Patents by Inventor Mansoureh BARZEGAR

Mansoureh BARZEGAR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COVID-19 THERAPEUTICS AND METHODS OF TREATMENT
    Publication number: 20220409637
    Abstract: Therapeutics and methods of treating COVID-19 in a patient in need thereof comprising administering a pharmaceutically effective dose of a therapeutic, wherein the therapeutic contains an ACE2 externalizer, and the ACE2 externalizer is one of diminazene, diminazene aceturate, or a pharmaceutically acceptable salt, solvate, ester, amide, clathrate, stereoisomer, enantiomer, or prodrug thereof.
    Type: Application
    Filed: September 6, 2022
    Publication date: December 29, 2022
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Johnathan Steven ALEXANDER, Christopher KEVIL, Mansoureh BARZEGAR, Ana Maria DRAGOI
  • CULTURE MODIFICATIONS OF STEM CELLS TO ENHANCE THERAPEUTIC RECOVERY FROM TISSUE DAMAGE AND ISCHEMIA-REPERFUSION INJURY AND DELAYED ORGAN FUNCTION
    Publication number: 20220049224
    Abstract: Therapeutics comprising Cells and methods of creating enhanced human Placenta Mesenchymal Stem Cells (hPMSCs) comprising culturing the hPMSCs with cholesterol for one of between 24 and 96 hours and between 48 and 72 hours. Therapeutics comprising microparticles and methods of creating enhanced microparticles from hPMSCs comprising culturing the hPMSCs with cholesterol for one of between 24 and 96 hours and between 48 and 72 hours, and then separating the enhanced microparticles from the hPMSCs. Therapeutics comprising exosomes and methods of creating enhanced exosomes from hPMSCs comprising culturing the hPMSCs with cholesterol for one of between 24 and 96 hours and between 48 and 72 hours, and then separating the enhanced microparticles from the hPMSCs. Therapeutic comprising extracellular vesicles and methods of creating enhanced EVs from hPMSCs comprising culturing the hPMSCs with cholesterol for one of between 24 and 96 hours and between 48 and 72 hours.
    Type: Application
    Filed: October 30, 2020
    Publication date: February 17, 2022
    Inventors: Jonathan ALEXANDER, Mansoureh BARZEGAR, Yuping WANG
  • USE OF IMMORTALIZED PLACENTAL STEM CELLS IPSC/EXTRACELLULAR VESICLES TO ENHANCE THERAPEUTIC RECOVERY FROM TISSUE DAMAGE AND ISCHEMIA-REPERFUSION INJURY AND DELAYED ORGAN FUNCTION
    Publication number: 20210401898
    Abstract: Therapeutics and methods for treating a stroke in a human comprising administering a therapeutic to the patient, wherein the therapeutic comprises one of immortalized human placenta mesenchymal stem cells (hPMSCs) and a product from the immortalized hPMSCs. Methods and therapeutic products comprising extracellular vesicles (EVs) isolated from of immortalized hPMSCs. Therapeutics and methods of treating COVID-19 disease vascular injury comprising administering a therapeutic to the patient, wherein the therapeutic comprises one of hPMSCs and a product from the hPMSCs.
    Type: Application
    Filed: April 12, 2021
    Publication date: December 30, 2021
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Johnathan Steven ALEXANDER, Mansoureh BARZEGAR, Yuping WANG, Anthony Wayne ORR, Mabruka ALFAIDI
  • COVID-19 THERAPEUTICS AND METHODS OF TREATMENT
    Publication number: 20210346409
    Abstract: Therapeutics and methods of treating COVID-19 in a patient in need thereof comprising administering a pharmaceutical composition containing a pharmaceutically effective dose of a therapeutic, wherein the therapeutic contains both an ACE2 externalizer and one or more ACE2 internalization preventors. Methods of treatment and pharmaceutical compositions comprising an ACE2 externalizer and one or more ACE2 internalization preventors.
    Type: Application
    Filed: May 7, 2021
    Publication date: November 11, 2021
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Johnathan Steven ALEXANDER, Christopher KEVIL, Mansoureh BARZEGAR, Ana Maria DRAGOI
  • INTRAPERITONEAL INJECTION OF HUMAN PLACENTA STEM CELLS PROTECT THE BRAIN FROM STROKE INJURY VIA EXOSOME/MICROPARTICLE FORMATION AND ACE2 MAINTENANCE OF BRAIN PERFUSION
    Publication number: 20210030806
    Abstract: Therapeutics and methods of treating a stroke in a patient comprising delivering stem cells into a peritoneum of the patent. According to a further embodiment the stem cells are mesenchymal stem cells. According to a further embodiment the stem cells are human placenta mesenchymal stem cells (hPMSC). According to a further embodiment the stroke is one of stroke is one of occlusive, post-occlusive, hemorrhagic, and transient ischemic injury. According to a further embodiment the method further comprises the step of delivering a clot busting compound into a blood stream of the patient.
    Type: Application
    Filed: March 30, 2020
    Publication date: February 4, 2021
    Inventors: Jonathan ALEXANDER, Mansoureh BARZEGAR, Yuping WANG