Patents by Inventor Manfred Koegl

Manfred Koegl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 6-amino-quinolinone compounds and derivatives as BCL6 inhibitors
    Patent number: 11001570
    Abstract: The present invention encompasses compounds of formula (I), wherein the groups R1 to R5, X, Y and W have the meanings given in the claims and specification, their use as inhibitors of BCL6, pharmaceutical compositions which contain compounds of this kind and their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: May 11, 2021
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Steffen Steurer, Georg Dahmann, Nina Kerres, Manfred Koegl
  • NEW 6-AMINO-QUINOLINONE COMPOUNDS AND DERIVATIVES AS BCL6 INHIBITORS
    Publication number: 20200071297
    Abstract: The present invention encompasses compounds of formula (I), wherein the groups R1 to R5, X, Y and W have the meanings given in the claims and specification, their use as inhibitors of BCL6, pharmaceutical compositions which contain compounds of this kind and their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases.
    Type: Application
    Filed: December 7, 2017
    Publication date: March 5, 2020
    Inventors: Steffen STEURER, Georg DAHMANN, Nina KERRES (Deceased), Manfred KOEGL
  • FXR NR1H4 nuclear receptor binding compounds
    Patent number: 7098336
    Abstract: The invention provides compounds according to the general formula (1) which bind to the NR1H4 receptor and act as agonists, antagonists or mixed agonists/antagonists of the NR1H4 receptor. The invention further provides methods of treating diseases and/or conditions through binding of the nuclear receptor by the compounds and the production of medicaments using the compounds.
    Type: Grant
    Filed: August 13, 2002
    Date of Patent: August 29, 2006
    Assignee: Phenex Pharmaceuticals AG
    Inventors: Ulrike Bauer, Zach Cheruvallath, Ulrich Deuschle, Elena Dneprovskaia, Tim Gahman, Kristina Giegrich, Ronnie Hanecak, Normand Hébert, John Kiely, Ingo Kober, Manfred Kögl, Harald Kranz, Claus Kremoser, Matthew Lee, Kerstin Otte, Carlton Sage, Manish Sud
  • NR1H4 nuclear receptor binding compounds
    Patent number: 7034046
    Abstract: The present invention relates to compounds according to the general formula (I) which bind to the nuclear receptor, NR1H4, and act as agonists and antagonists of the NR1H4 receptor. The invention further relates to the treatment of diseases and/or conditions through binding of the nuclear receptor by the compounds.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: April 25, 2006
    Assignee: Phenex Pharmaceuticals AG
    Inventors: Ulrike Bauer, Zach Cheruvallath, Ulrich Deuschle, Elena Dneprovskaia, Tim Gahman, Kristina Giegrich, Ronnie Hanecak, Normand Hébert, John Kiely, Ingo Kober, Manfred Kögl, Harald Kranz, Claus Kremoser, Matthew Lee, Kerstin Otte, Carlton Sage, Manish Sud
  • NR1H4 nuclear receptor binding compounds
    Patent number: 6974830
    Abstract: The present invention relates to compounds according to the general formula (I) which bind to the NR1H4 receptor and act as agonists of the NR1H4 receptor. The invention further relates to the treatment of diseases and/or conditions through binding of the nuclear receptor by the compounds and the production of medicaments using the compounds.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: December 13, 2005
    Assignee: Phenix Pharmaceuticals AG
    Inventors: Ulrike Bauer, Zach Cheruvallath, Ulrich Deuschle, Elena Dneprovskaia, Tim Gahman, Kristina Giegrich, Ronnie Hanecak, Normand Hébert, John Kiely, Ingo Kober, Manfred Kögl, Harald Kranz, Claus Kremoser, Matthew Lee, Kerstin Otte, Carlton Sage, Manish Sud
  • Novel 2-amino-4-quinazolinones and 2-amino-4-oxoquinazolones as LXR nuclear receptor binding compounds with partial agonistic properties
    Publication number: 20050261319
    Abstract: The present invention relates to compounds according to the general formulas (I) and/or (Ia), which bind to the LXR receptors and act as agonists and antagonists of the LXR receptors. The invention further relates to the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and the production of medicaments using said compounds.
    Type: Application
    Filed: March 9, 2005
    Publication date: November 24, 2005
    Inventors: Ulrich Deuschle, Ralph Loebbert, Beatrix Blume, Manfred Koegl, Claus Kremoser, Ingo Kober, Ulrike Bauer, Kristina Hermann, Michael Albers