Abstract: Provided are multiplexed methods for characterizing binding of a test compound to different receptor target molecules using mass spectroscopy techniques. The methods employ receptor molecules that have different functions or found in different tissues, such as cerebral cortex, cerebellum, ventricular and hepatic membrane preparations. The methods enable determination of undesirable off-target binding of a test compound. The methods comprise incubation of a heterologous mixture of different receptor target molecules with ligands (known binders), and a test compound. Various wells contain different amounts of molecules for use in construction of concentration curves. Next, unbound ligands are separated from the well contents. Next, ligands that were bound to the receptors are separated. An LC/ESI-MS/MS method may be used to reduce irrelevant mass spectroscopy peaks.

Abstract: A composition for protecting and/or preserving cells, tissues or organs, includes at least one cyclodextrin, preferably closely combined with an antioxidant. A process for producing this composition and its uses are also disclosed.

Abstract: The present invention relates to a reaction medium for identifying/detecting microorganisms, that comprises at least one active molecule encapsulated in a cyclodextrin.

Abstract: The object of the invention is a composition for protecting and/or preserving cells, tissues or organs, characterized in that it comprises at least one cyclodextrin, preferably closely combined with an antioxidant. The invention also relates to a process for producing this composition and its uses.