Abstract: Described herein are pharmaceutical formulations comprising a MALT1 inhibitor and a mixture comprising fatty acid and polyethylene glycol monoesters and diesters, and optionally, fatty acid and glycerol monoesters, diesters and triesters. Solid dosage forms comprising said pharmaceutical formulations, processes for preparing these and their use in methods of treatment are also described.

Abstract: The invention relates to pharmaceutical formulations comprising an active pharmaceutical ingredient, a polyethylene glycol having a freezing point of at least about 30° C., and a crystallisation rate inhibitor. Solid dosage forms comprising said pharmaceutical formulations, processes for preparing these and their use in methods of treatment are also described.

Abstract: In one embodiment an apparatus can include a plurality of magnetic material layers. In one embodiment, an apparatus can include one or more electrically insulating layer, wherein the plurality of magnetic material layers and the one or more electrically insulating layer define a stacked up structure, wherein an electrically insulating layer of the one or more electrically insulating layer includes thermally conductive dielectric material.

Abstract: The invention relates to novel cells and cell lines, and methods for making and using them.

Abstract: The present invention is based on applicants' discovery, disclosed herein, of agonists for the TAS2R receptors TAS2R1, TAS2R4, TAS2R9, TAS2R13, TAS2R14, TAS2R16, TAS2R44, TAS2R46, and TAS2R60. The assignment of agonists to these receptors makes assays for identifying compounds that modulate bitter taste possible. For example, the present invention provides methods of identifying compounds that inhibit the bitter taste due to these agonists. The present invention also provides methods of identifying compounds that selectively inhibit the bitter taste due to these agonists. The present invention further provides methods of identifying compounds that mimic the bitter taste due these agonists. The present invention also provides methods of identifying compounds that enhance the bitter taste due to these agonists.

Abstract: The present invention is based on applicants' discovery, disclosed herein, of agonists for the TAS2R receptors TAS2R1, TAS2R4, TAS2R9, TAS2R13, TAS2R14, TAS2R16, TAS2R44, TAS2R46, and TAS2R60. The assignment of agonists to these receptors makes assays for identifying compounds that modulate bitter taste possible. For example, the present invention provides methods of identifying compounds that inhibit the bitter taste due to these agonists. The present invention also provides methods of identifying compounds that selectively inhibit the bitter taste due to these agonists. The present invention further provides methods of identifying compounds that mimic the bitter taste due these agonists. The present invention also provides methods of identifying compounds that enhance the bitter taste due to these agonists.

Abstract: A liquid detection system includes an absorbent article for personal wear having a liquid permeable liner, an outer cover, and an absorbent body disposed between the liner and the outer cover. The article also includes at least one graphic element, a conductive pattern at least partially superposed with the graphic element, and a barrier layer disposed between the graphic element and the conductive pattern. A non-invasive signaling device is selectively attachable to the outer cover of the absorbent article in overlying relationship with the conductive pattern. The signaling device is adapted to detect the presence of liquid within the absorbent article.

Abstract: A rotor core is provided for an electric machine. The rotor core includes a body extending a length along, and being configured to rotate about, a central longitudinal axis. The body includes spokes arranged radially about the central longitudinal axis and conductor openings arranged radially about the central longitudinal axis. The radial arrangement of the spokes and conductor openings about the central longitudinal axis includes an alternating pattern of spokes and conductor openings. The spokes include slots extending therethrough along the central longitudinal axis. The slots are positioned radially about the central longitudinal axis between adjacent conductor openings. The rotor core also includes conductors extending within the conductor openings of the body.

Abstract: The present invention is based on applicants' discovery, disclosed herein, of agonists for the TAS2R receptors TAS2R1, TAS2R4, TAS2R9, TAS2R13, TAS2R14, TAS2R16, TAS2R44, TAS2R46, and TAS2R60. The assignment of agonists to these receptors makes assays for identifying compounds that modulate bitter taste possible. For example, the present invention provides methods of identifying compounds that inhibit the bitter taste due to these agonists. The present invention also provides methods of identifying compounds that selectively inhibit the bitter taste due to these agonists. The present invention further provides methods of identifying compounds that mimic the bitter taste due these agonists. The present invention also provides methods of identifying compounds that enhance the bitter taste due to these agonists.

Abstract: A liquid detection system includes an absorbent article for personal wear having a liquid permeable liner, an outer cover, and an absorbent body disposed between the liner and the outer cover. The article also includes at least one graphic element, a conductive pattern at least partially superposed with the graphic element, and a barrier layer disposed between the graphic element and the conductive pattern. A non-invasive signaling device is selectively attachable to the outer cover of the absorbent article in overlying relationship with the conductive pattern. The signaling device is adapted to detect the presence of liquid within the absorbent article.

Abstract: A rotor core is provided for an electric machine. The rotor core includes a body extending a length along, and being configured to rotate about, a central longitudinal axis. The body includes spokes arranged radially about the central longitudinal axis and conductor openings arranged radially about the central longitudinal axis. The radial arrangement of the spokes and conductor openings about the central longitudinal axis includes an alternating pattern of spokes and conductor openings. The spokes include slots extending therethrough along the central longitudinal axis. The slots are positioned radially about the central longitudinal axis between adjacent conductor openings. The rotor core also includes conductors extending within the conductor openings of the body.

Abstract: The present application and the resultant patent provide a superconducting electrical machine. The superconducting electrical machine may include an armature coil made of a high temperature superconducting material, a cooling system, and a field coil. The cooling system may include a cryostat surrounding the armature coil and a foam insulation surrounding the cryostat.

Abstract: A rotor structure for a permanent magnet electromotive machine is provided. A back-core lamination is disposed around a plurality of permanent magnets. The back-core lamination comprises a plurality of high-reluctance regions arranged to attenuate asynchronous magnetic flux components while avoiding synchronous magnetic flux components. The asynchronous and synchronous magnetic flux components result from spatial harmonic components of a plurality of fractional-slot concentrated windings of a stator of the machine.

Abstract: The invention relates to novel cells and cell lines, and methods for making and using them.

Abstract: A process for preparation of milled cocoa shell including grinding cocoa shell in a single unit operation in a short-duration manner without the need for moving mechanical parts. The milled cocoa shell product obtained from the grinding treatment has reduced heat degradation and avoids equipment maintenance concerns otherwise associated with mechanical milling of the cocoa shells while providing an edible granular product useful for food manufacture such as chocolate food production.

Abstract: The present application and the resultant patent provide a superconducting electrical machine. The superconducting electrical machine may include an armature coil made of a high temperature superconducting material, a cooling system, and a field coil. The cooling system may include a cryostat surrounding the armature coil and a foam insulation surrounding the cryostat.

Abstract: A gas turbine engine assembly includes an electromagnetic machine for extracting power from the turbine engine. The electromagnetic machine includes an outer rotor and an inner rotor rotatably supported adjacent to a stator disposed between the inner and outer rotors. The stator has an inner set of windings disposed on an inner surface adjacent to the inner rotor, and an outer set of windings on an outer surface of the stator adjacent to the outer rotor. The inner stator windings form a set of multiple-phase windings, and the outer stator windings form a set of multiple-phase windings.

Abstract: The present invention relates to a pourable food composition, like a dressing, that has at least 2.5 grams of total dietary fiber per 32 gram serving. The fiber is derived from at least one whole fruit or vegetable that is partially or completely dehydrated and which is subjected only to minimal processing. The food composition has a viscosity of about 3,000 to about 12,500 centipoise. The fiber may be derived from whole vegetables that are high in fiber, such as beans, carrots, broccoli and the like. The fiber may also be derived from whole fruits that are high in fiber, such as avocados, mangos, and the like. The whole food is subject to only minimal processing, such as by physical means, enzymatic means, or by fermentative means.

Abstract: A process for selectively grinding dual-density processed food in a single unit operation in a short-duration manner. Selective grinding as between lower-density and higher-density portions of the dual-density processed food may be effected without the need for moving mechanical parts. A granulated lower-density portion and liberated nonground higher-density portion obtained from the selective grinding treatment performed on dual-density processed food are independently useful for re-use in food production lines.

Abstract: An electromagnetic machine for extracting power from a turbine engine includes an outer rotor and an inner rotor rotatably supported adjacent to a stator. The stator is disposed between the inner and outer rotors. The stator has an inner set of windings disposed on an inner surface adjacent to the inner rotor, and an outer set of windings on an outer surface of the stator adjacent to the outer rotor. A plurality of permanent magnets are disposed on an inner surface of the outer rotor element and on an outer surface of the inner rotor element. Air gaps are defined between the outer surface of the stator and the outer permanent magnets, and between the inner surface of the stator portion and the inner permanent magnets. The inner stator windings form a set of multiple-phase windings. and the outer stator windings form a set of multiple-phase windings.