Patents by Inventor Manu Thomas Kalathottukaren

Manu Thomas Kalathottukaren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antithrombotic compounds, methods and uses thereof
    Patent number: 10584243
    Abstract: Provided herein are polymers and methods for their use in binding a phosphate containing biological macromolecules. Specifically, the methods and uses provided herein may be used to inhibit thrombin binding to polyphosphate or as an antithrombotic agent for the treatment of stroke, acute coronary syndrome, pulmonary embolism, atrial fibrillation, venous and arterial thromboembolism, disseminated intravascular coagulation (DIC), deepvein thrombosis (DVT), peripheral artery disease, trauma-induced coagulopathy, extracorporeal circulation, cancer-associated thrombosis, sepsis, septic shock, Systemic Inflammatory Response Syndrome (SIRS), or inflammation.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: March 10, 2020
    Assignees: The University of British Columbia, The Board of Trustees of the University of Illinois
    Inventors: Jayachandran Kizhakkedathu, James H. Morrissey, Richard J. Travers, Rajesh Shenoi, Manu Thomas Kalathottukaren
  • Antithrombotic Compounds, Methods and Uses Thereof
    Publication number: 20190203047
    Abstract: Provided herein are polymers and methods for their use in binding a phosphate containing biological macromolecules. Specifically, the methods and uses provided herein may be used to inhibit thrombin binding to polyphosphate or as an antithrombotic agent for the treatment of stroke, acute coronary syndrome, pulmonary embolism, atrial fibrillation, venous and arterial thromboembolism, disseminated intravascular coagulation (DIC), deepvein thrombosis (DVT), peripheral artery disease, trauma-induced coagulopathy, extracorporeal circulation, cancer-associated thrombosis, sepsis, septic shock, Systemic Inflammatory Response Syndrome (SIRS), or inflammation.
    Type: Application
    Filed: December 19, 2018
    Publication date: July 4, 2019
    Inventors: Jayachandran Kizhakkedathu, James H. Morrissey, Richard J. Travers, Rajesh Shenoi, Manu Thomas Kalathottukaren
  • Antithrombotic compounds, methods and uses thereof
    Patent number: 10202507
    Abstract: Provided herein are polymers and methods for their use in binding a phosphate containing biological macromolecules. Specifically, the methods and uses provided herein may be used to inhibit thrombin binding to polyphosphate or as an antithrombotic agent for the treatment of stroke, acute coronary syndrome, pulmonary embolism, atrial fibrillation, venous and arterial thromboembolism, disseminated intravascular coagulation (DIC), deep-vein thrombosis (DVT), peripheral artery disease, trauma-induced coagulopathy, extracorporeal circulation, cancer-associated thrombosis, sepsis, septic shock, Systemic Inflammatory Response Syndrome (SIRS), or inflammation.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: February 12, 2019
    Assignees: The University of British Columbia, The Board of Trustees of the University of Illinois
    Inventors: Jayachandran Kizhakkedathu, James H. Morrissey, Richard J. Travers, Rajesh Shenoi, Manu Thomas Kalathottukaren
  • Antithrombotic Compounds, Methods and Uses Thereof
    Publication number: 20170233573
    Abstract: Provided herein are polymers and methods for their use in binding a phosphate containing biological macromolecules. Specifically, the methods and uses provided herein may be used to inhibit thrombin binding to polyphosphate or as an antithrombotic agent for the treatment of stroke, acute coronary syndrome, pulmonary embolism, atrial fibrillation, venous and arterial thromboembolism, disseminated intravascular coagulation (DIC), deep-vein thrombosis (DVT), peripheral artery disease, trauma-induced coagulopathy, extracorporeal circulation, cancer-associated thrombosis, sepsis, septic shock, Systemic Inflammatory Response Syndrome (SIRS), or inflammation.
    Type: Application
    Filed: May 29, 2015
    Publication date: August 17, 2017
    Inventors: Jayachandran Kizhakkedathu, James H. Morrissey, Richard J. Travers, Rajesh Shenoi, Manu Thomas Kalathottukaren