Patents by Inventor Manman XIE

Manman XIE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TMEM59 PROTEIN DIMER OR CHIMERIC EXPRESSION RECEPTOR IMPROVING T CELL FUNCTION
    Publication number: 20220380433
    Abstract: The present invention relates to an immune cell, which contains a TMEM59 protein and/or a functional fragment thereof, a chimeric antigen receptor (CAR) and/or a coding element thereof, as well as a use of the immune cell in the preparation of a drug for treating tumors. Further provided are a method for promoting the proliferation of immune cells and a method for promoting the production of memory cells.
    Type: Application
    Filed: November 12, 2020
    Publication date: December 1, 2022
    Applicant: SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.
    Inventors: Xuemei LIAO, Jingwei HUANG, Zhuo CHEN, Yang LIU, Xiaocui CHENG, Manman XIE, Rongfang SUN, Yingying LI, Guangxin XIA, Ying KE, Yanjun LIU
  • IMMUNE CELL CONTAINING TUMOR ANTIGEN RECOGNITION RECEPTOR AND APPLICATION THEREOF
    Publication number: 20220195397
    Abstract: A modified immune effector cell and a use thereof, a cell population containing the immune effector cell, and a pharmaceutical composition. The expression and/or activity of an S1PR1 protein of the modified immune effector cell is up-regulated.
    Type: Application
    Filed: April 3, 2020
    Publication date: June 23, 2022
    Applicant: SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.
    Inventors: Xuemei LIAO, Jingwei HUANG, Zhuo CHEN, Manman XIE, Andi LI, Yang LIU, Guangxin XIA, Yanjun LIU, Ying KE