Patents by Inventor Manny D. Bacolod

Manny D. Bacolod has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230285570
    Abstract: The present application is directed to a therapeutically useful monomer comprising a linker element and an E3 ubiquitin ligase binding moiety. The linker and the E3 ubiquitin ligase binding moiety are covalently coupled to each other either directly or through an optional connector moiety.
    Type: Application
    Filed: August 4, 2021
    Publication date: September 14, 2023
    Inventors: Francis BARANY, Sarah F. GIARDINA, Manny D. BACOLOD, Pradeep K. SINGH, J. David WARREN
  • Publication number: 20230287484
    Abstract: The present invention relates to methods for identifying and/or quantifying low abundance, nucleotide base mutations, insertions, deletions, translocations, splice variants, miRNA variants, alternative transcripts, alternative start sites, alternative coding sequences, alternative non-coding sequences, alternative splicings, exon insertions, exon deletions, intron insertions, or other rearrangement at the genome level and/or methylated or hydroxymethylated nucleotide bases, as well as markers to identify early cancer, monitor cancer treatment, and identify early cancer recurrence.
    Type: Application
    Filed: April 29, 2021
    Publication date: September 14, 2023
    Inventors: Francis BARANY, Manny D. BACOLOD, Jianmin HUANG, Philip B. FEINBERG, Aashiq H. MIRZA, Sarah F. GIARDINA
  • Publication number: 20220243263
    Abstract: The present invention relates to methods for identifying and/or quantifying low abundance, nucleotide base mutations, insertions, deletions, translocations, splice variants, miRNA variants, alternative transcripts, alternative start sites, alternative coding sequences, alternative non-coding sequences, alternative splicings, exon insertions, exon deletions, intron insertions, or other rearrangement at the genome level and/or methylated nucleotide bases.
    Type: Application
    Filed: May 1, 2020
    Publication date: August 4, 2022
    Inventors: Francis BARANY, Manny D. BACOLOD, Jianmin HUANG, Aashiq H. MIRZA, Philip B. FEINBERG, Sarah F. GIARDINA
  • Publication number: 20220205050
    Abstract: The present application relates to methods for identifying and/or quantifying low abundance, nucleotide base mutations, insertions, deletions, translocations, splice variants, miRNA variants, alternative transcripts, alternative start sites, alternative coding sequences, alternative non-coding sequences, alternative splicings, exon insertions, exon deletions, intron insertions, or other rearrangement at the genome level and/or methylated or hydroxymethylated nucleotide bases, as well as markers to identify early cancer, monitor cancer treatment, and identify early cancer recurrence.
    Type: Application
    Filed: May 1, 2020
    Publication date: June 30, 2022
    Inventors: Francis BARANY, Manny D. BACOLOD, Jianmin HUANG, Philip FEINBERG, Aashiq MIRZA, Sarah GIARDINA
  • Publication number: 20110257034
    Abstract: Closures for containers and methods for using same are provided. In a general embodiment/the present disclosure provides a closure having a top portion (12), a bottom portion (14) and a side portion (16), an aperture (18) extending though the closure, a projection (20) extending from the closure and at least two rib members (36) on an interior of the projection. The projection may also include a cover (22). In another embodiment, a method for using a closure includes inserting a. spike member into a projection, piercing a membrane that hermetically seals a medical container, pushing rib members within the projection to center the spike member inserted into the projection, and tearing the membrane to create a vent hole in the membrane.
    Type: Application
    Filed: October 13, 2009
    Publication date: October 20, 2011
    Applicants: CORNELL UNIVERSITY, THE TRUSTEES OF PRINCETON UNIVERSITY, SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH, UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
    Inventors: Francis Barany, Owen Parker, Manny D. Bacolod, Sarah F. Giardina, Yu-wei Cheng, Daniel A. Notterman, Gunter S. Schemmann, Philip B. Paty, Monib Zirvi