Patents by Inventor Manoj Kumar Ramjee

Manoj Kumar Ramjee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of producing conjugate vaccines
    Publication number: 20080213297
    Abstract: The present invention relates to a method of production of a hydrazide modified sugar comprising a step of reacting a sugar with a hydrazide in a reaction solvent at a pH of between 3 and 5.5, wherein the solvent comprises an aqueous based solvent and an optional polar organic co-solvent. A further aspect of the invention relates to a method of production of a polysaccharide epitope carrier protein conjugate comprising the steps of: (a) reacting a polysaccharide epitope with a hydrazide to form a hydrazide modified polysaccharide epitope; (b) reacting the hydrazide modified polysaccharide epitope with a linker that has been pre-coupled to a carrier protein.
    Type: Application
    Filed: July 16, 2007
    Publication date: September 4, 2008
    Inventors: Nicholas Finn, Martin Quibell, Manoj Kumar Ramjee, William Gordon Turnell
  • Inhibitors of cruzipain and other cysteine proteases
    Patent number: 6958358
    Abstract: Compounds of general formula (I): wherein R1, Y, (X)o, (W)n, (V)m, Z and U are as defined in the specification, are inhibitors of cruzipain and other cysteine protease inhibitors and are useful as therapeutic agents, for example in Chagas' disease, or for validating therapeutic target compounds.
    Type: Grant
    Filed: January 17, 2002
    Date of Patent: October 25, 2005
    Assignee: Amura Therapeutics Limited
    Inventors: Martin Quibell, Manoj Kumar Ramjee
  • Inhibitors of cruzipain and other cysteine proteases
    Publication number: 20040106805
    Abstract: Compounds of general formula (I): wherein R1, Y, (X)0, (W)n, (V)m, Z and U are as defined in the specification, are inhibitors of cruzipain and other cysteine protease inhibitors and are useful as therpeutic agents, for example in Chagas' disease, or for validating therapeutic target compounds.
    Type: Application
    Filed: January 8, 2004
    Publication date: June 3, 2004
    Inventors: Martin Quibell, Manoj Kumar Ramjee