Abstract: The present invention relates to a composition for treating keratin fibers such as hair, comprising: (a) at least one hydroxy acid or salt thereof; (b) at least one cationic polyamino acid; and (c) water, wherein the amount of the (b) cationic polyamino acid(s) is 0.2% by weight or more, preferably 0.3% by weight or more, more preferably 0.5% by weight or more, and even more preferably 0.8% by weight or more, relative to the total weight of the composition. The present invention can smoothen keratin fibers.

Abstract: The present invention relates to a process for treating keratin fibres, in particular human keratin fibres such as the hair, comprising: 1) a step of applying to the keratin fibres a composition comprising: a) one or more compounds chosen from urea and/or urea derivatives, b) one or more polyols, c) one or more amino silicones, 2) a step of heat treatment of the keratin fibres, the heat treatment step 2) preferably being after step 1). The present invention also relates to a composition that may be used in the process according to the invention.

Abstract: The disclosure relates to compositions and methods for treating keratin fibers. Compositions comprise part (A) comprising (a) at least one compound chosen from urea and urea derivatives; and part (B) comprising (b) at least one polyol compound. Methods comprise applying the composition to keratin fibers to provide long-lasting effects such as good curl definition and regularity, better movement and discipline, and/or good volume and frizz control. Kits comprising the composition are also disclosed.

Abstract: The present invention relates to a composition comprising at least one silicone acrylic copolymer and at least one hydrocarbon-based block copolymer. The present invention also relates to a process for treating keratin fibers using a composition comprising at least one silicone acrylic copolymer and at least one hydrocarbon-based block copolymer.

Abstract: The present invention relates to a composition comprising at least one silicone acrylic copolymer and at least one particular block copolymer. The present invention also relates to a process for treating keratin fibers using a composition comprising at least one silicone acrylic copolymer and at least one particular block copolymer.

Abstract: The present disclosure relates to hair treatment compositions comprising: (a) at least one reducing agent selected from thiol-based compounds, non-thiol-based compounds, and mixtures thereof; (b) at least one non-polymeric and non-thiol, mono-, di-, and/or tri-carboxylic acid, and/or a salt thereof; (c) at least one alkaline agent; and (d) optionally, at least one cationic surfactant; wherein the pH of the composition is from about 2 to less than 7. The disclosure also relates to methods for imparting hair care benefits to the hair such as straightening effects, volume reduction, frizz control, manageability, cosmeticity and smooth feel, in addition to conditioning benefits.

Abstract: The present invention relates to a composition comprising: (a) one more compound(s) of thiolactone type, and (b) one or more silicones.

Abstract: The present invention relates to a composition comprising: (a) at least one compound of thiolactone type, and (b) one or more solvents, which may be identical or different, chosen from polar (non-)protic organic solvents; the pH of said composition being less than or equal to 7.

Abstract: The disclosure relates to compositions and methods for treating keratin fibers. Compositions comprise part (A) comprising (a) at least one compound chosen from urea and urea derivatives; and part (B) comprising (b) at least one polyol compound. Methods comprise applying the composition to keratin fibers to provide long-lasting effects such as good curl definition and regularity, better movement and discipline, and/or good volume and frizz control. Kits comprising the composition are also disclosed.

Abstract: The present invention relates to a process for treating keratin fibres, in particular human keratin fibres such as the hair, comprising: 1) a step of applying to the keratin fibres a composition comprising: a) one or more compounds chosen from urea and/or urea derivatives, b) one or more polyols, c) one or more amino silicones, 2) a step of heat treatment of the keratin fibres, the heat treatment step 2) preferably being after step 1). The present invention also relates to a composition that may be used in the process according to the invention.

Abstract: A method for preparing a pyrazole of formula (I) in which R,R? and R? have different meanings, characterised in that it involves reacting a sydnone of formula (II) in which R and R? have the meanings already indicated, with an alkyne of formula (III) in which R? has the meaning already indicated, in the presence of copper, to obtain a pyrazole compound of formula (I) that is then isolated and salified if desired.

Abstract: A method for preparing a pyrazole of formula (I) in which R,R? and R? have different meanings, characterised in that it involves reacting a sydnone of formula (II) in which R and R? have the meanings already indicated, with an alkyne of formula (III) in which R? has the meaning already indicated, in the presence of copper, to obtain a pyrazole compound of formula (I) that is then isolated and salified if desired.

Abstract: Azides of formula (I) in which V and W represent, independent of each other, a heterocycle comprising a copper-complexing nitrogen or sulphur heteroatom, said heterocycle being saturated or unsaturated, X and Y represent, independent of each other, a spacer moiety; Z represents a spacer moiety, F and F2 represent, independent of each other, a hydrogen atom or a functional moiety allowing the coupling of the azide of formula I with a chemical molecule, a biomolecule, a nanoparticle or a polymer, it being understood that at least one of F1 and F2 represents a functional moiety, methods of production and uses of same.

Abstract: Process for the preparation of compounds of formula (IV): wherein R1-R6 are as defined in the specification. Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.

Abstract: Process for the preparation of compounds of formula (IV): wherein R1-R6 are as defined in the specification. Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.

Abstract: Process for the preparation of compounds of formula (IV): wherein R1, R2, R3 and R4, which may be identical or different, each represent a hydrogen atom, a linear or branched (C1-C6)alkyl group, a linear or branched (C1-C6)alkoxy group, a fluorine atom, a chlorine atom, a protected amine group, a protected hydroxyl group, an alkoxycarbonyl group in which the alkoxy group is linear or branched (C1-C6), or a CF3 group, or R1?R4?H and R2 and R3 together with the carbon atoms carrying them form a 1,3-dioxolane group, R5 represents a saturated or unsaturated, linear or branched (C1-C6)alkyl group, a linear or branched (C1-C6)hydroxyalkyl group in which the hydroxyl function is protected, or a CO2R7 group in which R7 is a linear or branched (C1-C6)alkyl group, R6 represents a cyano group or a CO2R8 group in which R8 is a linear or branched (C1-C6)-alkyl group. Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.

Abstract: Process for the preparation of compounds of formula (IV): wherein R1, R2, R3 and R4, which may be identical or different, each represent a hydrogen atom, a linear or branched (C1-C6)alkyl group, a linear or branched (C1-C6)alkoxy group, a fluorine atom, a chlorine atom, a protected amine group, a protected hydroxyl group, an alkoxycarbonyl group in which the alkoxy group is linear or branched (C1-C6), or a CF3 group, or R1?R4?H and R2 and R3 together with the carbon atoms carrying them form a 1,3-dioxolane group, R5 represents a saturated or unsaturated, linear or branched (C1-C6)alkyl group, a linear or branched (C1-C6)hydroxyalkyl group in which the hydroxyl function is protected, or a CO2R7 group in which R7 is a linear or branched (C1-C6)alkyl group, R6 represents a cyano group or a CO2R8 group in which R8 is a linear or branched (C1-C6)-alkyl group. Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.