Abstract: In an exemplary embodiment at least one pair of oppositely adjustable clamping jaws are to be controlled. In the case of some examinations the cassette holder is not to be greater than the smallest x-ray film cassette to be clamped by it in order to avoid obstructions in the application of the clamped x-ray film cassette to the patient (e.g. axilla region or neck region). To this end, the disclosure provides that an adjustment handle, displaceable on the housing of the cassette holder, is coupled with a slide which is displaceable in the housing and connected with a clamping jaw, and that the latter slide is coupled with the one end of a two-arm lever whose other end is connected with a clamping jaw. Such a cassette holder is particularly suited for use in the case of x-ray examination apparatus.