Abstract: The invention relates to quinoline and isoquinoline derivatives of general formula I 1

Abstract: The present invention relates to non-steroidal progestins of the general formula (I) 1

Abstract: This invention describes the new, nonsteroidal gestagens of general formula I 1

Abstract: The invention relates to an extrusion head (10) for a blow molding machine for producing two-layered hollow plastic bodies, including one or more extruders, connected to the extrusion head housing (12), for supply of molten plastic melt. In particular when using different plastic materials of different viscosities, it is very important to create for both materials substantially the same rheological flow conditions when distributed across the circumference to form a tubular parison.

Abstract: This invention describes the new, nonsteroidal gestagens of general formula I in which A, B, Ar1, R1, R2 and R3 have the meanings that are indicated in more detail in the description. The new compounds show a very great affinity to the gestagen receptor. They can be used alone or in combination with estrogens in contraceptive preparations. In addition, they can be used for treating endometriosis. Together with estrogens, they can also be used in preparations for treating gynecological disorders, for treating premenstrual symptoms and for substitution therapy. Based on the androgenic action, they can also be used for male birth control, male HRT and hormone therapy and for treating andrological disease agents.

Abstract: T cells of a graft recipient are stimulated in-vitro by cells of a graft donor or by cells which express dominant MHC-molecules, while they are transduced with immuno-modulatory genes using gene transfer. Following the gene transfer the transduced T cells start to express immuno-modulatory genes. The gene transfer can be accomplished using retroviruses, other viral vector systems or liposomes. Due to the chosen set-up of the experiment, which leads to the generation and expansion of allospecific T cells, the T cells migrate, after the in-vivo application, specifically into the allogeneic graft as well as into the draining lymph nodes and are then able to express the immuno-modulatory genes there. Rejection of allogeneic grafts (cells, tissues, organs) can be successfully prevented, tolerance towards allogeneic grafts can be induced and maintained.

Abstract: The compound of formula 1 1

Abstract: A printer or copier includes a high speed monochrome or two color printer portion and a slower full color printer portion. Print job signals are divided into monochrome and color printed pages and sent to the corresponding printer portion. The printers, or a paper handling path between the printers, is controlled to assemble the printed pages into a predetermined sequence order.

Abstract: This invention describes the new, nonsteroidal gestagens of general formula I 1

Abstract: This invention describes the new, nonsteroidal gestagens of general formula I in which A, B, Ar, R1, R2 and R3 have the meanings that are indicated in more detail in the description. The new compounds show a very great affinity to the gestagen receptor. They can be used alone or in combination with estrogens in contraceptive preparations. In addition, they can be used for treating endometriosis. Together with estrogens, they can also be used in preparations for treating gynecological disorders, for treating premenstrual symptoms and for substitution therapy. Based on the androgenic action, they can also be used for male birth control, male HRT and hormone therapy and for treating andrological disease agents.

Abstract: This invention describes the use of the compounds of general formula I in which A, B, A, Ar, R1, R2 and R3 have the meaning that is indicated in more detail in the description, for the production of pharmaceutical agents with anti-inflammatory action. The compounds of general formula I show a clear dissociation between anti-inflammatory and metabolic action.

Abstract: A printer or copier includes a high speed monochrome or two color printer portion and a slower full color printer portion. Print job signals are divided into monochrome and color printed pages and sent to the corresponding printer portion. The printers, or a paper handling path between the printers, is controlled to assemble the printed pages into a predetermined sequence order.

Abstract: This invention describes the new, nonsteroidal gestagens of general formula I in which A, B, Ar, R1, R2 and R3 have the meanings that are indicated in more detail in the description. The new compounds show a very great affinity to the gestagen receptor. They can be used alone or in combination with estrogens in contraceptive preparations. In addition, they can be used for treating endometriosis. Together with estrogens, they can also be used in preparations for treating gynecological disorders, for treating premenstrual symptoms and for substitution therapy. Based on the androgenic action, they can also be used for male birth control, male HRT and hormone therapy and for treating andrological disease agents.

Abstract: A device for simultaneous application of a plurality of adhesive spot s to a substrate, having a metering apparatus for conveying a predetermined volume of adhesive to a plurality of applicator nozzles for the application of respectively one adhesive spot to the substrate. A distribution apparatus distributes the volume of adhesive conveyed by the metering, device to the applicator nozzles. A warming medium is heated in a warning apparatus for heating the adhesive to a temperature desired for manipulation. The metering apparatus and the distribution apparatus are connected with each other by a conveying line containing an adhesive conduit. Feed lines with adhesive conduits lead from the distribution apparatus to the applicator nozzles, wherein a closed loop of the warming medium is formed, starting at the warming apparatus, and routed via the distribution apparatus and the feed lines to the applicator nozzles, and is returned via the feed lines and the distribution apparatus to the warming apparatus.

Abstract: In order to obtain an optimal application of viscous material, such as an adhesive or a sealing agent. The process and apparatus combines the proportional metering device and the outlet valve to form a constructional unit. A static mixing tube is integrated into the filling opening. The feed pipe is partially tempered and therefore maintains the viscous material situated in the feed pipe at a constant temperature.

Abstract: The invention relates to a refillable container that implements the first-in/first-out principle for highly viscous media, with an interior chamber delimited by a bottom and side walls and with a removal channel formed in the bottom of the container and with a follower plate placed loosely in the interior of the container, said plate sealing off the interior chamber and being sealed off from the side walls of the container, said plate further being movable upward or downward under the influence of pressure in the interior of the container, with a filling chamber for the medium being capable of being isolated from the interior chamber between the follower plate and the bottom of the container, and with a filling channel for loading the medium into the filling chamber and with a vent channel for venting the filling chamber running through the follower plate, and with the filling channel and air supply channel each being connectable with a line brought out of the container and being sealable as well.

Abstract: The ink jet print device has a multiplicity of plug-in type printheads (12) mounted on support plates (23). The support plates can be replaced and interchanged without difficulty by an operator. To this end, the print device is divided into a lower part and the actual printheads (12) such that, when the heads (12) are plugged in, the necessary mechanical, electrical, and hydraulic connections (27, 28, 29, 31, 26, 41, 33) between the heads (12) and the lower part of the print device are all established. Guide and locking means are used to ensure that the plugged-in heads are exactly positioned and held in place. The sockets for the individual heads (12) are each of identical design so that the simple replacement concept permits any printheads to be used for color printing and graphics and for printing with different droplet sizes.

Abstract: The invention relates to a storage head for a blow moulding machine for discontinuous manufacture of multi-layer co-extruded and blow-moulded hollow bodies made of thermoplastic. To improve the product quality and to increase the throughput, each distributor element is designed as a spiral channel distributor (20) which distributes the individual molten plastic streams uniformly at the periphery. The ejector (14) consists of at least two concentric tubular pieces (42, 44) and the peripherally distributed plastic flows from the ejector (14) through an annular gap (46) into the storage space (16) in the storage head housing (10) below the ejector.

Abstract: A method for driving printing elements of a dot matrix printer provides that the matrix dots to be printed are to be thinned out without any thin lines, in particular steeply inclined thin lines, being lost. To this end, the columns of the matrix are considered to be arranged next to each other in pairs, and before the matrix dots in each line (Z) of the matrix are thinned out, a matrix dot is placed before or after a matrix dot used initially to create the character, so that both matrix dots belonging to a pair of columns (SP1, SP5) are covered by a line (Z). During the subsequent thinning out, the lines are printed sufficiently well and clearly. The process is intended for use in dot matrix printers.

Abstract: The invention relates to a storage head for a blow moulding machine for discontinuous manufacture of multi-layer co-extruded and blow-moulded hollow bodies made of thermoplastic. To improve the product quality and to increase the throughput, each distributor element is designed as a spiral channel distributor (20) which distributes the individual molten plastic streams uniformly at the periphery. The ejector (14) consists of at least two concentric tubular pieces (42, 44) and the peripherally distributed plastic flows from the ejector (14) through an annular gap (46) into the storage space (16) in the storage head housing (10) below the ejector.