Abstract: The present invention relates to a medical device delivery system. The delivery system includes an introducer sheath having an elongated tubular member having a passageway extending generally longitudinally therethrough. The passageway is defined by an inner surface of the tubular member and is configured to receive a medical device moveably disposed therein, where at least a portion of the inner surface of the inner tube comprises a non-uniform surface configured to reduce surface contact between the inner surface and the medical device. The delivery system includes an inner catheter configured to slidably extend throughout the passageway of the introducer sheath. A prosthesis is disposed within a distal portion of the introducer sheath, where the prosthesis is supported within the introducer sheath by the inner catheter.

Abstract: Drug coated stents for implantation in a body vessel are provided. A stent can include a plasma treatment on the luminal surface and a protein-adherence deterring layer on at least a portion of the luminal surface. A further embodiment includes a method of manufacturing a drug coated stent. Another further embodiment includes a method of treating a vascular condition with a drug coated stent.