Patents by Inventor Manu De Groeve

Manu De Groeve has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the production of immunoglobulin single variable domains
    Patent number: 11851480
    Abstract: Methods are provided for the manufacture of polypeptides comprising at least one immunoglobulin variable domain that result in an increased yield. The methods are based on simultaneous enhancement of one or more auxiliary proteins in the host.
    Type: Grant
    Filed: July 30, 2020
    Date of Patent: December 26, 2023
    Assignee: Ablynx N.V.
    Inventors: Peter Schotte, Manu De Groeve
  • Method for the production of immunoglobulin single variable domains
    Patent number: 10975141
    Abstract: Methods are provided for the manufacture of polypeptides comprising at least one immunoglobulin variable domain that result in an increased yield. The methods are based on simultaneous enhancement of one or more auxiliary proteins in the host.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: April 13, 2021
    Assignee: Ablynx N.V.
    Inventors: Peter Schotte, Manu De Groeve
  • METHOD FOR THE PRODUCTION OF IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS
    Publication number: 20210047392
    Abstract: Methods are provided for the manufacture of polypeptides comprising at least one immunoglobulin variable domain that result in an increased yield. The methods are based on simultaneous enhancement of one or more auxiliary proteins in the host.
    Type: Application
    Filed: July 30, 2020
    Publication date: February 18, 2021
    Applicant: Ablynx N.V.
    Inventors: Peter Schotte, Manu De Groeve
  • METHOD FOR THE PRODUCTION OF IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS
    Publication number: 20190194302
    Abstract: Methods are provided for the manufacture of polypeptides comprising at least one immunoglobulin variable domain that result in an increased yield. The methods are based on simultaneous enhancement of one or more auxiliary proteins in the host.
    Type: Application
    Filed: February 10, 2017
    Publication date: June 27, 2019
    Applicant: Ablynx N.V.
    Inventors: Peter SCHOTTE, Manu DE GROEVE
  • Lactose phosphorylase enzymes
    Patent number: 8278073
    Abstract: The present invention relates to novel lactose phosphorylase enzymes and the uses thereof. More specifically, the invention relates to lactose phosphorylase enzymes created by mutation of a cellobiose phosphorylase from Cellulomonas uda. By introducing mutations in this enzyme, the activity can be switched from cellobiose phosphorylase into lactose phosphorylase.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: October 2, 2012
    Assignee: Universiteit Gent
    Inventors: Tom Desmet, Manu De Groeve, Wim Soetaert
  • NOVEL LACTOSE PHOSPHORYLASE ENZYMES
    Publication number: 20110008849
    Abstract: The present invention relates to novel lactose phosphorylase enzymes and the uses thereof. More specifically, the invention relates to lactose phosphorylase enzymes created by mutation of a cellobiose phosphorylase from Cellulomonas uda. By introducing mutations in this enzyme, the activity can be switched from cellobiose phosphorylase into lactose phosphorylase.
    Type: Application
    Filed: December 19, 2008
    Publication date: January 13, 2011
    Inventors: Tom Desmet, Manu De Groeve, Wim Soetaert