Patents by Inventor Manfred Probst

Manfred Probst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4386031
    Abstract: The present invention refers to N-Benzoyl-.omega.
    Type: Grant
    Filed: November 6, 1981
    Date of Patent: May 31, 1983
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Gerd Hilboll, Hans-Heiner Lautenschlager, Brigitte Stoll, Manfred Probst
  • Patent number: 4377695
    Abstract: The present invention refers to new .omega.-(2-oxo-benzazolinyl)-alkanoic acids as well as salts and esters thereof having the general formula I ##STR1## and having antiinflammatory, analgesic and antithrombotic activity.
    Type: Grant
    Filed: November 6, 1981
    Date of Patent: March 22, 1983
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Hans-Heiner Lautenschlager, Hans Betzing, Brigitte Stoll, Manfred Probst
  • Patent number: 4358442
    Abstract: The present invention is directed to a new rosmarinic acid-phospholipide-complex product containing rosmarinic acid and the phospholipide in a molar ratio of 1:2. The invention is further directed to a process for producing the same and to pharmaceutical preparations containing the same.
    Type: Grant
    Filed: December 11, 1980
    Date of Patent: November 9, 1982
    Assignee: Nattermann & Cie GmbH
    Inventors: Ferdinand Wirtz-Peitz, Manfred Probst, Johannes Winkelmann
  • Patent number: 4349684
    Abstract: The present invention refers to N-substituted .omega.-(2-oxo-4-imidazolin-1-yl) alcanoic acids as well as salts and esters thereof having the general formula I ##STR1## The compounds are useful, for example, as antiallergics, antiasthmatics, etc.
    Type: Grant
    Filed: November 6, 1981
    Date of Patent: September 14, 1982
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Hans-Heiner Lautenschlager, Hans Betzing, Brigitte Stoll, Manfred Probst
  • Patent number: 4349686
    Abstract: The present invention refers to new 5-(N-Alkyl-N-acyl-amino)-thiophen-2-carboxylic acid derivatives having the general formula I ##STR1##
    Type: Grant
    Filed: November 12, 1981
    Date of Patent: September 14, 1982
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Hans-Heiner Lautenschlager, Hans Betzing, Johannes Winkelmann, Manfred Probst, Brigitte Stoll
  • Patent number: 4309407
    Abstract: The invention provides novel .omega.-(5-alkenylthien-2-yl)alkanecarboxylic acids and their functional derivatives having the formula ##STR1## wherein n is an integer from 1 to 9, inclusive; R.sup.1 is H and R.sup.2 is --OH, or R.sup.1 and R.sup.2 together with the wavy lines represent a keto group; and R.sup.3 is H, C.sub.1 -C.sub.6 straight or branched-chain saturated hydrocarbon, or a pharmaceutically acceptable alkali cation. The 3-oxoalkenyl-substituted compounds of formula (I) are prepared by a Wittig-Horner reaction using a 2-oxoheptylphosphonic acid dialkyl ester and an aldehyde of the formula ##STR2## as starting materials, while the 3-hydroxyalkenyl-substituted compounds are obtained by reduction of the corresponding 3-oxoalkenyl compounds. The esters of formula (I) can also be readily converted to the corresponding acids and salts of formula (I).
    Type: Grant
    Filed: November 12, 1980
    Date of Patent: January 5, 1982
    Assignee: A. Nattermann & Cie. GmbH
    Inventors: Hans-Heiner Lautenschlager, Hans Betzing, Johannes Winkelmann, Manfred Probst