Abstract: Compositions and methods for preparing and delivering encapsulated biologically active agents to specific cell types are disclosed. Substances can be encapsulated in the VP6 inner capsid protein of rotavirus and delivered to selected cells, tissues and organs. Targeting agents can be linked to the surface of the VP6 sphere so that appropriate agents can be delivered to preselected cells and tissue types.

Abstract: Advantage is taken of the ability of rotaviral VP6 protein to home to macrophage and monocytes to provide label to these cells in either an in vitro or in vivo environment. Further, the ability to couple label to the VP6 protein and to couple VP6 to a targeting agent provides a mechanism for conducting label (or an effector moiety) to any desired target.

Abstract: A hose construction, fastening member therefor and methods of making the same are provided, the hose construction comprising a tubular flexible hose having opposite ends and an outer peripheral surface, a fastening member, and a clamping unit fastened to one of the ends of the hose with the fastening member for substantially circumferentially and radially inwardly clamping the one end onto a member that has been inserted into the one end, the fastening member having a part thereof secured to the outer peripheral surface of the hose and having a recess therein that receives part of the clamping unit therein, the fastening member having snap-fit structure for holding the part of the clamping unit in the recess thereof before the fastening member is secured to the hose.

Abstract: A hose construction, fastening member therefor and methods of making the same are provided, the hose construction comprising a tubular flexible hose having opposite ends and an outer peripheral surface, a fastening member, and a clamping unit fastened to one of the ends of the hose with the fastening member for substantially circumferentially and radially inwardly clamping the one end onto a member that has been inserted into the one end, the fastening member having a part thereof secured to the outer peripheral surface of the hose and having a recess therein that receives part of the clamping unit therein, the fastening member having snap-fit structure for holding the part of the clamping unit in the recess thereof before the fastening member is secured to the hose.

Abstract: New chimeric proteins, DNA encoding the same, and the use of these proteins in stimulating immunity against respiratory diseases such as pneumonia, including shipping fever pneumonia, are disclosed. The chimeric proteins include at least one epitope of leukotoxin fused to an active fragment of a cytokine. The chimeric proteins can be used in a vaccine composition. Also disclosed are methods of vaccination as well as methods of making the proteins employed in the vaccines.

Abstract: New chimeric proteins, DNA encoding the same, and the use of these proteins in stimulating immunity against respiratory diseases such as pneumonia, including shipping fever pneumonia, are disclosed. The chimeric proteins include at least one epitope of leukotoxin fused to an active fragment of a cytokine. The chimeric proteins can be used in a vaccine composition. Also disclosed are methods of vaccination as well as methods of making the proteins employed in the vaccines.

Abstract: A hose construction, fastening member therefor and methods of making the same are provided, the hose construction comprising a tubular flexible hose having opposite ends and an outer peripheral surface, a fastening member, and a clamping unit fastened to one of the ends of the hose with the fastening member for substantially circumferentially and radially inwardly clamping the one end onto a member that has been inserted into the one end, the fastening member having a part thereof secured to the outer peripheral surface of the hose and having a recess therein that receives part of the clamping unit therein, the fastening member having snap-fit structure for holding the part of the clamping unit in the recess thereof before the fastening member is secured to the hose.

Abstract: A hose construction and method of making the same are provided, the hose construction comprising a tubular flexible hose having opposite ends, fastening structure, and a clamp fastened to one of the ends of the hose with the fastening structure for substantially circumferentially and radially inwardly clamping the one end onto a member that has been inserted into the one end, the clamp having end projections for being toggled together to circumferentially enlarge the clamp and hold the clamp out of its clamping condition and for being released from each other so as to be circumferentially moved apart from each other as the clamp circumferentially shrinks into its clamping condition by the natural spring force of the clamp, the fastening structure comprising a single spot of adhesive disposed between and against the clamp and the hose at a point on the hose that is located substantially diametrically opposite the point on the hose where the end projections of the clamp are adapted to be toggled together.

Abstract: Methods of treating diseases in swine are disclosed using porcine interferon alpha and/or gamma.

Abstract: A hose construction and method of making the same are provided, the hose construction comprising a tubular flexible hose having opposite ends, fastening structure, and a clamp fastened to one of the ends of the hose with the fastening structure for substantially circumferentially and radially inwardly clamping the one end onto a member that has been inserted into the one end, the clamp having end projections for being toggled together to circumferentially enlarge the clamp and hold the clamp out of its clamping condition and for being released from each other so as to be circumferentially moved apart from each other as the clamp circumferentially shrinks into its clamping condition by the natural spring force of the clamp, the fastening structure comprising a single spot of adhesive disposed between and against the clamp and the hose at a point on the hose that is located substantially diametrically opposite the point on the hose where the end projections of the clamp are adapted to be toggled together.