Patents by Inventor Manfred Gloger

Manfred Gloger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilized sarcosine oxidase preparation
    Patent number: 4950609
    Abstract: The present invention provides a stabilized sarcosine oxidase preparation which contains creatineamidinohydrolase covalently bound to a water-soluble polysaccharide.
    Type: Grant
    Filed: March 27, 1986
    Date of Patent: August 21, 1990
    Assignee: Boehringer Mannheim GMBH
    Inventors: Wilhelm Tischer, Manfred Gloger, Josef Heinle
  • Process for the preparation of stereoisomers of 1-aminoalkylphosphonic and phosphinic acids
    Patent number: 4859602
    Abstract: The present invention provides a process for the preparation of the stereoisomers of 1-aminoalkylphosphonic acids and of 1-aminoalkylphosphinic acids by enzymatic resolution of their racemic N-acyl derivatives and subsequent deacylation, wherein the enzymatic resolution is carried out with penicillin G amidase.
    Type: Grant
    Filed: September 9, 1985
    Date of Patent: August 22, 1989
    Assignee: Boehringer Mannheim GmbH
    Inventors: Gerd Zimmermann, Josef Maier, Manfred Gloger
  • Process for obtaining D(+)-naproxen
    Patent number: 4857462
    Abstract: A process for obtaining D-2-(6-methoxy-2-naphthyl)-propionic acid from a mixture of D- and L-2-(6-methoxy-2-naphthyl)-propionic acid lower alkyl esters is provided by asymmetric hydrolysis of the L-ester with a microbial enzyme, separation of the 2-(6-methoxy-2-naphthyl)-propionic acid from the D-2-(6-methoxy-2-naphthyl)-propionic acid lower alkyl ester and saponification of the latter, wherein the saponification is carried out enzymatically with esterase from hog liver or from Pleurotus ostreatus.
    Type: Grant
    Filed: October 27, 1986
    Date of Patent: August 15, 1989
    Assignee: Boehringer Mannheim GmbH
    Inventors: Josef Maier, Manfred Gloger, Detlef V. Hoerschelmann, Jan Strejcek, Sebastian Heimerl
  • Method for the direct determination of the lipid content of blood beta-lipoproteins
    Patent number: 4569917
    Abstract: Method of direct determination of beta-lipoproteins in a blood sample containing pre-beta-lipoprotein, (VLDL) alpha-lipoprotein (HDL), and beta-lipoprotein (LDL), comprising mixing the blood plasma or serum of the blood sample with a solid, water-insoluble anion exchanger operable to retain the pre-beta-lipoprotein (VLDL) and the alpha-lipoprotein (HDL) to remove them from solution, separating the blood plasma or serum from the anion exchanger and thereafter determining the amount of beta-lipoprotein (LDL) remaining in solution.
    Type: Grant
    Filed: March 5, 1981
    Date of Patent: February 11, 1986
    Assignee: Boehringer Mannheim GmbH
    Inventors: Josef Maier, Manfred Gloger, Brigitte Draeger
  • Method for the determination of low density lipoprotein
    Patent number: 4474887
    Abstract: The present invention provides a process for the determination of the .beta.-lipoprotein fraction (LDL) in body fluids, especially in serum or plasma, wherein the LDL fraction is selectively precipitated from the sample by the addition of a polyvinyl sulphate with monovalent cations and then determined.The present invention also provides a reagent for the determination of the .beta.-lipoprotein fraction (LDL) in body fluids, especially in serum or plasma, wherein it contains polyvinyl sulphate.
    Type: Grant
    Filed: August 18, 1982
    Date of Patent: October 2, 1984
    Assignee: Boehringer Mannheim GmbH
    Inventors: Josef Maier, Manfred Gloger, Brigitte Drager
  • Soluble liver uricase with a process for the preparation thereof and with the use thereof
    Patent number: 4460683
    Abstract: The present invention provides liver uricase, wherein it is covalently bond to a water-soluble polysaccharide, polyacid anhydride, polyvinylpyrrolidone or acid anhydride as carrier substance and is still soluble at pH values below 6.The present invention also provides a process for the preparation of this liver uricase.
    Type: Grant
    Filed: July 2, 1982
    Date of Patent: July 17, 1984
    Assignee: Boehringer Mannheim GmbH
    Inventors: Manfred Gloger, Josef Heinle, Helmut Schlumberger