Patents by Inventor Mansun Law

Mansun Law has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Engineered HCV E2 Immunogens and Related Vaccine Compositions
    Publication number: 20230034467
    Abstract: The present invention provides novel engineered HCV E2 polypeptide immunogens and related vaccine compositions that display the engineered E2 polypeptides. The invention also provides methods of using such immunogens and vaccine compositions in various therapeutic applications, e.g., for preventing or treating HCV infections.
    Type: Application
    Filed: December 17, 2021
    Publication date: February 2, 2023
    Inventors: Linling He, Jiang Zhu, Erick Giang, Mansun Law, Ian Wilson, Netanel Tzarum
  • Engineered HCV E2 immunogens and related vaccine compositions
    Patent number: 11008368
    Abstract: The present invention provides novel engineered HCV E2 polypeptide immunogens and related vaccine compositions that display the engineered E2 polypeptides. The invention also provides methods of using such immunogens and vaccine compositions in various therapeutic applications, e.g., for preventing or treating HCV infections.
    Type: Grant
    Filed: July 24, 2020
    Date of Patent: May 18, 2021
    Assignee: THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Linling He, Jiang Zhu, Erick Giang, Mansun Law, Ian Wilson, Netanel Tzarum
  • Engineered HCV E2 Immunogens and Related Vaccine Compositions
    Publication number: 20210024585
    Abstract: The present invention provides novel engineered HCV E2 polypeptide immunogens and related vaccine compositions that display the engineered E2 polypeptides. The invention also provides methods of using such immunogens and vaccine compositions in various therapeutic applications, e.g., for preventing or treating HCV infections.
    Type: Application
    Filed: July 24, 2020
    Publication date: January 28, 2021
    Inventors: Linling He, Jiang Zhu, Erick Giang, Mansun Law, Ian Wilson, Netanel Tzarum
  • AGENTS FOR HCV TREATMENT
    Publication number: 20110311550
    Abstract: Provided are polypeptides, including antibodies and fragments thereof, useful for preventing or treating new or recurring infection of hepatitis C virus, as well as methods of preventing or treating new or recurring hepatitis C viral infection. Also provided are modified E1 and E2 polypeptides.
    Type: Application
    Filed: October 23, 2009
    Publication date: December 22, 2011
    Applicant: The Scripps Research Institute
    Inventors: Mansun Law, Dennis R. Burton
  • HCV neutralizing epitopes
    Publication number: 20100104555
    Abstract: The invention relates to modified hepatitis C virus E2 polypeptides that are effective in eliciting the production of cross-neutralizing antibodies against hepatitis C virus. The invention provides modified hepatitis C virus E2 polypeptides, preparations and pharmaceutical compositions containing them, as well as methods for using these modified E2 polypeptides.
    Type: Application
    Filed: October 24, 2008
    Publication date: April 29, 2010
    Applicant: The Scripps Research Institute
    Inventors: Mansun Law, Toshiaki Maruyama, Dennis R. Burton, Jonathan K. Ball, Norman M. Kneteman
  • Anti-Viral Compositions
    Publication number: 20080299131
    Abstract: The invention provides a composition comprising for simultaneous, sequential or separate administration a) a polyanion; and b) an antibody reactive against an antigen on the surface of an intracellular form of a virus, which virus has an extracellular form that is surrounded by one lipid membrane more than the intracellular form. The present inventors have found that the compositions according to the invention comprising an antibody and a polyanion can neutralize virus infectivity more efficiently than other compositions reported hitherto.
    Type: Application
    Filed: June 28, 2005
    Publication date: December 4, 2008
    Applicant: IMPERIAL INNOVATIONS LIMITED
    Inventors: Geoffrey Lilley Smith, Gemma Chevonne Carter, Mansun Law, Michael Stanley Hollinshead