Patents by Inventor Manuel D'Eusebio
Manuel D'Eusebio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12287169Abstract: The installation includes a traversing portion configured to be rotatably mounted and supported on a stationary support structure, to rotate about a traversing axis. An elevating portion is rotatably supported by the traversing portion about an elevating axis perpendicular to the traversing axis. A firearm assembly supported by the elevating portion has a barrel configured to fire linkless ammunitions through firearm assembly. A magazine is configured to contain a plurality of linkless ammunitions to be fed to the barrel. A feeding assembly is configured to transfer the linkless ammunitions from the magazine to the barrel. The magazine is carried by the traversing portion and is operatively integral therewith. The feeding assembly is carried by the elevating portion and is operatively integral therewith. A transfer device mounted on the traversing portion is configured to transfer the linkless ammunitions (A) from the magazine to the feeding assembly.Type: GrantFiled: June 7, 2022Date of Patent: April 29, 2025Assignee: LEONARDO S.P.A.Inventors: Manuel D'Eusebio, Claudio Nardi, Luca Mineo
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Publication number: 20240280338Abstract: The installation includes a traversing portion configured to be rotatably mounted and supported on a stationary support structure, to rotate about a traversing axis. An elevating portion is rotatably supported by the traversing portion about an elevating axis perpendicular to the traversing axis. A firearm assembly supported by the elevating portion has a barrel configured to fire linkless ammunitions through firearm assembly. A magazine is configured to contain a plurality of linkless ammunitions to be fed to the barrel. A feeding assembly is configured to transfer the linkless ammunitions from the magazine to the barrel. The magazine is carried by the traversing portion and is operatively integral therewith. The feeding assembly is carried by the elevating portion and is operatively integral therewith. A transfer device mounted on the traversing portion is configured to transfer the linkless ammunitions (A) from the magazine to the feeding assembly.Type: ApplicationFiled: June 7, 2022Publication date: August 22, 2024Inventors: Manuel D'EUSEBIO, Claudio NARDI, Luca MINEO
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Patent number: 11918301Abstract: The invention relates to a goniometer that enables precise marking of the desired ocular axis in the phase immediately after surgery for the treatment of astigmatism. It essentially consists of two circular, transparent discs, one of which is at least axially stationary, in which the angles from 0° to 180° are marked, which are aligned with the angles from 0° to 180° of the patient's eye; and the other one of which is movable both angularly and axially, with a reference mark (9) and moving rigidly connected to a marking part (12), impregnated with die, which is responsible for marking the eye. Not only does the device make it possible to carry out said marking in a precise and comfortable manner, it also makes it possible to measure the angle of toric lenses already implanted.Type: GrantFiled: May 31, 2019Date of Patent: March 5, 2024Assignee: UNIVERSIDAD DE MALAGInventors: Manuel D Marin Granados, Oscar D De Cozar Macias, Juan Antonio Bascunana Pareja, Joaquin Fernandez Cabrera, Salvador Nebro Cobos
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Publication number: 20230414554Abstract: The present invention relates to compounds, compositions, and combined preparations for the treatment of hepatocellular carcinoma, diagnostic methods, and methods for selecting therapeutic agents useful in the prevention, improvement, relief, and/or treatment of hepatocellular carcinoma.Type: ApplicationFiled: July 14, 2021Publication date: December 28, 2023Inventors: Juan Luis LOPEZ CANOVAS, Manuel D. GAHETE ORTIZ, Raul M. LUQUE HUERTAS, Mercedes DEL RIO MORENO, Justo CASTAÑO FUENTES, Manuel RODRÍGUEZ PERÁLVAREZ, Manuel DE LA MATA, Marina Esther SÁNCHEZ FRÍAS
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Publication number: 20210205024Abstract: The invention relates to a goniometer that enables precise marking of the desired ocular axis in the phase immediately after surgery for the treatment of astigmatism. It essentially consists of two circular, transparent discs, one of which is at least axially stationary, in which the angles from 0° to 180° are marked, which are aligned with the angles from 0° to 180° of the patient's eye; and the other one of which is movable both angularly and axially, with a reference mark (9) and moving rigidly connected to a marking part (12), impregnated with die, which is responsible for marking the eye. Not only does the device make it possible to carry out said marking in a precise and comfortable manner, it also makes it possible to measure the angle of toric lenses already implanted.Type: ApplicationFiled: May 31, 2019Publication date: July 8, 2021Inventors: Manuel D MARIN GRANADOS, Oscar D DE COZAR MACIAS, Juan Antonio BASCUNANA PAREJA, Joaquin FERNANDEZ CABRERA, Salvador NEBRO COBOS
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Publication number: 20200158732Abstract: The present invention relates to the use of levels of the amount or concentration of the ghrelin-O-acyltransferase (GOAT) enzyme or of the mRNA encoding this protein, obtained ex vivo from a biological sample isolated from a subject, as an efficient tool for obtaining data that can be used in the clinical diagnosis of prostate cancer.Type: ApplicationFiled: November 28, 2016Publication date: May 21, 2020Inventors: Justo P. CASTAÑO FUENTES, Raúl M. LUQUE HUERTAS, Manuel D. GAHETE ORTIZ, Daniel HORMAECHEA AGULLA, María José REQUENA TAPIA, Enrique GÓMEZ GÓMEZ, Julia CARRASCO VALIENTE, Alejandro IBÁÑEZ COSTA, María del Mar MORENO, José VALERO ROSA
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Publication number: 20190331684Abstract: The present invention relates to a diagnostic and/or prognostic method for the diagnosis and/or prognosis of cancer in a patient. Particularly, the present invention relates to diagnostic and/or prognostic methods for the diagnosis and/or prognosis of cancer which comprise quantifying the expression levels of In1-ghrelin in a plasma sample isolated from an individual; comparing the obtained levels with the expression levels of In1-ghrelin in a reference sample; and assigning the patients having expression levels of In1-ghrelin that are greater than and statistically significant with respect to the levels of the reference sample to the group of individuals at risk of having cancer. The present invention also provides a diagnostic method for the diagnosis of bladder and/or colon cancer which comprises quantifying the expression levels of In1-ghrelin, GOAT and/or GHS-R1b in tissue samples. The present invention also relates to an siRNA useful in a cancer treatment method.Type: ApplicationFiled: December 4, 2017Publication date: October 31, 2019Inventors: Raúl M. Luque Huertas, Justo P. Castaño Fuentes, Manuel D. Gahete Ortiz, Alejandro Ibañez Costa, Daniel Hormaechea Agulla, Juan Manuel Jimeñez Vacas, André Moráis Sarmento Borges Cabral, Fernando López López, Maria José Requena Tapia, Enrique Gómez Gómez, Julia Carrasco Valiente
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Patent number: 8839708Abstract: An armed vehicle (10) with improved structure includes a hull (11), which, in use, is suited to house one or more men, devices for the movement on the ground, and an armed turret (30), which is positioned on top of an upper part of the hull (11). The armed vehicle (10) includes an interface structural element (11s), which is cold-added; the interface structural element (11s) constitutes an interface element between the hull (11) and the armed turret (30).Type: GrantFiled: December 16, 2011Date of Patent: September 23, 2014Assignee: OTO Melara S.p.A.Inventors: Andrea Sandro Chiappini, Manuel D'Eusebio
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Patent number: 8716602Abstract: Cable grommets for use with raised-floor tiles permit the passage of cables while simultaneously limiting the amount of cool air escaping from under-floor ducts and plenums. The cable grommet includes a floor tile mounting flange, one or more pairs of opposed, overlapping finger assemblies, and one or more pairs of opposed finger mounting flanges for coupling the finger assemblies to the underside of the floor tile mounting flange. The edges of the of the triangularly-shaped fingers are configured to flex around the cables while the interior core section remains generally rigid and parallel to the plane of the floor to restrict the loss of cooling air. Alternatively, the cable grommet includes a floor tile mounting flange and a finger panel defining a sinusoidal cut along its length and a plurality of intersecting short cuts.Type: GrantFiled: November 1, 2011Date of Patent: May 6, 2014Assignee: Eaton CorporationInventors: Carl Cottuli, Manuel D. Linhares, Jr.
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Patent number: 8701542Abstract: An artillery ammunition loading system (100), configured to load ammunitions includes at least one projectile in a cannon or a howitzer (11). The ammunition loading system includes a first mobile loader (102a) for loading projectiles and a second mobile loader (102b) for loading propelling charges, which alternatively and at least partially automatically feed the cannon or howitzer (11) for each firing cycle.Type: GrantFiled: November 9, 2011Date of Patent: April 22, 2014Assignee: OTO Melara S.p.A.Inventors: Andrea Chiappini, Manuel D'Eusebio
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Patent number: 8679594Abstract: The invention includes the structure of a multilayer protective coating, which may have, among other properties, scratch resistance, UV absorption, and an effective refractive index matched to a polymer substrate such as polycarbonate. Each layer may contain multiple components consisting of organic and inorganic materials. The multilayer protective coating includes interleaved organic layers and inorganic layers. The organic layers may have 20% or more organic compounds such as SiOxCyHz. The inorganic layers may have 80% or more inorganic materials, such as SiO2, SiOxNy, and ZnO, or mixtures thereof. Each layer of the multilayer protective coating is a micro layer and may have a thickness of 5 angstroms or less in various embodiments. The multilayer protective coating may contain in the order of hundreds or thousands of micro layers, depending upon the design requirement of applications. In each micro layer, the components may have substantially continuous variations in concentration.Type: GrantFiled: February 24, 2011Date of Patent: March 25, 2014Assignee: Applied Materials, Inc.Inventors: Michael W. Stowell, Manuel D. Campo
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Patent number: 8627611Abstract: An aisle enclosure system including ceiling bracket assemblies, ceiling panels, vertical blanking panels, aisle duct adaptors, and accessory rails, for use with equipment racks and ceiling structures in hot-aisle and cold-aisle data centers. The ceiling assemblies may be mounted to the tops of the racks or may be suspended from an area above the racks. The aisle enclosure system further includes a moveable structure that is configured and adapted to position a ceiling panel in an closed position when the moveable structure is in a first position, and position the ceiling panel in an open position when the moveable structure is in a second position, where the moveable structure is configured and adapted to move from the first position to a second position in response to an alarm condition.Type: GrantFiled: May 6, 2011Date of Patent: January 14, 2014Inventors: Carl Cottuli, Manuel D. Linhares, Jr.
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Patent number: 8459756Abstract: Adjustable blanking panels for use with equipment racks and enclosures to cover or fill in vacant sections of the rack or enclosure, to prevent the circular flow and reentry of high temperature air into the intake of electrical and computer equipment. The adjustable blanking panels include a generally rectangular base frame that defines opposing left and right side channels, and a generally rectangular shield that is adapted to be inserted into the side channels and slide relative to the base frame, to adjust the height of the panel to the size of the vacant section. The adjustable blanking panel may further include a lip that may be used to raise or lower the shield.Type: GrantFiled: January 13, 2011Date of Patent: June 11, 2013Assignee: Eaton CorporationInventors: Manuel D. Linhares, Jr., Carl Cotulli
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Patent number: 8355246Abstract: The invention provides modular air management devices for directing or diverting air flow within an equipment cabinet or enclosure to provide adequate cooling for non-“front to back” breathing electronic devices, and include a scoop assembly, a tray assembly, a vertical mount assembly, and a shroud assembly. The air management devices are designed to direct air flow to and from “side to side” breathing and “side inlet, rear exhaust” electronic equipment. The assemblies may be mounted inside or outside enclosure rails and may be augmented with fan assemblies.Type: GrantFiled: September 18, 2009Date of Patent: January 15, 2013Inventors: Manuel D. Linhares, Jr., Michael J. Tresh, David Lucia, Dan Murphy, Meagan Foley, Mark Dignum, Richard Latino
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Publication number: 20120279779Abstract: Cable grommets for use with raised-floor tiles permit the passage of cables while simultaneously limiting the amount of cool air escaping from under-floor ducts and plenums. The cable grommet includes a floor tile mounting flange, one or more pairs of opposed, overlapping finger assemblies, and one or more pairs of opposed finger mounting flanges for coupling the finger assemblies to the underside of the floor tile mounting flange. The edges of the of the triangularly-shaped fingers are configured to flex around the cables while the interior core section remains generally rigid and parallel to the plane of the floor to restrict the loss of cooling air. Alternatively, the cable grommet includes a floor tile mounting flange and a finger panel defining a sinusoidal cut along its length and a plurality of intersecting short cuts.Type: ApplicationFiled: November 1, 2011Publication date: November 8, 2012Applicant: Eaton CorporationInventors: Carl Cottuli, Manuel D. Linhares, JR.
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Publication number: 20120180641Abstract: An armed vehicle (10) with improved structure includes a hull (11), which, in use, is suited to house one or more men, devices for the movement on the ground, and an armed turret (30), which is positioned on top of an upper part of the hull (11). The armed vehicle (10) includes an interface structural element (11s), which is cold-added; the interface structural element (11s) constitutes an interface element between the hull (11) and the armed turret (30).Type: ApplicationFiled: December 16, 2011Publication date: July 19, 2012Applicant: OTO MELARA S.p.A.Inventors: Sandro Chiappini Andrea, Manuel D'eusebio
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Publication number: 20120111182Abstract: An artillery ammunition loading system (100), configured to load ammunitions includes at least one projectile in a cannon or a howitzer (11). The ammunition loading system includes a first mobile loader (102a) for loading projectiles and a second mobile loader (102b) for loading propelling charges, which alternatively and at least partially automatically feed the cannon or howitzer (11) for each firing cycle.Type: ApplicationFiled: November 9, 2011Publication date: May 10, 2012Applicant: OTO MELARA S.p.A.Inventors: Andrea Chiappini, Manuel D'Eusebio
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Publication number: 20120049706Abstract: A frame for use with cabinets and enclosures that house electronic equipment to prevent warm air from entering into, and cool air from exiting out of, the cabinet through gaps between the structural members of the cabinet. The frame is a singular piece of material that replaces, and provides the functions of, both vertical and horizontal structural members, and may also include EIA-standard mounting holes. The top and bottom of the frame's interior may be concave to direct cooling air into, or heated air out of, the cabinet. Alternatively, a pair of angled vertical rails may be mounted to the vertical structural members of the cabinet to block the air gaps.Type: ApplicationFiled: August 31, 2011Publication date: March 1, 2012Applicant: Eaton CorporationInventors: Carl Cottuli, Manuel D. Linhares, JR.
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Publication number: 20120045631Abstract: The invention includes the structure of a multilayer protective coating, which may have, among other properties, scratch resistance, UV absorption, and an effective refractive index matched to a polymer substrate such as polycarbonate. Each layer may contain multiple components consisting of organic and inorganic materials. The multilayer protective coating includes interleaved organic layers and inorganic layers. The organic layers may have 20% or more organic compounds such as SiOxCyHz. The inorganic layers may have 80% or more inorganic materials, such as SiO2, SiOxNy, and ZnO, or mixtures thereof. Each layer of the multilayer protective coating is a micro layer and may have a thickness of 5 angstroms or less in various embodiments. The multilayer protective coating may contain in the order of hundreds or thousands of micro layers, depending upon the design requirement of applications. In each micro layer, the components may have substantially continuous variations in concentration.Type: ApplicationFiled: February 24, 2011Publication date: February 23, 2012Applicant: Applied Materials, Inc.Inventors: Michael W. Stowell, Manuel D. Campo
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Publication number: 20110271610Abstract: An aisle enclosure system including ceiling bracket assemblies, ceiling panels, vertical blanking panels, aisle duct adaptors, and accessory rails, for use with equipment racks and ceiling structures in hot-aisle and cold-aisle data centers. The ceiling assemblies may be mounted to the tops of the racks or may be suspended from an area above the racks. The aisle enclosure system further includes a moveable structure that is configured and adapted to position a ceiling panel in an closed position when the moveable structure is in a first position, and position the ceiling panel in an open position when the moveable structure is in a second position, where the moveable structure is configured and adapted to move from the first position to a second position in response to an alarm condition.Type: ApplicationFiled: May 6, 2011Publication date: November 10, 2011Applicant: Eaton CorporationInventors: Carl Cottuli, Manuel D. Linhares, JR.