Abstract: An integrated circuit includes an input pad and a Schmitt trigger coupled to the input pad. The Schmitt trigger includes a first inverter and a second inverter. The Schmitt trigger includes a pull-up transistor coupled to an input of the second inverter and configure to supply a high reference voltage to the input of the second inverter.

Abstract: A method using weighted aggregated ensemble model for energy demand management of buildings includes initializing data values for integrated model to measure energy consumption, perform statistical analysis on data values to estimate accurate prediction, optimizing the data values using marine predator optimization for integrated model, analyze the output to minimize the mean square error and results show improvement in accuracy of integrated model. The data values comprise of ?, maximum number of splits, minimum leaf size, and ?. The weighted aggregated ensemble model for energy demand management of buildings shows best performance compared with other predictive models such as linear regression (LR), support vector regression (SVR), multilayer perceptron neural network (MLPNN), decision tree (DT), and generalized additive model (GAM).

Abstract: An integrated circuit includes an input pad and a Schmitt trigger coupled to the input pad. The Schmitt trigger includes a first inverter and a second inverter. The Schmitt trigger includes a pull-up transistor coupled to an input of the second inverter and configure to supply a high reference voltage to the input of the second inverter.

Abstract: A glitch filter is provided. The glitch filter receives an input signal and sets a voltage level of an intermediary input node in accordance with a state of the input signal. The glitch filter charges or discharges a switched capacitance based on the voltage level of the intermediary input node and charges or discharges a filter capacitance based on a charge of the switched capacitance. The glitch filter sets a state of an output signal based on the charge of the filter capacitance. The glitch filter includes a reset stage that at least partially filters a burst of glitches in the input signal from the output signal by controlling the charge of the switched capacitance based on the state of the input signal and the state of the output signal.

Abstract: A glitch filter is provided. The glitch filter receives an input signal and sets a voltage level of an intermediary input node in accordance with a state of the input signal. The glitch filter charges or discharges a switched capacitance based on the voltage level of the intermediary input node and charges or discharges a filter capacitance based on a charge of the switched capacitance. The glitch filter sets a state of an output signal based on the charge of the filter capacitance. The glitch filter includes a reset stage that at least partially filters a burst of glitches in the input signal from the output signal by controlling the charge of the switched capacitance based on the state of the input signal and the state of the output signal.

Abstract: A computer-implemented method for efficiently accessing a secondary storage in highly available clustered storage environment may include receiving a client-initiated data request at a secondary server coupled to a secondary storage; determining request information about the client-initiated data request; determining with the secondary server whether to process the client-initiated data request on the secondary storage based on the determined request information; and responsive to determining that the secondary server should process the client-initiated data request, processing the client-initiated data request by the secondary server to retrieve data from the secondary storage.

Abstract: A computer-implemented method for efficiently accessing a secondary storage in highly available clustered storage environment may include receiving a client-initiated data request at a secondary server coupled to a secondary storage; determining request information about the client-initiated data request; determining with the secondary server whether to process the client-initiated data request on the secondary storage based on the determined request information; and responsive to determining that the secondary server should process the client-initiated data request, processing the client-initiated data request by the secondary server to retrieve data from the secondary storage.

Abstract: The present invention relates to ?-hydroxy and amino-substituted carboxylic acids, which act as matrix metalloproteinase inhibitors, particularly diastereomerically pure ?-hydroxy carboxylic acids, corresponding processes for their synthesis, and pharmaceutical compositions containing the compounds of the present invention. Compounds of the present invention are useful in the treatment of various inflammatory, autoimmune, and allergic diseases, such as methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, wound healing disorders, pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by the over-expression and over-activation of a matrix metalloproteinase.

Abstract: The present invention relates to ?-hydroxy and amino-substituted carboxylic acids, which act as matrix metalloproteinase inhibitors, particularly diastereomerically pure ?-hydroxy carboxylic acids, corresponding processes for their synthesis, and pharmaceutical compositions containing the compounds of the present invention. Compounds of the present invention are useful in the treatment of various inflammatory, autoimmune, and allergic diseases, such as methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, wound healing disorders, pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by the over-expression and over-activation of a matrix metalloproteinase.

Abstract: The present invention relates to ?-hydroxy and amino-substituted carboxylic acids, which act as matrix metalloproteinase inhibitors, particularly diastereomerically pure ?-hydroxy carboxylic acids, corresponding processes for their synthesis, and pharmaceutical compositions containing the compounds of the present invention. Compounds of the present invention are useful in the treatment of various inflammatory, autoimmune, and allergic diseases, such as methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, wound healing disorders, pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by the over-expression and over-activation of a matrix metalloproteinase.

Abstract: The present invention relates to ?-hydroxy and amino-substituted carboxylic acids, which act as matrix metalloproteinase inhibitors, particularly diastereomerically pure ?-hydroxy carboxylic acids, corresponding processes for their synthesis, and pharmaceutical compositions containing the compounds of the present invention. Compounds of the present invention are useful in the treatment of various inflammatory, autoimmune, and allergic diseases, such as methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, wound healing disorders, pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by the over-expression and over-activation of a matrix metalloproteinase.

Abstract: The present invention relates to ?-hydroxy and amino substituted carboxylic acids, which act as matrix metalloprotease inhibitors, particularly diastereomerically pure ?-hydroxy carboxylic acids, corresponding processes for the synthesis of and pharmaceutical compositions containing the compounds of the present invention. Compounds of the present invention are useful in the treatment of various inflammatory, autoimmune and allergic diseases, such as methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, wound healing disorders, pulmonary inflammation, acute respiratory distress syndrome, periodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by the over-expression and over-activation of a matrix metalloproteinase using the compounds.

Abstract: A plurality of flow network elements monitors network flows at the subscriber level for a plurality of subscribers. The flow network elements export flow records to a collector, which organizes the flow records. A policy client correlates the flow records and determines whether any network flows are violating a flow policy definition. If a flow policy definition is violated, the policy client transmits a policy action to a policy server which indicates what action to take for a given violating flow. The policy server assigns a flow policy for the subscriber corresponding with the violating flow. The assigned flow policy is then transmitted to the flow network element having that violating flow, and that flow network element installs the flow policy.

Abstract: A plurality of flow network elements monitors network flows at the subscriber level for a plurality of subscribers. The flow network elements export flow records to a collector, which organizes the flow records. A policy client correlates the flow records and determines whether any network flows are violating a flow policy definition. If a flow policy definition is violated, the policy client transmits a policy action to a policy server which indicates what action to take for a given violating flow. The policy server assigns a flow policy for the subscriber corresponding with the violating flow. The assigned flow policy is then transmitted to the flow network element having that violating flow, and that flow network element installs the flow policy.

Abstract: A plurality of flow network elements monitors network flows at the subscriber level for a plurality of subscribers. The flow network elements export flow records to a collector, which organizes the flow records. A policy client correlates the flow records and determines whether any network flows are violating a flow policy definition. If a flow policy definition is violated, the policy client transmits a policy action to a policy server which indicates what action to take for a given violating flow. The policy server assigns a flow policy for the subscriber corresponding with the violating flow. The assigned flow policy is then transmitted to the flow network element having that violating flow, and that flow network element installs the flow policy.

Abstract: The present invention relates to ?-hydroxy and amino substituted carboxylic acids, which act as matrix metalloprotease inhibitors, particularly diastereomerically pure ?-hydroxy carboxylic acids, corresponding processes for the synthesis of and pharmaceutical compositions containing the compounds of the present invention. Compounds of the present invention are useful in the treatment of various inflammatory, autoimmune and allergic diseases, such as methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, wound healing disorders, pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by the over-expression and over-activation of a matrix metalloproteinase using the compounds.