Abstract: A method of additively manufacturing three-dimensional objects, and/or a method of controlling one or more irradiation parameters of the energy beam system, may include determining an irradiation setting using an irradiation control model and outputting an irradiation control command to an energy beam system based at least in part on the irradiation setting. The irradiation control model may be configured to determine the irradiation setting based at least in part on a power density factor and/or an irradiation vector factor. The irradiation control command may be configured to change one or more irradiation parameters for additively manufacturing a three-dimensional object. An additive manufacturing system may include an energy beam system and a control system that includes an irradiation controller. The irradiation controller may include a control module configured to perform such a method.

Abstract: The present invention relates to a formulation of Ivermectin in oral solution which allows proper absorption, enabling the drug to be consumed at any time. In particular, the oral lipid composition is designed with the appropriate selection of a medium-chain triglyceride oil, a hydrophilic cosolvent and an antioxidant, so as to influence the absorption/digestibility of the poorly water-soluble active ingredient and facilitate bioavailability and bioactivity for the administration of the oral solution in drops. The formulation includes Ivermectin in a lipid medium including a cosolvent and an antioxidant in combination with an oily solvent to form an oral solution for administration in drops. The field of the invention is related to improving the bioavailability of insoluble drugs such as Ivermectin for administration in oral drop forms based mainly on lipids without compromising stability or creating impurities.

Abstract: A nickel-based superalloy is provided, which includes: 5.6 wt % to 6.6 wt % aluminum; 6.0 wt % to 9.0 wt % tantalum; 4.0 wt % to 7.0 wt % chromium; 4.0 wt % to 7.0 wt % tungsten; 0.5 wt % to 2.5 wt % molybdenum; 1.5 wt % to 5.5 wt % rhenium; 7.0 wt % to 13.0 wt % cobalt; 0.1 wt % to 0.7 wt % hafnium; 0.001 wt % to 0.005 wt % carbon; 0.002 wt % to 0.05 wt % boron; up to 0.1 wt % yttrium; and a balance of nickel and incidental impurities, wherein the composition exhibits a rupture life that is greater than 80 hours at 1093.3° C. and 20 ksi and an oxidation resistance of less than 25.4 ?m surface loss at 1176.7° C. after a 400 hour Mach I test. Components are also provided formed from such a nickel-based superalloy.

Abstract: Methods and apparatus for two-dimensional and three-dimensional scanning path visualization are disclosed. An example apparatus includes at least one memory, instructions in the apparatus, and processor circuitry to execute the instructions to identify at least one melt pool dimension using a beam parameter setting, the at least one melt pool dimension identified from a plurality of melt pool dimensions obtained by varying the beam parameter setting, identify a response surface model based on the plurality of melt pool dimensions to determine an effect of variation in the beam parameter setting on the at least one melt pool dimension, output a three-dimensional model of a scanning path for an additive manufacturing process using the response surface model, and adjust the beam parameter setting based on the three-dimensional model to identify a second beam parameter setting.

Abstract: A bonded part includes: a substrate including a polymer matrix material; a metal layer; a layer of adhesive between the substrate and the metal layer; and a layer of smut between the layer of adhesive and the metal layer.

Abstract: Methods for creating a cast component, along with the resulting cast components, are provided. The method may provide for a controlled grain structure in the resulting cast component. The methods may include heating at least a first portion mold under controlled conditions, such as when the first portion of the mold is buried in a ceramic powder.

Abstract: Methods and apparatus for two-dimensional and three-dimensional scanning path visualization are disclosed. An example apparatus includes a parameter determiner to determine at least one of a laser beam parameter setting or an electron beam parameter setting, a melt pool geometry determiner to identify melt pool dimensions using the parameter setting, the melt pool geometry determiner to vary the parameter setting to obtain multiple melt pool dimensions, and a visualization path generator to generate a three-dimensional view of a scanning path for an additive manufacturing process using the identified melt pool dimensions. The visualization path generator adjusts the laser beam parameters based on the generated three-dimensional view.

Abstract: Methods of simulating additively manufacturing an object may include generating a simulated additively manufactured object based at least in part on a plurality of approximate consolidation domains that respectively correspond to a plurality of consolidation tracks determined from one or more digital representations of an additively manufactured object, and determining a predictive inference with respect to one or more material properties of the object to be additively manufactured based at least in part on the simulated additively manufactured object. Methods may include generating, for an object to be additively manufactured, a CAD file and/or a build file based at least in part on a simulated additively manufactured object and/or based at least in part on one or more predictive inferences with respect to one or more material properties of the object to be additively manufactured.

Abstract: A method of additively manufacturing three-dimensional objects, and/or a method of controlling one or more irradiation parameters of the energy beam system, may include determining an irradiation setting using an irradiation control model and outputting an irradiation control command to an energy beam system based at least in part on the irradiation setting. The irradiation control model may be configured to determine the irradiation setting based at least in part on a power density factor and/or an irradiation vector factor. The irradiation control command may be configured to change one or more irradiation parameters for additively manufacturing a three-dimensional object. An additive manufacturing system may include an energy beam system and a control system that includes an irradiation controller. The irradiation controller may include a control module configured to perform such a method.

Abstract: Methods and apparatus for two-dimensional and three-dimensional scanning path visualization are disclosed. An example apparatus includes a parameter determiner to determine at least one of a laser beam parameter setting or an electron beam parameter setting, a melt pool geometry determiner to identify melt pool dimensions using the parameter setting, the melt pool geometry determiner to vary the parameter setting to obtain multiple melt pool dimensions, and a visualization path generator to generate a three-dimensional view of a scanning path for an additive manufacturing process using the identified melt pool dimensions, the visualization path generator to adjust the laser beam parameters based on the generated three-dimensional view.

Abstract: Methods for creating a cast component, along with the resulting cast components, are provided. The method may provide for a controlled grain structure in the resulting cast component. The methods may include heating at least a first portion mold under controlled conditions, such as when the first portion of the mold is buried in a ceramic powder.

Abstract: A bonded part includes: a substrate including a polymer matrix material; a metal layer; a layer of adhesive between the substrate and the metal layer; and a layer of smut between the layer of adhesive and the metal layer.

Abstract: A part that includes a metal layer positioned on it. The part includes a composite core. A metal layer is positioned on the composite core such that the layer of adhesive is sandwiched between the composite core and the metal layer. A layer of smut that is positioned between the layer of adhesive and the metal layer.

Abstract: An apparatus for electro-polishing an object that has a complex shape that defines a cavity. The apparatus includes an electrode that is configured to closely engage a predetermined location of the object. The electrode is configured to be electrically connected to a power supply.

Abstract: An apparatus for electro-polishing an object that has a complex shape that defines a cavity. The apparatus includes an electrode that is configured to closely engage a predetermined location of the object. The electrode is configured to be electrically connected to a power supply.

Abstract: A part that includes a metal layer positioned on it. The part includes a composite core. A metal layer is positioned on the composite core such that the layer of adhesive is sandwiched between the composite core and the metal layer. A layer of smut that is positioned between the layer of adhesive and the metal layer.

Abstract: A new and distinct cultivar of Passion Fruit plant named ‘Grand Passion’ is disclosed, characterized by its light satiny purple flower color, deep yellow fruit pulp color, and the balance between the acidity and brix presence in its pulp. The new variety is a Passiflora, normally used for outdoor ornamental purposes.