Abstract: The present invention includes a method and system using dynamic pressure measurements for determining a presence, location, and size of a leak in a chamber of a body. The method includes sealing a plurality of ports of the chamber, pressurizing the chamber with a fluid, measuring a dynamic pressure at each of the plurality of ports, and analyzing the dynamic pressure measured at each of the plurality of ports to determine a presence, location, and/or size of the leak. The location of the leak can be determined by analyzing magnitude and/or phase values from a generated frequency response function matrix, interpolating between two of the plurality of ports, triangulating between three of the plurality of ports, and/or analyzing a rate and profile at which the pressure decays at each of the plurality of ports to determine the location of the leak.