Abstract: Provided herein are methods and compositions for treating cancer in an individual comprising administering to the individual an effective amount of at least one immune checkpoint inhibitor and a chimeric CD 154 polypeptide. Also provided herein are methods of enhanced immune function.

Abstract: An online system uses a model to determine affinities of users for geographical locations. Using the affinities, which may indicate travel-related preferences of the users, the online system may customize content items to include content captured by client devices of other users of the online system. For example, the online system presents to a particular user a content item including a photo or video of a geographical location captured by a camera of a client device of another user who is connected to the particular user. The model may implement, for example, collaborative filtering or other machine learning techniques to determine commonalities between users' travel affinities. Additionally, the model may determine latent properties or temporal trends of user preferences based on training data including historical actions performed on the online system or social data. The model may also classify different types of geographical locations.

Abstract: An online system provides navigation information customized using travel preferences of users. The online system receives actions performed by users that may indicate their geographical locations of interest. The online system may use a model to predict a user's level of interest in destination geographical locations. The online system generates navigation information or travel information that describes routes from origin geographical locations of users to destination geographical locations to which the users are likely to travel. The online system transmits the navigation information to client devices for presentation as personalized or dynamically-created content items to users. The online system may generate navigation information using catalogs describing routes between geographical locations. For instance, the catalog indicates a vehicle for navigation along a route, as well as origin and destination geographical locations.

Abstract: An online system provides navigation information customized using travel preferences of users. The online system receives actions performed by users that may indicate their geographical locations of interest. The online system may use a model to predict a user's level of interest in destination geographical locations. The online system generates navigation information or travel information that describes routes from origin geographical locations of users to destination geographical locations to which the users are likely to travel. The online system transmits the navigation information to client devices for presentation as personalized or dynamically-created content items to users. The online system may generate navigation information using catalogs describing routes between geographical locations. For instance, the catalog indicates a vehicle for navigation along a route, as well as origin and destination geographical locations.

Abstract: Provided herein are methods and compositions for treating cancer in an individual comprising administering to the individual an effective amount of a TLR agonist and a chimeric CD154 polypeptide. Also provided herein are methods of enhanced immune function.

Abstract: An integrated network security enforcement system is provided. Information from a network access control (NAC) device, network analytics engine (NAE) executing on a network analytics server (NAS), and a network controller are used to control network access of a client device and associated user. A login session for the user may be monitored by the NAE. Events based on risk analysis of user-initiated actions are sent to the NAC device and/or the network controller. Events may indicate to take action with respect to the client device (or user). For example, user-initiated actions that cumulatively appear as a security threat on a device (and possibly other devices) may be isolated or forced to re-authenticate. Risk assessment may be reduced if higher levels of authentication are performed by the user. Two-factor, or biometric authentication may allow greater risk (e.g., reduced risk assessment) than a login session using a single password.

Abstract: Provided herein are methods and compositions for treating cancer in an individual comprising administering to the individual an effective amount of at least one immune checkpoint inhibitor and a chimeric CD 154 polypeptide. Also provided herein are methods of enhanced immune function.

Abstract: Aspects of the disclosure are directed to DC power management. A sequencer may be configured to execute a first command, wherein the first command is associated with a unique group tag; compare the unique group tag to a master group tag; determine if an interrupt is detected; lock the master group tag to yield a locked master group tag; execute a second command, wherein the second command is associated with the locked master group tag; determine that an end of commands in the locked master group tag is reached and execute a sequence jump through command to put a processor back to a regular power state.

Abstract: An online system uses a model to determine affinities of users for geographical locations. Using the affinities, which may indicate travel-related preferences of the users, the online system may customize content items to include content captured by client devices of other users of the online system. For example, the online system presents to a particular user a content item including a photo or video of a geographical location captured by a camera of a client device of another user who is connected to the particular user. The model may implement, for example, collaborative filtering or other machine learning techniques to determine commonalities between users' travel affinities. Additionally, the model may determine latent properties or temporal trends of user preferences based on training data including historical actions performed on the online system or social data. The model may also classify different types of geographical locations.

Abstract: Aspects of the disclosure are directed to DC power management. A sequencer may be configured to execute a first command, wherein the first command is associated with a unique group tag; compare the unique group tag to a master group tag; determine if an interrupt is detected; lock the master group tag to yield a locked master group tag; execute a second command, wherein the second command is associated with the locked master group tag; determine that an end of commands in the locked master group tag is reached and execute a sequence jump through command to put a processor back to a regular power state.

Abstract: The amorphous form of trisodium sacubitril valsartan and methods for the preparation thereof are disclosed herein.

Abstract: A biopsy processing system designed to prevent lodging and possible loss of the tissue specimen for analysis. The system includes a biopsy container having a longitudinal wall forming an internal compartment, a biopsy bag attached to an inner surface of the container, a cassette for receiving the biopsy bag, and an automated system for removing the biopsy bag from the biopsy container and placing the biopsy bag in the cassette.

Abstract: Embodiments of the disclosed subject matter can provide techniques for synchronizing data acquisition (DAQ) modules in a data acquisition system. In data acquisition systems where multiple DAQ modules are in use, it can be desirable to synchronize the DAQ modules to facilitate the analysis of signals captured by sensors coupled to those DAQ modules. This way, a signal processing platform, such as a computer, can analyze different sensor signals (e.g., an audio sensor and vibration sensor) without separately compensating for the time difference between the audio and vibration signals. In some embodiments, the synchronization techniques can include an automatic or a semi-automatic mechanism for temporally synchronizing the sensors and for arbitrating the sampling rate between the data acquisition systems.

Abstract: A biopsy processing system designed to prevent lodging and possible loss of the tissue specimen for analysis. The system includes a biopsy container having a longitudinal wall forming an internal compartment, a biopsy bag attached to an inner surface of the container, a cassette for receiving the biopsy bag, and an automated system for removing the biopsy bag from the biopsy container and placing the biopsy bag in the cassette.

Abstract: A biopsy pipette with a filter attached in an internal compartment of a pipette designed to prevent lodging and possible loss of the tissue specimen for analysis. A biopsy test tube may be provided with a biopsy bag attached in the internal compartment of the test tube. Further, a biopsy cassette may be provided with an opening configured to receive a pipette. An automated and non-automated system and method of using the biopsy pipette, biopsy test tube, and biopsy cassette in the processing of biopsy specimen is also disclosed.

Abstract: A biopsy pipette with a filter attached in an internal compartment of a pipette designed to prevent lodging and possible loss of the tissue specimen for analysis. A biopsy test tube may be provided with a biopsy bag attached in the internal compartment of the test tube. Further, a biopsy cassette may be provided with an opening configured to receive a pipette. An automated and non-automated system and method of using the biopsy pipette, biopsy test tube, and biopsy cassette in the processing of biopsy specimen is also disclosed.