Patents by Inventor Manford K. Patterson, Jr.

Manford K. Patterson, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transglutaminase gene
    Patent number: 5726051
    Abstract: The present invention relates to a 1.9 kb cDNA and new tissue transglutaminase protein encoded thereby. The cDNA was obtained from reverse transcription of mRNA isolated from retinoic-acid treated HEL cells. The invention also relates to vectors and expression systems to produce the new tissue transglutaminase as well as the recombinantly-produced enzyme protein.
    Type: Grant
    Filed: May 23, 1994
    Date of Patent: March 10, 1998
    Assignee: Oklahoma Medical Research Foundation
    Inventors: Bassam M. Fraij, Paul J. Birckbichler, Manford K. Patterson, Jr., Robert A. Gonzales
  • Method for the detection of factor XIII in plasma
    Patent number: 5015588
    Abstract: An assay method for the detection of Factor XIII in plasma is disclosed in which a primary amine derivative of biotin such as preferably 5-(biotinamido) pentylamine is incubated with a glutamine substrate and activated Factor XIII (Factor XIIIa) to form a biotinylated product which may be measured by convention detection assays. In a preferred embodiment, the biotinylated product is bound to a well in a microtiter plate or other solid support and the product is measured by a colorimetric assay which may be read by an automated spectrophotometric plate reader.
    Type: Grant
    Filed: October 29, 1987
    Date of Patent: May 14, 1991
    Assignee: The Samuel Roberts Noble Foundation, Inc.
    Inventors: Kyung Lee, Manford K. Patterson, Jr., Paul J. Birckbichler