Patents by Inventor Manasses C. Fonteles

Manasses C. Fonteles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of inhibiting secretory effects caused by Cholera
    Patent number: 5929095
    Abstract: The administration of the PAF antagonists BN 52021 and SR 27417, in combination with cyclooxygenase antagonist indomethacin are disclosed as effective in inhibiting the secretory effects caused by Cholera toxin.
    Type: Grant
    Filed: June 17, 1997
    Date of Patent: July 27, 1999
    Assignee: UVA Patent Foundation
    Inventors: Richard L. Guerrant, Guodong D. Fang, Manasses C. Fonteles
  • Method of inhibiting secretory effects caused by cholera
    Patent number: 5639750
    Abstract: The invention relates to the treatment fluid secretion caused by Cholera toxin that can be blocked through the administration of PAF antagonists BN 52021 and SR 27417.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 17, 1997
    Assignee: University of Virginia Patent Foundation
    Inventors: Richard L. Guerrant, Guodong D. Fang, Manasses C. Fonteles
  • Method of treating clostridium difficile colitis and cholera
    Patent number: 5436239
    Abstract: The invention relates to the treatment of antibiotic associated colitis, typically due to Clostridium difficile using the Platelet Activating Factor antagonists WEB 2170, SR 27417 or BN 52021, or the cyclooxygenase antagonist indomethacin. The PAF antagonists BN 52021 and SR 27417 and the cyclooxygenase antagonist indomethacin were effective in inhibiting the secretory effects caused by C. difficile Toxin A and by Cholera toxin.
    Type: Grant
    Filed: April 1, 1993
    Date of Patent: July 25, 1995
    Assignee: The University of Virginia Patent Foundation
    Inventors: Richard L. Guerrant, Guodong Fang, Manasses C. Fonteles