Patents by Inventor Manshu Tang

Manshu Tang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GALACTOKINASE INHIBITORS
    Publication number: 20230158025
    Abstract: Described herein are compounds that inhibit galactokinase (GALK) and other kinases and methods for producing the same. Also described are methods for using Structure-Activity Relationships (SAR) to develop compounds with enhanced activity.
    Type: Application
    Filed: April 22, 2021
    Publication date: May 25, 2023
    Inventors: Li Lui, Ya-qin Zhang, Surendra Karavadhi, Juan Marugan, Matthew Hall, Min Shen, Samarjit Patnaik, Kent Lai, Manshu Tang, Francis G. Whitby, Christopher P. Hill, Bijina Balakrishna
  • Galactokinase inhibitors for the treatment and prevention of associated diseases and disorders
    Patent number: 10471061
    Abstract: Disclosed are inhibitors of human galactokinase of formula (I) that are useful in treating or preventing a galactokinase mediated disease or disorder, e.g., galactosemia. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one inhibitor of the invention, and a method of treating or preventing such disease or disorder in a mammal. Formula (I).
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: November 12, 2019
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, University of Utah Research Foundation
    Inventors: Matthew B. Boxer, Martin J. Walsh, Li Liu, Cordelle D. Tanega, Min Shen, Kent Lai, Manshu Tang, Douglas S. Auld
  • GALACTOKINASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF ASSOCIATED DISEASES AND DISORDERS
    Publication number: 20190030031
    Abstract: Disclosed are inhibitors of human galactokinase of formula (I) that are useful in treating or preventing a galactokinase mediated disease or disorder, e.g., galactosemia. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one inhibitor of the invention, and a method of treating or preventing such disease or disorder in a mammal. Formula (I).
    Type: Application
    Filed: October 5, 2018
    Publication date: January 31, 2019
    Inventors: Matthew B. Boxer, Martin J. Walsh, Li Liu, Cordelle D. Tanega, Min Shen, Kent Lai, Manshu Tang, Douglas S. Auld
  • GALACTOKINASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF ASSOCIATED DISEASES AND DISORDERS
    Publication number: 20170035760
    Abstract: Disclosed are inhibitors of human galactokinase of formula (1) that are useful in treating or preventing a galactokinase mediated disease or disorder, e.g., galactosemia. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one inhibitor of the invention, and a method of treating or preventing such disease or disorder in a mammal. Formula (I).
    Type: Application
    Filed: August 11, 2016
    Publication date: February 9, 2017
    Inventors: Matthew B. Boxer, Martin J. Walsh, Li Liu, Cordelle D. Tanega, Min Shen, Kent Lai, Manshu Tang, Douglas S. Auld
  • Galactokinase inhibitors for the treatment and prevention of associated diseases and disorders
    Patent number: 9447087
    Abstract: Disclosed are inhibitors of human galactokinase of formula (1) that are useful in treating or preventing a galactokinase mediated disease or disorder, e.g., galactosemia. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one inhibitor of the invention, and a method of treating or preventing such disease or disorder in a mammal. Formula (I).
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: September 20, 2016
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Matthew B. Boxer, Martin J. Walsh, Li Liu, Cordelle D. Tanega, Min Shen, Kent Lai, Manshu Tang, Douglas S. Auld
  • GALACTOKINASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF ASSOCIATED DISEASES AND DISORDERS
    Publication number: 20140288100
    Abstract: Disclosed are inhibitors of human galactokinase of formula (1) that are useful in treating or preventing a galactokinase mediated disease or disorder, e.g., galactosemia. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one inhibitor of the invention, and a method of treating or preventing such disease or disorder in a mammal.
    Type: Application
    Filed: September 23, 2011
    Publication date: September 25, 2014
    Applicants: University of Utah Research Foundation, The United States of American, as Represented by the Decretary, Department of Health and Human
    Inventors: Matthew B. Boxer, Martin J. Walsh, Li Liu, Cordelle D. Tanega, Min Shen, Kent Lai, Manshu Tang, Douglas S. Auld
  • Galactokinase inhibitors
    Patent number: 8357701
    Abstract: Therapeutic agents for treatment of Galactosemia and disorders thereof, and other enzyme related disorders thereof are identified. The compounds inhibit galactokinase (GALK) and other kinase activity and are identified by a high throughput screening assay.
    Type: Grant
    Filed: August 14, 2008
    Date of Patent: January 22, 2013
    Assignee: University of Miami
    Inventors: Kent Lai, Klass Jan Wierenga, Manshu Tang
  • GALACTOKINASE INHIBITORS
    Publication number: 20110251236
    Abstract: Therapeutic agents for treatment of Galactosemia and disorders thereof, and other enzyme related disorders thereof are identified. The compounds inhibit galactokinase (GALK) and other kinase activity and are identified by a high throughput screening assay.
    Type: Application
    Filed: August 14, 2008
    Publication date: October 13, 2011
    Applicant: University of Miami
    Inventors: Kent Lai, Klass Jan Wierenga, Manshu Tang