract: In accordance with various embodiments of the present disclosure, a device for non-invasive medical imaging is provided. In some embodiments, the device comprises a photonic integrated circuit scale dual frequency comb (DFC), a hand-held wand, and at least one processing element. The wand comprises at least one emission point for emitting light from the DFC at a plurality of different wavelengths and at least three sensors. The wand directs the emitted light at one or more bodily structures. The sensors are adapted to detect acoustic waves from thermo-elastic changes in one or more elements within the bodily structures. The processing element is for generating an optical absorption spectrum from the detected acoustic waves, identifying one or more elements within the bodily structures based on the optical absorption spectrum, and generating a three-dimensional image of the elements based on the optical absorption spectrum from the detected acoustic waves.

Abstract: In accordance with various embodiments of the present disclosure, a method for non-invasive cancer imaging is provided. In some embodiments, the method comprises emitting light from a photonic integrated circuit scale dual frequency comb at a plurality of different wavelengths via a hand-held device directed at one or more bodily structures having one or more tumors, one or more suspected tumors, and/or one or more potential tumor sites, detecting acoustic waves from thermo-elastic changes in two or more elements within the bodily structures via three or more sensors in the hand-held device, the two or more elements comprising at least oxygenated blood and non-oxygenated blood, generating an optical absorption spectrum from the detected acoustic waves, identifying at least two elements within the bodily structures based on the optical absorption spectrum, and generating a three-dimensional image of one or more blood vessels based on the optical absorption spectrum.