Patents by Inventor Manel JUAN OTERO

Manel JUAN OTERO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CD19-SPECIFIC CHIMERIC ANTIGEN RECEPTOR T-CELL THERAPY
    Publication number: 20240398945
    Abstract: The present invention refers to a CD19-specific chimeric antigen receptor (CAR) T-cell therapy and to its use for treating CD19+ malignancies.
    Type: Application
    Filed: May 6, 2022
    Publication date: December 5, 2024
    Inventors: Manel JUAN OTERO, Álvaro URBANO ISPIZUA, Mariona PASCAL CAPDEVILA, Jordi YAGÜE RIBES, Julio DELGADO GONZÁLEZ, Jordi ESTEVE REYNER, María CASTELLÀ CASTELLÀ, Ana BORONAT BARADO
  • ANTI-CD19/ANTI-CD3 BISPECIFIC ANTIBODY, T CELLS SECRETING THE SAME, METHOD OF PREPARATION AND USE THEREOF
    Publication number: 20230087263
    Abstract: The present invention relates to a bispecific antibody comprising an anti-CD19 single-chain fragment variable and an anti-CD3 single-chain fragment variable. The present invention also relates to T cells secreting the bispecific antibody, method of preparation of T cells secreting the bispecific antibody and uses thereof in the treatment of a hematological malignancy selected from the group consisting of lymphoma, leukemia and myeloma.
    Type: Application
    Filed: February 16, 2021
    Publication date: March 23, 2023
    Inventors: Luis Manuel ÁLVAREZ VALLINA, Belén BLANCO DURANGO, Manel JUAN OTERO
  • CAR T-CELLS AGAINST BCMA FOR THE TREATMENT OF MULTIPLE MYELOMA
    Publication number: 20220267459
    Abstract: The present invention provides therapeutics for the treatment of Multiple myeloma. In particular, the present invention provides chimeric antigen receptor (CAR) T-cells that can target the B cell maturation antigen.
    Type: Application
    Filed: August 3, 2020
    Publication date: August 25, 2022
    Inventors: Beatriz MARTÍN ANTONIO, Álvaro URBANO ISPIZUA, Lorena PÉREZ AMILL, Guillermo SUÑE RODRIGUEZ, Manel JUAN OTERO