Patents by Inventor Manoj Nerurkar

Manoj Nerurkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Controlled release sterile injectable aripiprazole formulation and method
    Patent number: 8598178
    Abstract: A controlled release sterile freeze-dried aripiprazole formulation is provided which is formed of aripiprazole of a desired mean particle size and a vehicle therefor, which upon constitution with water and intramuscular injection releases aripiprazole over a period of at least about one week and up to about eight weeks. A method for preparing the controlled release freeze-dried aripiprazole formulation, and a method for treating schizophrenia employing the above formulation are also provided.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: December 3, 2013
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Janusz W. Kostanski, Takakuni Matsuda, Manoj Nerurkar, Vijay H. Naringrekar
  • Stable protein formulations
    Patent number: 8476239
    Abstract: The present invention relates generally to stable formulations comprising CTLA4Ig molecules, including lyophilized, and liquid formulations for administration via various routes including, for example, routes such as intravenous (IV) and subcutaneous (SC) for treating immune system diseases and tolerance induction.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: July 2, 2013
    Assignee: Bristol-Myers Squibb Company
    Inventors: Manisha M. Dali, Charles E. Dahlheim, Sunita Borsadia, Vijay H. Naringrekar, Rajesh Babulal Gandhi, Manoj Nerurkar
  • CONTROLLED RELEASE STERILE INJECTABLE ARIPIPRAZOLE FORMULATION AND METHOD
    Publication number: 20120100190
    Abstract: A controlled release sterile freeze-dried aripiprazole formulation is provided which is formed of aripiprazole of a desired mean particle size and a vehicle therefor, which upon constitution with water and intramuscular injection releases aripiprazole over a period of at least about one week and up to about eight weeks. A method for preparing the controlled release freeze-dried aripiprazole formulation, and a method for treating schizophrenia employing the above formulation are also provided.
    Type: Application
    Filed: December 28, 2011
    Publication date: April 26, 2012
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Janusz W. Kostanski, Takakuni Matsuda, Manoj Nerurkar, Vijay H. Naringrekar
  • ARIPIPRAZOLE COMPLEX FORMULATION AND METHOD
    Publication number: 20120053145
    Abstract: An aripiprazole formulation is provided which includes the antipsychotic agent aripiprazole in the form of an inclusion complex in a ?-cyclodextrin, preferably, sulfobutyl ether ?-cyclodextrin (SBECD), which in the form of an injectable produces reversible generally minimal to mild irritation at the intramuscular injection site. A method for minimizing or reducing irritation caused by aripiprazole at an intramuscular injection site and a method for treating schizophrenia employing the above formulation are also provided.
    Type: Application
    Filed: November 3, 2011
    Publication date: March 1, 2012
    Inventors: MANOJ NERURKAR, Vijay Naringrekar
  • Controlled release sterile injectable aripiprazole formulation and method
    Patent number: 8030313
    Abstract: A controlled release sterile freeze-dried aripiprazole formulation is provided which is formed of aripiprazole of a desired mean particle size and a vehicle therefor, which upon constitution with water and intramuscular injection releases aripiprazole over a period of at least about one week and up to about eight weeks. A method for preparing the controlled release freeze-dried aripiprazole formulation, and a method for treating schizophrenia employing the above formulation are also provided.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: October 4, 2011
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Janusz W. Kostanski, Takakuni Matsuda, Manoj Nerurkar, Vijay H. Naringrekar
  • ARIPIPRAZOLE COMPLEX FORMULATION AND METHOD
    Publication number: 20110160224
    Abstract: An aripiprazole formulation is provided which includes the antipsychotic agent aripiprazole in the form of an inclusion complex in a ?-cyclodextrin, preferably, sulfobutyl ether ?-cyclodextrin (SBECD), which in the form of an injectable produces reversible generally minimal to mild irritation at the intramuscular injection site. A method for minimizing or reducing irritation caused by aripiprazole at an intramuscular injection site and a method for treating schizophrenia employing the above formulation are also provided.
    Type: Application
    Filed: March 11, 2011
    Publication date: June 30, 2011
    Inventors: Manoj NERURKAR, Vijay NARINGREKAR
  • Controlled release sterile injectable aripiprazole formulation and method
    Patent number: 7807680
    Abstract: A controlled release sterile freeze-dried aripiprazole formulation is provided which is formed of aripiprazole of a desired mean particle size and a vehicle therefor, which upon constitution with water and intramuscular injection releases aripiprazole over a period of at least about one week and up to about eight weeks. A method for preparing the controlled release freeze-dried aripiprazole formulation, and a method for treating schizophrenia employing the above formulation are also provided.
    Type: Grant
    Filed: October 19, 2004
    Date of Patent: October 5, 2010
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Janusz W. Kostanski, Takakuni Matsuda, Manoj Nerurkar, Vijay H. Naringrekar
  • Stable Protein Formulations
    Publication number: 20100166774
    Abstract: The present invention relates generally to stable formulations comprising CTLA4Ig molecules, including lyophilized, and liquid formulations for administration via various routes including, for example, routes such as intravenous (IV) and subcutaneous (SC) for treating immune system diseases and tolerance induction.
    Type: Application
    Filed: December 19, 2006
    Publication date: July 1, 2010
    Inventors: Manisha M. Dali, Charles E. Dahlheim, Sunita Borsadia, Vijay H. Naringrekar, Rajesh Babulal Gandhi, Manoj Nerurkar
  • ARIPIPRAZOLE COMPLEX FORMULATION AND METHOD
    Publication number: 20090186903
    Abstract: An aripiprazole formulation is provided which includes the antipsychotic agent aripiprazole in the form of an inclusion complex in a ?-cyclodextrin, preferably, sulfobutyl ether ?-cyclodextrin (SBECD), which in the form of an injectable produces reversible generally minimal to mild irritation at the intramuscular injection site. A method for minimizing or reducing irritation caused by aripiprazole at an intramuscular injection site and a method for treating schizophrenia employing the above formulation are also provided.
    Type: Application
    Filed: April 2, 2009
    Publication date: July 23, 2009
    Inventors: Manoj Nerurkar, Vijay Naringrekar
  • Aripiprazole complex formulation and method
    Patent number: 7550445
    Abstract: An aripiprazole formulation is provided which includes the antipsychotic agent aripiprazole in the form of an inclusion complex in a ?-cyclodextrin, preferably, sulfobutyl ether ?-cyclodextrin (SBECD), which in the form of an injectable produces reversible generally minimal to mild irritation at the intramuscular injection site. A method for minimizing or reducing irritation caused by aripiprazole at an intramuscular injection site and a method for treating schizophrenia employing the above formulation are also provided.
    Type: Grant
    Filed: June 14, 2006
    Date of Patent: June 23, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Manoj Nerurkar, Vijay Naringrekar
  • Controlled release sterile injectable aripiprazole formulation and method
    Publication number: 20080112986
    Abstract: A controlled release sterile freeze-dried aripiprazole formulation is provided which is formed of aripiprazole of a desired mean particle size and a vehicle therefor, which upon constitution with water and intramuscular injection releases aripiprazole over a period of at least about one week and up to about eight weeks. A method for preparing the controlled release freeze-dried aripiprazole formulation, and a method for treating schizophrenia employing the above formulation are also provided.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 15, 2008
    Inventors: Janusz Kostanski, Takakuni Matsuda, Manoj Nerurkar, Vijay Naringrekar
  • Controlled release sterile injectable aripiprazole formulation and method
    Publication number: 20080112985
    Abstract: A controlled release sterile freeze-dried aripiprazole formulation is provided which is formed of aripiprazole of a desired mean particle size and a vehicle therefor, which upon constitution with water and intramuscular injection releases aripiprazole over a period of at least about one week and up to about eight weeks. A method for preparing the controlled release freeze-dried aripiprazole formulation, and a method for treating schizophrenia employing the above formulation are also provided.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 15, 2008
    Inventors: Janusz Kostanski, Takakuni Matsuda, Manoj Nerurkar, Vijay Naringrekar
  • Controlled release sterile injectable aripiprazole formulation and method
    Publication number: 20080107745
    Abstract: A controlled release sterile freeze-dried aripiprazole formulation is provided which is formed of aripiprazole of a desired mean particle size and a vehicle therefor, which upon constitution with water and intramuscular injection releases aripiprazole over a period of at least about one week and up to about eight weeks. A method for preparing the controlled release freeze-dried aripiprazole formulation, and a method for treating schizophrenia employing the above formulation are also provided.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 8, 2008
    Inventors: Janusz Kostanski, Takakuni Matsuda, Manoj Nerurkar, Vijay Naringrekar
  • Aripiprazole complex formulation and method
    Publication number: 20060234979
    Abstract: An aripiprazole formulation is provided which includes the antipsychotic agent aripiprazole in the form of an inclusion complex in a ?-cyclodextrin, preferably, sulfobutyl ether ?-cyclodextrin (SBECD), which in the form of an injectable produces reversible generally minimal to mild irritation at the intramuscular injection site. A method for minimizing or reducing irritation caused by aripiprazole at an intramuscular injection site and a method for treating schizophrenia employing the above formulation are also provided.
    Type: Application
    Filed: June 14, 2006
    Publication date: October 19, 2006
    Inventors: Manoj Nerurkar, Vijay Naringrekar
  • Aripiprazole complex formulation and method
    Patent number: 7115587
    Abstract: An aripiprazole formulation is provided which includes the antipsychotic agent aripiprazole in the form of an inclusion complex in a ?-cyclodextrin, preferably, sulfobutyl ether ?-cyclodextrin (SBECD), which in the form of an injectable produces reversible generally minimal to mild irritation at the intramuscular injection site. A method for minimizing or reducing irritation caused by aripiprazole at an intramuscular injection site and a method for treating schizophrenia employing the above formulation are also provided.
    Type: Grant
    Filed: August 14, 2003
    Date of Patent: October 3, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Manoj Nerurkar, Vijay Naringrekar
  • Controlled release sterile injectable aripiprazole formulation and method
    Publication number: 20050148597
    Abstract: A controlled release sterile freeze-dried aripiprazole formulation is provided which is formed of aripiprazole of a desired mean particle size and a vehicle therefor, which upon constitution with water and intramuscular injection releases aripiprazole over a period of at least about one week and up to about eight weeks. A method for preparing the controlled release freeze-dried aripiprazole formulation, and a method for treating schizophrenia employing the above formulation are also provided.
    Type: Application
    Filed: October 19, 2004
    Publication date: July 7, 2005
    Inventors: Janusz Kostanski, Takakuni Matsuda, Manoj Nerurkar, Vijay Naringrekar
  • Aripiprazole complex formulation and method
    Publication number: 20040077594
    Abstract: An aripiprazole formulation is provided which includes the antipsychotic agent aripiprazole in the form of an inclusion complex in a &bgr;-cyclodextrin, preferably, sulfobutyl ether &bgr;-cyclodextrin (SBECD), which in the form of an injectable produces reversible generally minimal to mild irritation at the intramuscular injection site. A method for minimizing or reducing irritation caused by aripiprazole at an intramuscular injection site and a method for treating schizophrenia employing the above formulation are also provided.
    Type: Application
    Filed: August 14, 2003
    Publication date: April 22, 2004
    Inventors: Manoj Nerurkar, Vijay Naringrekar, Mark Dominick