Abstract: A process for producing a tissue transplant construct for reconstructing a human or animal organ. The process may include the steps of: (a) isolation and two-dimensional cultivation of organ-specific tissue cells; (b) application of the organ-specific tissue cells to a biocompatible, collagen-containing membrane; and, (c) cultivation of the organ-specific tissue cells on the membrane with biochemical and mechanical stimulation of the organ-specific tissue cells. Tissue transplant constructs and methods for using tissue transplant constructs are also taught.

Abstract: The invention relates to a tissue transplant construct for the reconstruction of a human or animal organ. Here said tissue transplant construct is intended to comprise (a) a biocompatible acellular membrane and (b) microvascular endothelial cells which penetrate the membrane, wherein microvascular structures of microvascular endothelial cells are formed within the membrane.

Abstract: A synthetic fiber cable has the strands of a strand layer mutually spaced apart. With the mutual spacing, the strands of the outer strand layer can move radially in the direction of the cable center and exert a radial pressure on the strands of the first inner strand layer. The radial pressure is passed on from the strands of the first inner strand layer to the strands of the second inner strand layer. The radial pressure is passed on from the strands of the second inner strand layer to the core strand. The radial pressure increases inwardly from strand layer to strand layer. The soft cable sheathing does not act as a support between the strands in circumferential direction.

Abstract: In an elevator installation, an apparatus and a method use a support end connection for fastening a support device to an elevator car, a counterweight and/or a building. The support device has at least one cable or cable strand enclosed by a cable casing and is held in a wedge pocket by a wedge. The cable casing is formed of thermoplastic material or an elastomer and the cable or the cable strand is glued to, fused together with or mechanically connected with the cable casing in the region of the support end connection. A friction force transmitted from the support end connection to the cable casing can then be directly passed on to the load-bearing core of the support device, to the cables or to the cable strands. The tolerable tension force in the support device is increased. The support device is preferably a multiple cable.

Abstract: The invention relates to a tissue transplant construct for the reconstruction of a human or animal organ, where the tissue transplant construct comprises: a) a biologically compatible, collagen-containing membrane, and b) one or more layers of organ-specific tissue cells on the membrane, and where the outermost layer of the organ-specific tissue cells is a layer of terminally differentiated organ-specific tissue cells.

Abstract: A synthetic fiber cable has the strands of a strand layer mutually spaced apart. With the mutual spacing, the strands of the outer strand layer can move radially in the direction of the cable center and exert a radial pressure on the strands of the first inner strand layer. The radial pressure is passed on from the strands of the first inner strand layer to the strands of the second inner strand layer. The radial pressure is passed on from the strands of the second inner strand layer to the core strand. The radial pressure increases inwardly from strand layer to strand layer. The soft cable sheathing does not act as a support between the strands in circumferential direction.

Abstract: A supporting and drive belt including a belt body or sheathing which encloses tensile carriers. The running surface of the belt can be flat and parallel to the belt back or have trapezium-shaped or semicircular ribs and grooves, wherein the profile of a drive pulley or of a deflecting pulley is approximately complementary to the running surface of the belt. One or more tensile carriers are provided for each rib, wherein the tensile carriers are laid or stranded alternately in the “Z” direction and the “S” direction.

Abstract: In an elevator installation, an apparatus and a method use a support end connection for fastening a support device to an elevator car, a counterweight and/or a building. The support device has at least one cable or cable strand enclosed by a cable casing and is held in a wedge pocket by a wedge. The cable casing is formed of thermoplastic material or an elastomer and the cable or the cable strand is glued to, fused together with or mechanically connected with the cable casing in the region of the support end connection. A friction force transmitted from the support end connection to the cable casing can then be directly passed on to the load-bearing core of the support device, to the cables or to the cable strands. The tolerable tension force in the support device is increased. The support device is preferably a multiple cable.

Abstract: The present invention relates to oligonucleotides directed against a survivin gene and variants thereof and to the use of said oligonucleotides in the diagnosis, prophylaxis, reduction and follow-up of diseases associated with cell growth, differentiation and/or division, such as tumor diseases.

Abstract: In an elevator installation, an apparatus and a method use a support end connection for fastening a support device to an elevator car, a counterweight and/or a building. The support device has at least one cable or cable strand enclosed by a cable casing and is held in a wedge pocket by a wedge. The cable casing is formed of thermoplastic material or an elastomer and at least one of a region of the wedge or the wedge pocket is provided with a longitudinal wedge groove and a region of the wedge, of the wedge pocket or the cable casing has a reduced coefficient of friction. The support device is preferably a multiple cable.

Abstract: A process for producing a tissue transplant construct for reconstructing a human or animal organ. The process may include the steps of: (a) isolation and two-dimensional cultivation of organ-specific tissue cells; (b) application of the organ-specific tissue cells to a biocompatible, collagen-containing membrane; and, (c) cultivation of the organ-specific tissue cells on the membrane with biochemical and mechanical stimulation of the organ-specific tissue cells. Tissue transplant constructs and methods for using tissue transplant constructs are also taught.

Abstract: The present invention relates to polynucleotides directed towards a gene of a catalytic subunit of human telomerase, as well as to the use of said polynucleotides for the diagnosis, prophylaxis, reduction and follow-up of diseases associated with cell growth, differentiation and/or division, such as tumor diseases.

Abstract: The invention relates to a method for detecting increased susceptibility to tumours by specifically detecting a polymorphism in the position 354 A ? G in the exon 12 of the human murine double minute-2 (MDM2) gene. Said polymorphism represents a hereditary marker for increased risk of cancer in humans. The invention also relates to the use of said tumour susceptibility marker for developing in vitro and in vivo test systems which integrate said markers, in a specific manner, into diagnostic, prognostic and possibly therapeutic methods.

Abstract: A printing couple in a printing machine is comprised of at least three cylinders, a forme cylinder, a transfer cylinder and a counter-pressure cylinder. The counter-pressure cylinder forms a printing location or point in cooperation with the transfer cylinder. The transfer cylinder is mounted in at least one lever which can be pivoted about an eccentrically pivoting axis in relation to the rotational axis of the forme cylinder. When the three cylinders are in a print position, a connecting plane through the axis of rotation of the forme cylinder and the pivoting axis of the lever forms an angle of between 25° and 65° with a plane through the axis of rotation of the cylinder forming the printing point.

Abstract: The invention relates to a procedure for quantitatively determining viral or bacterial particles having a cholesterol-containing envelope, wherein the viral particles under a fluorescence microscope.

Abstract: The invention relates to a method of improving the primary energy metabolism of mammalian cell lines, in which by means of genetic engineering a structural gene for a cytoplasmic yeast pyruvate carboxylase is inserted into the mammalian cells and expressed.

Abstract: The invention relates to a procedure for quantitatively determining viral particles having a cholesterol-containing envelope, wherein the viral particles are stained with the fluorescent dye filipin and the number of viral particles is determined by counting the fluorescent particles under a fluorescence microscope.

Abstract: The invention relates to a method of improving the primary energy metabolism of mammalian cell lines, in which by means of genetic engineering a structural gene for a cytoplasmic yeast pyruvate carboxylase is inserted into the mammalian cells and expressed.

Abstract: The invention relates to a method of improving the primary energy metabolism of mammalian cell lines, in which by means of genetic engineering a structural gene for a cytoplasmic yeast pyruvate carboxylase is inserted into the mammalian cells and expressed.

Abstract: Multicistronic expression units allow the equimolar expression of the genes located in the corresponding cistrons. These expression units are particularly suitable for the recombinant production of proteins composed of two or more polypeptide subunits.