Patents by Inventor Manjunath N. Swamy

Manjunath N. Swamy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CD70 inhibition for the treatment and prevention of inflammatory bowel disease
    Patent number: 7615211
    Abstract: Substantially purified populations of APCLP cells capable of expressing CD70 are described. Also described are methods for the treatment of certain diseases and medical conditions of the gastrointestinal tract, such as inflammatory bowel disease, by utilizing inhibitors of CD70 activity.
    Type: Grant
    Filed: February 8, 2005
    Date of Patent: November 10, 2009
    Assignee: CBR Institute for Biomedical Research, Inc.
    Inventors: Manjunath N. Swamy, Amale Laouar
  • Method to Treat Flavivirus Infection with siRNA
    Publication number: 20090047338
    Abstract: The present invention is directed to methods of treating flavivirus mediated diseases using siRNAs. The invention is based upon our findings in a mouse model that siRNAs directed against sequences conserved among multiple flaviviruses prevents and treats flavivirus infections. Accordingly, the present invention provides an isolated siRNA comprising a sense RNA and an antisense RNA strand or a single strand. The sense and the antisense RNA strands, or the single RNA strand, form an RNA duplex, and wherein the RNA strand comprises a nucleotide sequence identical to a target sequence of about 15 to about 30 contiguous nucleotides in flavivirus mRNA or mutant or variant thereof.
    Type: Application
    Filed: October 5, 2006
    Publication date: February 19, 2009
    Applicant: IMMUNE DISEASE INSTITUTE, INC.
    Inventors: Manjunath N. Swamy, Premlata Shankar, Priti Kumar, Sang-Kyung Lee