Patents by Inventor Manoj Ramesh Kharkar

Manoj Ramesh Kharkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing (2R,3S/2S,3R)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
    Patent number: 8039619
    Abstract: Voriconazole is prepared by a process comprising condensing 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazole-1-yl)ethanone with 4-chloro-6-ethyl-5-fluoropyrimidine, in a ketone, ether, aliphatic hydrocarbon, or aromatic hydrocarbon solvent, to give (2R,3S/2S,3R)-3-(4-chloro-5-fluoropyrimidin-6-yl)-2-(2,4-diflurophenyl)-1-(1H -1,2,4-triazole-1-yl)butan-2-ol.
    Type: Grant
    Filed: June 10, 2010
    Date of Patent: October 18, 2011
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Venkataraman Sundaram, Venkata Bhaskara Rao Uppala, Surya Prabhakar Akundi, Venkateswarlu Muvva, Vijayawardhan Chitta, Alekhya Donthula, Manoj Ramesh Kharkar, Surya Narayana Devarakonda, Subba Reddy Peddireddy
  • PROCESS FOR PREPARING (2R,3S/2S,3R)-2-(2,4-DIFLUOROPHENYL)-3-(5-FLUOROPYRIMIDIN-4-YL)-1-(1H-1,2,4-TRIAZOL-1-YL)BUTAN-2-OL
    Publication number: 20100292473
    Abstract: Voriconazole is prepared by a process comprising condensing 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazole-1-yl)ethanone with 4-chloro-6-ethyl-5-fluoropyrimidine, in a ketone, ether, aliphatic hydrocarbon, or aromatic hydrocarbon solvent, to give (2R,3S/2S,3R)-3-(4-chloro-5-fluoropyrimidin-6-yl)-2-(2,4-diflurophenyl)-1-(1H-1,2,4-triazole-1-yl)butan-2-ol.
    Type: Application
    Filed: June 10, 2010
    Publication date: November 18, 2010
    Applicants: DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
    Inventors: Venkataraman Sundaram, Venkata Bhaskara Rao Uppala, Surya Prabhakar Akundi, Venkateswarlu Muvva, Vijayawardhan Chitta, Alekhya Donthula, Manoj Ramesh Kharkar, Surya Narayana Devarakonda, Subba Reddy Peddireddy
  • PROCESS FOR THE PREPARATION OF 5-(2-(4-(1,2-BENZISOTHIAZOL-3-YL)-1-PIPERAZINYL) ETHYL)-6-CHLORO-1, 3-DIHYDRO-2H-INDOL-2-ONE HYDROCHLORIDE (ZIPRASIDONE HYDROCHLORIDE) AND ITS INTERMEDIATE
    Publication number: 20090047354
    Abstract: The present invention relates to improved processes for the preparation of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one and its hydrochloride, which is known as Ziprasidone hydrochloride of Formula (I) and 5-(2-Chloro acetyl)-6-chloro oxindole of Formula (IV), which is an intermediate for the preparation of 5-(2-chloro ethyl)-6-chloro oxindole of Formula (V). Ziprasidone hydrochloride of Formula (I) of the present invention is depicted by the following structure.
    Type: Application
    Filed: April 24, 2008
    Publication date: February 19, 2009
    Applicants: DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
    Inventors: Manne Satyanarayana Reddy, Sundaram Venkatraman, Srinivasan Thirumalai Rajan, Sharat Pandurang Narsapur, Manoj Ramesh Kharkar, Surya Narayana Devarkonda, Yarraguntla Sesha Reddy, Rangineni Srinivasulu, Deepak K. Shukla, Pushkar B. Lakhekar, Uppala Venkata Bhaskar Rao, Mummadi Venkatesh
  • Process For Preparing Voriconazole
    Publication number: 20080194820
    Abstract: Voriconazole is prepared by a process comprising condensing 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazole-1-yl)ethanone with 4-chloro-6-ethyl-5-fluoropyrimidine, in a ketone, ether, aliphatic hydrocarbon, or aromatic hydrocarbon solvent, to give (2R, 3S/2S,3R)-3-(4-chloro-5-fluoropyrimidin-6-yl)-2-(2,4-diflurophenyl)-1-(1H-1,2,4-triazole-1-yl)butan-2-ol.
    Type: Application
    Filed: December 13, 2005
    Publication date: August 14, 2008
    Inventors: Venkataraman Sundaram, Venkata Bhaskara Rao Uppala, Surya Prabhakar Akundi, Venkateswarlu Muvva, Vijayawardhan Chitta, Alekhya Donthula, Manoj Ramesh Kharkar, Surya Narayana Devarakonda, Subba Reddy Peddireddy
  • Stable Nateglinide Form B Compositions
    Publication number: 20080096970
    Abstract: A process for preparing nateglinide Form B comprises dissolving nateglinide in a solvent and adding the solution, at temperatures of 40-45° C., to a hydrocarbon liquid that is at temperatures of 40-45° C. Then, water is added and the mixture is allowed to cool, producing crystals of nateglinide Form B.
    Type: Application
    Filed: May 20, 2005
    Publication date: April 24, 2008
    Inventors: Sundaram Venkataraman, Sharat Pandurang Narsapur, Manoj Ramesh Kharkar, Rongali Bangarubabu, Mohanty Sandeep, Pyne Sayantani, Kakartapudi Ranga Raju
  • PREPARATION OF ROSIGLITAZONE AND ITS SALTS
    Publication number: 20070293546
    Abstract: The present invention relates to rosiglitazone and its pharmaceutically acceptable salts free of at least one of the process related impurities, in particular the dehydro and the succinic acid impurities of rosiglitazone, wherein said impurities are present in an amount of about 05 mg to not more than about 15 mg, and processes for their preparation.
    Type: Application
    Filed: June 15, 2007
    Publication date: December 20, 2007
    Inventors: Srinivasula Reddy Maddula, Kushal Surajmal Manudhane, Sridhar Thota, Arvind Mallinath Lali, Sandeep Bhaskar Kale, Venkata Naga Brahmeswara Rao Mandava, Radhakrishna Singam Setty, Sandeep Mohonty, Jaga Gangaraju Pericherla, Manoj Ramesh Kharkar