Patents by Inventor Manuel E. Patarroyo

Manuel E. Patarroyo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic peptide having an ionophoric and antimicrobial activity
    Patent number: 7041647
    Abstract: This invention provides a novel synthetic peptide (P1) of 26 amino acids, which inhibits the microbial growing. Peptide P1 also shows ionophoric activity in rat liver mitochondria. Furthermore, this invention provides pharmaceutical compositions and compositions for agricultural use, which contain the peptide of the invention.
    Type: Grant
    Filed: January 7, 2004
    Date of Patent: May 9, 2006
    Assignees: Corporacion Para Investigaciones Biologicas, Universidad de Antiqquia, Fundacion Instituto de Inmunologia de Columbia, Universidad Nacional de Colombia
    Inventors: Viktor Lemeshko, Fanny Guzman, Manuel E. Patarroyo, Cesar Segura, Sergio Orduz
  • Nucleotide and amino acid sequences of protein MTP40 of M. tuberculosis and synthetic peptides derived therefrom
    Patent number: 5254459
    Abstract: The present invention relates to novel chemically synthesized nucleotides and novel chemically synthesized peptides which have been found to be effective in assaying for the presence of M. tuberculosis.
    Type: Grant
    Filed: September 4, 1992
    Date of Patent: October 19, 1993
    Inventor: Manuel E. Patarroyo
  • Nucleotide and amino acid sequences of protein MTP40 of M. tuberculosis and synthetic peptides derived therefrom
    Patent number: 5171839
    Abstract: The present invention relates to novel chemically synthesized nucleotides and novel chemically synthesized peptides which have been found to be effective in assaying for the presence of M. tuberculosis.
    Type: Grant
    Filed: August 23, 1990
    Date of Patent: December 15, 1992
    Inventor: Manuel E. Patarroyo
  • Nucleotide sequences of protein MTP40 of M. tuberculosis
    Patent number: 5169940
    Abstract: The present invention relates to novel chemically synthesized nucleotides which have been found to be effective in assaying for the presence of M. tuberculosis.
    Type: Grant
    Filed: February 11, 1992
    Date of Patent: December 8, 1992
    Inventor: Manuel E. Patarroyo
  • Protein copolymer malaria vaccine
    Patent number: 4957738
    Abstract: A mixture of the synthetic peptide compounds of the formulas:Formula (I) Tyr-Gly-Gly-Pro-Ala-Asn-Lys-Lys-Asn-Ala-Gly-OH,Formula (II) Asp-Glu-Leu-Glu-Ala-Glu-Thr-Gln-Asn-Val-Tyr-Ala-Ala-NH.sub.2, andFormula (III) Tyr-Ser-Leu-Phe-Gln-Lys-Glu-Lys-Met-Val-Leu-NH.sub.2,and compositions thereof, induces antibodies against the late stages of Plasmodium faciparum malaria and provides protection against infection with this parasite, thus providing a synthetic malaria vaccine for Plasmodium falciparum induced malaria.A synthetic protein copolymer vaccine, polymerized from a monomer which is a hybrid of formulas (II), (III) and (I), and which also includes the (Asn-Ala-Asn-Pro) sequence of the CS protein between formulas (II) and (III) and Formulas (III) and (I) of the monomer, has been shown to provide safe and complete self-limiting protection in human volunteers against the asexual blood stages of P. faciparum induced malaria.
    Type: Grant
    Filed: December 29, 1987
    Date of Patent: September 18, 1990
    Inventor: Manuel E. Patarroyo
  • Malaria vaccine
    Patent number: 4735799
    Abstract: A mixture of the synthetic peptide compounds of the formulas:Try-Gly-Gly-Pro-Ala-Asn-Lys-Lys-Asn-Ala-Gly-OH, Formula (I)Asp-Glu-Leu-Glu-Ala-Glu-Thr-Gln-Asn-Val-Tyr-Ala-Ala-NH.sub.2, Formula (II)andTyr-Ser-Leu-Phe-Gln-Lys-Glu-Lys-Met-Val-Leu-NH.sub.2, Formula (III)and compositions thereof, induces antibodies against the late stages of Plasmodium falciparum malaria and provides protection against infection with this parasite, thus providing a synthetic malaria vaccine for Plasmodium falciparum induced malaria.
    Type: Grant
    Filed: January 14, 1987
    Date of Patent: April 5, 1988
    Inventor: Manuel E. Patarroyo