Patents by Inventor Manish Shanker

Manish Shanker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods involving MDA-7 for the treatment of cancer
    Publication number: 20070009484
    Abstract: The present invention concerns methods and compositions involving MDA-7 protein or an MDA-7-encoding nucleic acid in combination with either 1) a COX-2 selective inhibitor, such as celecoxib, 2) an Hsp90 inhibitor, such as geldanamycin, or a geldanamycin derivative or analog, 3) a vitamin E compound, for the treatment of cancer, 4) a TNF, such as TNF-alpha, 5) a VEGF inhibitor, or 6) an inhibitor of IL-10. In certain examples, a treatment for breast cancer is provided. In other examples a treatment for lung cancer is provided. Such examples involve, in some cases, an adenovirus vector that expresses MDA-7 protein.
    Type: Application
    Filed: February 8, 2006
    Publication date: January 11, 2007
    Inventors: Kelly Hunt, Young-Jin Suh, Stephen Swisher, Abujiang Pataer, Rajagopal Ramesh, Manish Shanker