Patents by Inventor Mani SALARIAN

Mani SALARIAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds For Molecular Imaging of Collagen Turnover and Methods Using Same
    Publication number: 20240298987
    Abstract: In one aspect, the present disclosure relates to an imaging agent comprising a detectable moiety covalently bound or coordinated to a “Moiety A” selected from a peptide, a chelator, or an organic compound comprising a leaving atom or a leaving group that can be substituted with a radioisotope. “Moiety A” is covalently bound to a flexible linker which is further covalently bound to a polypeptide of between 2 and 20 glycine-proline-hydroxyproline repeats. In certain embodiments, the detectable moiety comprises a radioisotope or metal. In another aspect, the disclosure relates to a method of using the imaging agents of the present disclosure to detect collagen turnover in a subject.
    Type: Application
    Filed: June 22, 2022
    Publication date: September 12, 2024
    Inventors: Mehran Sadeghi, Mani Salarian, Kiran Gona, Jakub Toczek
  • CONTRAST AGENTS, METHODS FOR PREPARING CONTRAST AGENTS, AND METHODS OF IMAGING
    Publication number: 20240082434
    Abstract: Embodiments of the present disclosure provide for contrast agents, methods of making contrast agents, and methods of using contrast agents, and the like.
    Type: Application
    Filed: July 3, 2023
    Publication date: March 14, 2024
    Inventors: Jenny Jie YANG, Zhiren LIU, Jie JIANG, Shenghui XUE, Jinjuan QIAO, Mani SALARIAN
  • Contrast agents, methods for preparing contrast agents, and methods of imaging
    Patent number: 11738098
    Abstract: Embodiments of the present disclosure provide for contrast agents, methods of making contrast agents, and methods of using contrast agents, and the like.
    Type: Grant
    Filed: October 12, 2020
    Date of Patent: August 29, 2023
    Assignee: Georgia State University Research Foundation, Inc.
    Inventors: Jenny Jie Yang, Zhiren Liu, Jie Jiang, Shenghui Xue, Jinjuan Qiao, Mani Salarian
  • TARGETED PROTEIN CONTRAST AGENTS, METHODS OF MAKING, AND USES THEREOF
    Publication number: 20230057249
    Abstract: Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent.
    Type: Application
    Filed: August 11, 2022
    Publication date: February 23, 2023
    Inventors: Jenny Jie Yang, Fan Pu, Shenghui Xue, Jingjuan Qiao, Shanshan Tan, Mani Salarian
  • Targeted protein contrast agents, methods of making, and uses thereof
    Patent number: 11426471
    Abstract: Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: August 30, 2022
    Assignee: Georgia State University Research Foundation, Inc.
    Inventors: Jenny Jie Yang, Fan Pu, Shenghui Xue, Jingjuan Qiao, Shanshan Tan, Mani Salarian
  • Targeted protein contrast agents, methods of making, and uses thereof
    Patent number: 11419954
    Abstract: Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: August 23, 2022
    Assignee: Georgia State University Research Foundation, Inc.
    Inventors: Jenny Jie Yang, Fan Pu, Shenghui Xue, Jingjuan Qiao, Shanshan Tan, Mani Salarian
  • TARGETED PROTEIN CONTRAST AGENTS, METHODS OF MAKING, AND USES THEREOF
    Publication number: 20210038746
    Abstract: Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent.
    Type: Application
    Filed: September 9, 2020
    Publication date: February 11, 2021
    Inventors: Jenny Jie YANG, Fan PU, Shenghui XUE, Jingjuan QIAO, Shanshan TAN, Mani SALARIAN
  • CONTRAST AGENTS, METHODS FOR PREPARING CONTRAST AGENTS, AND METHODS OF IMAGING
    Publication number: 20210038745
    Abstract: Embodiments of the present disclosure provide for contrast agents, methods of making contrast agents, and methods of using contrast agents, and the like.
    Type: Application
    Filed: October 12, 2020
    Publication date: February 11, 2021
    Inventors: Jenny Jie YANG, Zhiren LIU, Jie JANG, Shenghui XUE, Jinjuan QIAO, Mani SALARIAN
  • TARGETED PROTEIN CONTRAST AGENTS, METHODS OF MAKING, AND USES THEREOF
    Publication number: 20200397925
    Abstract: Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent.
    Type: Application
    Filed: September 9, 2020
    Publication date: December 24, 2020
    Inventors: Jenny Jie YANG, Fan PU, Shenghui XUE, Jingjuan QIAO, Shanshan TAN, Mani SALARIAN
  • Contrast agents, methods for preparing contrast agents, and methods of imaging
    Patent number: 10849993
    Abstract: Embodiments of the present disclosure provide for contrast agents, methods of making contrast agents, and methods of using contrast agents, and the like.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: December 1, 2020
    Assignee: GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Jenny Jie Yang, Zhiren Liu, Jie Jiang, Shenghui Xue, Jinjuan Qiao, Mani Salarian
  • Targeted protein contrast agents, methods of making, and uses thereof
    Patent number: 10814020
    Abstract: Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: October 27, 2020
    Assignee: GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Jenny Jie Yang, Fan Pu, Shenghui Xue, Jingjuan Qiao, Mani Salarian, Shanshan Tan
  • TARGETED PROTEIN CONTRAST AGENTS, METHODS OF MAKING, AND USES THEREOF
    Publication number: 20180280544
    Abstract: Provided herein are protein contrast agents and targeted protein contrast agents, formulations thereof, and methods of use, including but not limited to, as a magnetic resonance imaging contrast agent.
    Type: Application
    Filed: May 11, 2016
    Publication date: October 4, 2018
    Inventors: Jenny Jie YANG, Fan PU, Shenguhi XUE, Jingjuan QIAO, Mani SALARIAN