Abstract: The invention concerns treating Tauopathies such as Alzheimer’s disease with a SCO- Spondin derived peptide administered through a systemic route to the patient. Said peptide has amino acid sequence X1-W-S-A1-W-S-A2-C-S-A3-A4-C-G-X2, in which A1, A2, A3 and A4 consists of amino acid sequences consisting of 1 to 5 amino acids, X1 and X2 consists of amino acid sequences consisting of 1 to 6 amino acids, or X1 and X2 are absent; it being possible for the N-terminal amino acid to be acetylated, for the C-terminal amino acid to be amidated, or the N-terminal amino acid to be acetylated and the C-terminal amino acid to be amidated.

Abstract: The invention concerns treating non-brain nervous system injury, such as spinal cord injury and/or optic nerve injury, with a SCO-Spondin derived peptide administered through a systemic route to the patient. Said peptide has amino acid sequence X1-W-S-A1-W-S-A2-C-S-A3-A4-C-G-X2, in which A1, A2, A3 and A4 consists of amino acid sequences consisting of 1 to 5 amino acids, X1 and X2 consists of amino acid sequences consisting of 1 to 6 amino acids; or X1 and X2 are absent; it being possible for the N-terminal amino acid to be acetylated, for the C-terminal amino acid to be amidated, or the N-terminal amino acid to be acetylated and the C-terminal amino acid to be amidated. Also described the use of such peptides for remyelination.

Abstract: The present invention is related to arginine deiminase encapsulated into erythrocytes for use in therapy. It is in particular related to the use thereof in treating arginase-1 deficiency. Also, it relates to novel pharmaceutical compositions comprising arginine deiminase from M. arginini encapsulated into erythrocytes and the use thereof in treating diseases that may benefit from arginine depletion, such as arginine dependent cancers, in particular arginine-auxotrophic cancers, and arginase-1 deficiency.

Abstract: The present invention is related to arginine deiminase encapsulated into erythrocytes for use in therapy. It is in particular related to the use thereof in treating arginase-1 deficiency. Also, it relates to novel pharmaceutical compositions comprising arginine deiminase from M. arginini encapsulated into erythrocytes and the use thereof in treating diseases that may benefit from arginine depletion, such as arginine dependent cancers, in particular arginine-auxotrophic cancers, and arginase-1 deficiency.

Abstract: The present invention is related to arginine deiminase encapsulated into erythrocytes for use in therapy. It is in particular related to the use thereof in treating arginase-1 deficiency. Also, it relates to novel pharmaceutical compositions comprising arginine deiminase from M. arginini encapsulated into erythrocytes and the use thereof in treating diseases that may benefit from arginine depletion, such as arginine dependent cancers, in particular arginine-auxotrophic cancers, and arginase-1 deficiency.