Patents by Inventor Manoj Shukla

Manoj Shukla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enantiomerically pure compounds for the treatment of proliferative disorders
    Patent number: 8563596
    Abstract: The present invention relates to an enantiomerically pure (+)-trans enantiomer of a compound represented by the following formula (I): wherein R1, R2, R3, R4 and R9 are as defined in the specification; enantiomerically pure intermediates thereof, to processes for the preparation of the enantiomerically pure compound and its intermediates, and to a pharmaceutical composition comprising the enantiomerically pure compound. The compound of formula (I) is useful for the treatment of diseases or disorders mediated by the inhibition of cyclin dependant kinase, such as cancer.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: October 22, 2013
    Assignee: Piramal Enterprises Limited
    Inventors: Meenakshi Sivakumar, Malcolm Mascarenhas, Ankush Sarde, Pramod Kumar Jadhav, Manoj Shukla, Kalpana Joshi, Maggie Rathos
  • Enantioselective synthesis of pyrrolidines substituted with flavones, and intermediates thereof
    Patent number: 7951961
    Abstract: The present invention relates to an enantioselective synthesis of (+)-trans enantiomer of pyrrolidines substituted with flavones, represented by Formula 1 or salts thereof, which are inhibitors of cyclin dependant kinases and can be used for treatment of proliferative disorders such as cancer wherein Ar has the meaning as indicated in the claims.
    Type: Grant
    Filed: July 7, 2006
    Date of Patent: May 31, 2011
    Assignee: Piramal Life Sciences Limited
    Inventors: Meenakshi Sivakumar, Manoj Shukla, Pramod Kumar Jadhav, Ajit Borhade
  • NOVEL ENANTIOMERICALLY PURE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS
    Publication number: 20100179210
    Abstract: The present invention relates to an enantiomerically pure (+)-trans-enantiomer of a compound represented by the following formula (I): wherein R1, R2, R3, R4 and R9 are as defined in the specification; enantiomerically pure intermediates thereof, to processes for the preparation of the enantiomerically pure compound and its intermediates, and to a pharmaceutical composition comprising the enantiomerically pure compound. The compound of formula (I) is useful for the treatment of diseases or disorders mediated by the inhibition of cyclin dependant kinase, such as cancer.
    Type: Application
    Filed: June 21, 2006
    Publication date: July 15, 2010
    Inventors: Meenakshi Sivakumar, Malcolm Mascarenhas, Ankush Sarde, Pramod Kumar Jadhav, Manoj Shukla, Kalpana Joshi, Maggie Rathos
  • ENANTIOSELECTIVE SYNTHESIS OF PYRROLIDINES SUBSTITUTED WITH FLAVONES, AND INTERMEDIATES THEREOF
    Publication number: 20100113803
    Abstract: The present invention relates to an enantioselective synthesis of (+)-trans enantiomer of pyrrolidines substituted with flavones, represented by Formula 1 or salts thereof, which are inhibitors of cyclin dependant kinases and can be used for treatment of proliferative disorders such as cancer. wherein Ar has the meaning as indicated in the claims.
    Type: Application
    Filed: July 7, 2006
    Publication date: May 6, 2010
    Inventors: Meenakshi Sivakumar, Manoj Shukla, Pramod Kumar Jadhav, Ajit Borhade