Patents by Inventor Mansukh Wani

Mansukh Wani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7-Substituted camptothecin and camptothecin analogs and methods for producing the same
    Publication number: 20050209263
    Abstract: Methods of forming camptothecin compounds which are effective anti-tumor compounds are disclosed. These compounds inhibit the enzyme topoisomerase I and may alkylate DNA of the associated topoisomerase I-DNA cleavable complex.
    Type: Application
    Filed: May 17, 2005
    Publication date: September 22, 2005
    Applicant: Research Triangle Insitute
    Inventors: Mansukh Wani, Govindarajan Manikumar, Monroe Wall, Michael Wall
  • Camptothecin analogs having an E-ring ketone
    Publication number: 20050096338
    Abstract: Camptothecin analogs having an E-ring ketone are effective anti tumor compounds. These compounds inhibit the enzyme topoisomerase I and may alkylate DNA of the associated topoisomerase I DNA cleavable complex.
    Type: Application
    Filed: December 17, 2004
    Publication date: May 5, 2005
    Applicant: Research Triangle Institute
    Inventors: Monroe Wall, Mansukh Wani, Govindarajan Manikumar, Michael Wall
  • Camptothecin analogs as potent inhibitors of topoisomerase I
    Patent number: 5106742
    Abstract: A method for synthesizing camptothecin and camptothecin analogs using a novel hydroxyl-containing tricyclic intermediate and the camptothecin analogs produced by the process. The camptothecin analogs are effective inhibitors of topoisomerase I and show anti-leukemic and anti-tumor activity.
    Type: Grant
    Filed: October 23, 1989
    Date of Patent: April 21, 1992
    Inventors: Monroe E. Wall, Mansukh Wani