Abstract: The present disclosure relates to an ionic liquid (IL)-based formulation comprising inhibitors of NADPH oxidases enzymes (Nox's), preferably isoforms 1 and 4, in particular the specific inhibitor 3-cyclohexyl-5-(2,4-dihydroxybenzylidene)-1-methyl-2-thiohydantoin, for the treatment, therapy or prevention of neurological diseases, in particular Parkinson's diseases.

Abstract: In an example, a method may include obtaining a first measurement of a first object generated using additive manufacturing apparatus based on object model data and obtaining a second measurement of a second object generated using the additive manufacturing apparatus based on object model data to which a first geometrical compensation parameter has been applied. An effect of the first geometrical compensation parameter may be determined based on the first and second measurements and, based on the determined effect, the first geometrical compensation parameter may be evaluated.

Abstract: In an example, a method includes receiving, at least one processor, object model data representing at least a portion of a first object that is to be generated by an additive manufacturing apparatus by fusing build material within a fabrication chamber. An indication of an amount of fused build material in a region of the fabrication chamber which is to be below the region in which the first object is to be generated may be determined and a dimensional compensation value to apply to the object model data representing the first object may be determined based on the determined indication. The determined dimensional compensation value may be applied to the object model data to derive modified object model data.

Abstract: In an example, a method includes receiving, by at least one processor, object model data representing at least a portion of a first object that is to be generated by an additive manufacturing apparatus. An indication of a proportion of the first object which is solid may be determined, and, based thereon, a dimensional compensation value may be determined. The determined dimensional compensation value may be applied to the object model data to determine modified object model data.

Abstract: In an example, a method includes obtaining an indication of a deviation from an expected dimension of at least one dimension of an object generated using an additive manufacturing apparatus. A geometrical compensation model to apply to object model data for generating objects using additive manufacturing to compensate for anticipated deviations in dimensions may be determined from the obtained indication. The geometrical compensation model may comprise a first value to apply to object model data to modify a specification of an external dimension; and a second, different, value to apply to object model data to modify a specification of an internal dimension.

Abstract: In an example, a method includes receiving, at least one processor, object model data representing at least a portion of an object that is to be generated by an additive manufacturing apparatus by fusing build material within a fabrication chamber, wherein the object model data comprises a mesh model comprising data describing a surface of the object. A geometrical compensation vector may be determined for the object model data, the geometrical compensation vector having a first component applying to a first axis of the fabrication chamber and a second component applying to a second axis of the fabrication chamber. A geometrical compensation to apply to at least one location on the surface of the object may be determined by determining a product of the geometrical compensation vector and a vector indicative of the normal of the object surface at the location and the determined geometrical compensation may be applied to the object model data to generate modified object model data.

Abstract: In an example a tangible machine-readable medium stores instructions which, when executed by a processor, cause the processor to determine an object generation arrangement for additive manufacturing based on a separation distance between objects, wherein the separation distance varies based on an intended location of object generation.

Abstract: Examples include a method implemented in a three dimensional printing system wherein a print job comprising a plurality of parts to be printed is received. A part feature intended to be printed in a specific print mode is identified, wherein the specific print mode is customized for the part feature. The print job is executed using the specific print mode for the part feature. The use of the specific print mode is monitored.

Abstract: In an example, a machine-readable medium stores instructions which, when executed by a processor may cause the processor to modify data for characterising geometrical modifications for use by each of a plurality of additive manufacturing apparatus, wherein a modification for a particular additive manufacturing apparatus is based on dimensions of objects generated by that apparatus.

Abstract: In an example, a tangible machine-readable medium stores instructions which, when executed by a processor, cause the processor to evaluate a plurality of possible object generation arrangements based on a default separation distance and an enhanced separation distance, wherein the enhanced separation distance is used to assess predefined object sub-portions.

Abstract: A method of processing merged 3D geometric information in a 3D printing system is described that receives a 3D object model file representing at least two physical 3D parts to be printed, wherein the 3D object model file comprises 3D geometric information for the at least two physical 3D parts, wherein the 3D geometric information is encoded as at least one logical 3D part, wherein at least one of the at least one logical 3D part comprises merged 3D geometric information for at least a subset of the at least two physical 3D parts. From the 3D object model file, a separate set of 3D geometric information for each of the at least two physical 3D parts is extracted and each separate set of 3D geometric information is processed individually before printing the physical 3D parts.

Abstract: In some examples, a system receives measurement data from measurements of first three-dimensional (3D) parts formed on a build bed of an additive manufacturing machine with different contone levels of a liquid agent, and determines, based on the measurement data, geometrical deviations of the first 3D parts from a baseline geometrical property. The system generates, based on the determined geometrical deviations, a model that correlates contone levels of the liquid agent to corresponding geometrical deviations, the model for use in an adjustment of the liquid agent based on a contone level adjustment to compensate for a geometrical deviation when building second 3D parts with the additive manufacturing machine or another additive manufacturing machine.

Abstract: In an example, object model data representing at least a portion of an object defining an initial object geometry is received, wherein the object is to be generated by an additive manufacturing apparatus by fusing build material using a radiant heater. Based on a non-uniform radiant heating distribution of the additive manufacturing apparatus, a modified object geometry may be determined, wherein a local modification of the object geometry is determined based on a local radiant heating parameter determined from the non-uniform radiant heating distribution.

Abstract: A self-retrievable anchor with a shovel, lever, and manifold contains no welded parts eliminating weld failure due to tensional and bending forces during anchor retrieval. The anchor has interchangeable parts. The manifold attaches the shovel to lever, and contains at least an internal breakable fuse. A specific dimensioned fuse to anchor size is used. The fuse is not universal. When a tensional force is applied above fuse shear strength capacity, and below breaking strength of the rope, the fuse breaks rotating the shovel 180° about a pivot hinge pin. The anchor is released when stuck at sea bottom without any loss. The anchor's interchangeable parts makes it capable to change shovel shapes suitable to different sea bottom conditions. A stop bar on the shovel portion may be included. The lever may also detach during retrieval by a breakable pivot hinge pin or fuse pin alone, and shovel/manifold later replaced.

Abstract: A system includes a controller to receive data corresponding to an object or slices of the object to be generated by a 3D printer, wherein the 3D printer includes an array of printhead nozzles to selectively eject a print agent on a layer of build material in a build chamber having a build chamber wall, the array of printhead nozzles spanning substantially the full width of the build chamber and moveable along a length of the build chamber. The controller to generate first print data used to generate layers of the object based on the received object data, and to generate second print data used to generate layers of a sacrificial barrier located between the object and the build chamber wall, the second print data is generated such that different parts of the sacrificial barrier are generated using a different plurality of nozzles of the array of printhead nozzles.

Abstract: In an example, mesh model data representing at least a portion of a print job to be generated by an additive manufacturing apparatus by solidifying build material is received at a processor. Using a processor and based on the mesh model data, it is validated whether the three-dimensional print job described by the mesh model data conforms with at least one of material-dependent shape constraints and apparatus-dependent shape constraints of the additive manufacturing apparatus. If the result of the validation is positive, the mesh model data is rendered, using a processor for manufacturing the three-dimensional print job by an additive manufacturing apparatus. If the result of the validation is negative, a predetermined action is performed.

Abstract: In an example, a method includes receiving, at at least one processor, object model data representing at least a portion of an object that is to be generated by an additive manufacturing apparatus by fusing build material within a fabrication chamber. At least one of a plurality of different geometrical compensation models to be applied to the object model data may be selected wherein the geometrical compensation models are to determine geometrical compensations to compensate for object deformation in additive manufacturing. An object generation operation based on a modification of the object model data using the or each selected geometrical compensation mode may be simulated and predicted attributes of the object when generated based on the or each simulation may be displayed. FIG.

Abstract: A method is described in which model data describing a three-dimensional object is received. A first offset is applied to a surface of the object, the first offset being applied to the model data. The model data is converted to voxel data, and a second offset is applied to the surface of the object, the second offset being applied to the voxel data.

Abstract: In an example, a method includes receiving object model data representing at least a portion of an object that is to be generated by an additive manufacturing apparatus by fusing build material within a fabrication chamber. At least one of a number of different geometrical compensation models to be applied to the object model data may be selected, where the geometrical compensation models are to determine geometrical compensations to compensate for object deformation in additive manufacturing. An object generation operation based on a modification of the object model data using the or each selected geometrical compensation mode may be simulated and predicted attributes of the object when generated based on the or each simulation may be displayed.

Abstract: A method of configuring an additive manufacturing system. The method comprises configuring the additive manufacturing system with a first value of an operation parameter associated with the additive manufacturing system and, with the additive manufacturing system configured with the first value of the operation parameter, forming, in a build chamber, a first object The additive manufacturing system is subsequently configured with a second value of the operation parameter and, with the additive manufacturing system configured with the second value of the operation parameter, a second object is formed in the build chamber, subsequently to forming the first object. The method further includes receiving a signal indicative of which of the first value or the second value the operation parameter is to be configured with for subsequent operation of the additive manufacturing system.