Patents by Inventor Mangala Rao

Mangala Rao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Truncated HIV envelope proteins (ENV), methods and compositions related thereto
    Patent number: 10081658
    Abstract: The instant application provides methods and related compositions pertaining to novel HIV envelope proteins. In some embodiments, the invention relates to methods and compositions for the preparation, production, and administration of isolated novel HIV envelope nucleic acid and protein sequences suitable, for example, as vaccines against HIV.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: September 25, 2018
    Assignees: Advanced BioScience Laboratories, Inc., The United States of America as Represented by the Secretary of the Army, The Henry M. Jackson Foundation for the Advancement of Military Medicines, Inc.
    Inventors: Vaniambadi Kalyanaraman, Stephen Whitney, Thomas C. VanCott, Victoria Polonis, Carl Alving, Gary R. Matyas, Mangala Rao, Mary Marovich, Francine McCutchan, Sodsai Tovanabutra, Eric Sanders-Buell
  • METHODS FOR ENHANCING THE IMMUNOSTIMULATION POTENCY OF ALUMINUM SALT-ABSORBED VACCINES
    Publication number: 20170165358
    Abstract: Provided herein are (1) a method of mixing an aluminum salt-adsorbed immunogen with a monophosphoryl lipid A (MPLA)-containing liposome (L(MPLA)), and (2) the resulting immunogenic composition. The resulting immunogenic composition has an enhanced immunostimulation potency compared with either a composition comprising the uncapsulated immunogen mixed with the L(MPLA) or the aluminum salt-adsorbed immunogen alone.
    Type: Application
    Filed: July 9, 2014
    Publication date: June 15, 2017
    Inventors: Carl R. ALVING, Jerome H. KIM, Mangala RAO
  • TRUNCATED HIV ENVELOPE PROTEINS (ENV), METHODS AND COMPOSITIONS RELATED THERETO
    Publication number: 20140220107
    Abstract: The instant application provides methods and related compositions pertaining to novel HIV envelope proteins. In some embodiments, the invention relates to methods and compositions for the preparation, production, and administration of isolated novel HIV envelope nucleic acid and protein sequences suitable, for example, as vaccines against HIV.
    Type: Application
    Filed: April 25, 2012
    Publication date: August 7, 2014
    Applicants: ADVANCED BIOSCIENCE LABORATORIES, INC., HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, THE GOVERNMENT OF THE USA, AS REPRESENTED BY THE SECRETARY
    Inventors: Vaniambadi Kalyanaraman, Stephen Whitney, Thomas C. Vancott, Victoria Polonis, Carl Alving, Gary R. Matyas, Mangala Rao, Mary Marovich, Francine McCutchan, Sodsai Tovanabutra, Eric Sanders-Buell
  • Detection of human antibodies to squalene in serum
    Patent number: 7824864
    Abstract: The invention is a method and assay for detecting human squalene antibodies in sera or plasma using a blocking agent of ?0.5% casein in a phosphate buffered saline (PBS) solution.
    Type: Grant
    Filed: January 7, 2005
    Date of Patent: November 2, 2010
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Carl R Alving, Gary R Matyas, Nabila M Wassef, Mangala Rao
  • Detection of antibodies to squalene in serum
    Patent number: 7270964
    Abstract: The invention is a method for detecting squalene in sera.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: September 18, 2007
    Assignee: United States of America as Represented by the Secretary of the Army
    Inventors: Carl R Alving, Gary R Matyas, Nabila M Wassef, Mangala Rao
  • Detection of human antibodies to squalene in serum
    Publication number: 20060160160
    Abstract: The invention is a method and assay for detecting human squalene antibodies in sera or plasma using a blocking agent of ?0.5% casein in a phosphate buffered saline (PBS) solution.
    Type: Application
    Filed: January 7, 2005
    Publication date: July 20, 2006
    Inventors: Carl Alving, Gary Matyas, Nabila Wassef, Mangala Rao
  • Transcutaneous and/or transdermal transport of materials
    Publication number: 20050281789
    Abstract: The invention relates to transcutaneous and/or transdermal transport of materials, such as antigens, drugs, drugs, nucleic acids, (e.g., DNA and RNA), proteins, other therapeutic agents, dyes, and the like, into the skin and/or the body. The material is transported transcutaneously and/or transdermally using an antigen presenting cell (APC) by applying the APC and the material on to the surface of the skin.
    Type: Application
    Filed: May 20, 2005
    Publication date: December 22, 2005
    Inventors: Mangala Rao, Carl Alving, Kristina Peachman, Stephen Rothwell
  • Detection of antibodies to squalene in serum
    Patent number: 6900025
    Abstract: The invention is a method for detecting squalene in sera.
    Type: Grant
    Filed: May 18, 2001
    Date of Patent: May 31, 2005
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Carl R. Alving, Gary R. Matyas, Nabila M. Wassef, Mangala Rao
  • Detection of antibodies to squalene in serum
    Publication number: 20040248224
    Abstract: The invention is a method for detecting squalene in sera.
    Type: Application
    Filed: July 9, 2004
    Publication date: December 9, 2004
    Inventors: Carl R. Alving, Gary R. Matyas, Nabila M. Wassef, Mangala Rao
  • Detection of antibodies to squalene in serum
    Publication number: 20020022241
    Abstract: The invention is a method for detecting squalene in sera.
    Type: Application
    Filed: May 18, 2001
    Publication date: February 21, 2002
    Inventors: Carl R. Alving, Gary R. Matyas, Nabila M. Wassef, Mangala Rao