Patents by Inventor Manuel Guzman
Manuel Guzman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150313867Abstract: The invention relates to the use of a combination of cannabinoids, particularly tetrahydrocannabinol (THC) and cannabidiol (CBD), in the manufacture of a medicament for use in the treatment of cancer. In particular the cancer to be treated is a brain tumour, more particularly a glioma, more particularly still a glioblastoma multiforme (GBM).Type: ApplicationFiled: January 14, 2015Publication date: November 5, 2015Inventors: Guillermo Velasco Diez, Manuel Guzman Pastor, Mar Lorente, Sofia Torres, Fatima Rodriguez
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Publication number: 20150086653Abstract: This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be treated is cancer of the prostate, cancer of the breast or cancer of the colon.Type: ApplicationFiled: April 24, 2014Publication date: March 26, 2015Applicants: GW Pharma Limited, Otsuka Pharmaceutical Co., LimitedInventors: Daniela Parolaro, Paola Massi, Angelo Antonio Izzo, Francesca Borelli, Gabriella Aviello, Vincenzo Di Marzo, Luciano De Petrocellis, Aniello Schiano Moriello, Alessia Ligresti, Ruth Alexandra Ross, Lesley Ann Ford, Sharon Anavi-Goffer, Manuel Guzman, Guillermo Velasco, Mar Lorente, Sofia Torres, Tetsuro Kikuchi, Geoffrey Guy, Colin Stott, Stephen Wright, Alan Sutton, David Potter, Etienne De Meijer
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Publication number: 20150050065Abstract: An applicator assembly includes a head portion having a proximal, a distal end, and an interior portion defining a fluid chamber, a container slidably coupled to the body, a sealing member sealing an end of the container, and a lifting member, wherein the lifting member is mounted in the interior portion of the head portion and an interior of the container is placed in fluid communication with the application member by way of a fluid conduit that is formed around the sealing member from the container to the fluid chamber when the container is axially translated toward the head portion and the lifting member lifts the sealing member.Type: ApplicationFiled: October 31, 2014Publication date: February 19, 2015Inventor: Manuel GUZMAN
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Patent number: 8899859Abstract: An applicator assembly includes a head portion having a proximal, a distal end, and an interior portion defining a fluid chamber, a container slidably coupled to the body, a sealing member sealing an end of the container, and a lifting member, wherein the lifting member is mounted in the interior portion of the head portion and an interior of the container is placed in fluid communication with the application member by way of a fluid conduit that is formed around the sealing member from the container to the fluid chamber when the container is axially translated toward the head portion and the lifting member lifts the sealing member.Type: GrantFiled: December 16, 2011Date of Patent: December 2, 2014Assignee: Carefusion 2200, Inc.Inventor: Manuel Guzman
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Publication number: 20140314757Abstract: The present invention relates to phytocannabinoids for use in the treatment of a breast cancer. In a first embodiment the invention relates to an oral presentation of tetrahydrocannabinol (THC) for use in the treatment of aggressive breast cancer, characterised by overexpression of the Her2 gene. In a second embodiment the invention relates to the phytocannabinoid cannabidiol (CBD) for use in the treatment of aggressive breast cancer, characterised by overexpression of the Her2 gene. In a third embodiment the invention relates to the combination of the phytocannabinoids tetrahydrocannabinol (THC) and cannabidiol (CBD) for use in the treatment of breast cancer or to treat, prevent or to reduce the risk of a cancer metastasising.Type: ApplicationFiled: October 17, 2012Publication date: October 23, 2014Inventors: Cristina Sanchez, Manuel Guzman, Stephen Wright, Colin Stott, Maria Munoz Caffarel, Clara Andradas, Eduardo Perz Gomez
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Patent number: 8864399Abstract: An applicator assembly includes a body defining a pocket, a closed ampoule received in the pocket, an integrated protective device attached to the body and enclosing the pocket, a lever projecting from the body, at least one tappet that bears against an external surface of the pocket and fractures the ampoule when the lever is pivoted, and an application member secured to the body, wherein an interior of the pocket is placed in fluid communication with the application member by way of through-holes provided in the integrated protective device. A method for manufacturing the applicator assembly includes rotating the protective device from an open position into a closed position to enclose the ampoule in the pocket before the application member is attached to the body so that the fluid to be dispensed will flow through the protective device and contact the application member when the ampoule is fractured.Type: GrantFiled: June 30, 2010Date of Patent: October 21, 2014Assignee: Carefusion 2200, Inc.Inventors: Manuel Guzman, James P. McDonald
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Publication number: 20140287067Abstract: The invention relates to the use of a combination of cannabinoids, particularly tetrahydrocannabinol (THC) and cannabidiol (CBD), in the manufacture of a medicament for use in the treatment of cancer. In particular the cancer to be treated is a brain tumour, more particularly a glioma, more particularly still a glioblastoma multiforme (GBM).Type: ApplicationFiled: November 14, 2013Publication date: September 25, 2014Applicants: GW Pharma Limited, Otsuka Pharmaceutical Co., LimitedInventors: Guillermo Velasco Diez, Manuel Guzman Pastor, Mar Lorente, Sofia Torres, Fatima Rodriguez
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Patent number: 8801312Abstract: An applicator assembly includes a head portion having a proximal, a distal end, and an interior portion defining a fluid chamber, a container slidably coupled to the body, a breakable membrane sealing an end of the container, and a hollow puncture mechanism, wherein the hollow puncture mechanism is mounted in the interior portion of the head portion and an interior of the container is placed in fluid communication with the application member by way of a fluid conduit that is formed through the hollow puncture mechanism from the container to the fluid chamber when the container is axially translated toward the head portion and the puncture mechanism pierces the breakable membrane.Type: GrantFiled: December 16, 2011Date of Patent: August 12, 2014Assignee: Carefusion 2200, Inc.Inventors: Manuel Guzman, Kyle W. Boone, Miguel Rivera
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Patent number: 8790719Abstract: This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be treated is cancer of the prostate, cancer of the breast or cancer of the colon.Type: GrantFiled: March 11, 2011Date of Patent: July 29, 2014Assignees: GW Pharma Limited, Otsuka Pharmaceutical Co., LimitedInventors: Daniela Parolaro, Paola Massi, Angelo Antonio Izzo, Francesca Borelli, Gabriella Aviello, Vincenzo Di Marzo, Luciano De Petrocellis, Aniello Schiano Moriello, Alessia Ligresti, Ruth Alexandra Ross, Lesley Ann Ford, Sharon Anavi-Goffer, Manuel Guzman, Guillermo Velasco, Mar Lorente, Sofia Torres, Tetsuro Kikuchi, Geoffrey Guy, Colin Stott, Stephen Wright, Alan Sutton, David Potter, Etienne De Meijer
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Publication number: 20140186092Abstract: An applicator assembly includes a body having a proximal and a distal end, a container slidably coupled to the body, a valve cap coupled to the container, and an application member attached to the distal end, wherein an interior of the container is placed in fluid communication with the application member by way of a fluid conduit that is only accessible when one of the body and the container are axially translated in an opposite direction away from each other.Type: ApplicationFiled: March 7, 2014Publication date: July 3, 2014Applicant: CAREFUSION 2200, INC.Inventors: James Patrick MCDONALD, MANUEL GUZMAN
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Patent number: 8708983Abstract: An applicator assembly includes a body having a proximal and a distal end, a container slidably coupled to the body, a valve cap coupled to the container, and an application member attached to the distal end, wherein an interior of the container is placed in fluid communication with the application member by way of a fluid conduit that is only accessible when one of the body and the container are axially translated in an opposite direction away from each other.Type: GrantFiled: June 29, 2010Date of Patent: April 29, 2014Assignee: Carefusion 2200, Inc.Inventors: James Patrick McDonald, Manuel Guzman
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Patent number: 8632825Abstract: The invention relates to the use of a combination of cannabinoids, particularly tetrahydrocannabinol (THC) and cannabidiol (CBD), in the manufacture of a medicament for use in the treatment of cancer. In particular the cancer to be treated is a brain tumor, more particularly a glioma, more particularly still a glioblastoma multiforme (GBM).Type: GrantFiled: June 4, 2009Date of Patent: January 21, 2014Assignees: GW Pharma Limited, Otsuka Pharmaceutical Co., LimitedInventors: Guillermo Velasco Diez, Manuel Guzman Pastor, Mar Lorente, Sofia Torres, Fatima Rodriguez
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Publication number: 20130287471Abstract: An applicator assembly includes a container having a proximal end, a distal end, and an interior portion defining a chamber, an application member attached to the distal end of the container, and a tearable solution reservoir disposed within the chamber, the tearable solution reservoir comprising a tearing member, wherein actuating the tearing member to tear the tearable solution reservoir brings the container, the tearable solution reservoir, and the application member into fluid communication with each other.Type: ApplicationFiled: April 27, 2012Publication date: October 31, 2013Inventors: Kyle W. BOONE, Manuel Guzman
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Publication number: 20130251439Abstract: An applicator assembly includes a head portion having a proximal end, a distal end, and an interior portion defining a fluid chamber, a container slidably coupled to the head portion, a plug sealing an end of the container, an application member attached to the distal end, and one or more orifices formed through a surface of the plug, wherein the plug is mounted in the interior portion of the head portion and an interior of the container is placed in fluid communication with the application member by way of a fluid conduit that is formed through the plug from the container to the fluid chamber when the container is axially translated toward the head portion to bring the one or more orifices into fluid communication with the containerType: ApplicationFiled: March 22, 2012Publication date: September 26, 2013Applicant: CAREFUSION 2200, INC.Inventor: Manuel GUZMAN
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Publication number: 20130156485Abstract: An applicator assembly includes a head portion having a proximal, a distal end, and an interior portion defining a fluid chamber, a container slidably coupled to the body, a sealing member sealing an end of the container, and a lifting member, wherein the lifting member is mounted in the interior portion of the head portion and an interior of the container is placed in fluid communication with the application member by way of a fluid conduit that is formed around the sealing member from the container to the fluid chamber when the container is axially translated toward the head portion and the lifting member lifts the sealing member.Type: ApplicationFiled: December 16, 2011Publication date: June 20, 2013Applicant: CAREFUSION 2200, INCInventor: Manuel GUZMAN
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Publication number: 20130156486Abstract: An applicator assembly includes a head portion having a proximal, a distal end, and an interior portion defining a fluid chamber, a container slidably coupled to the body, a breakable membrane sealing an end of the container, and a hollow puncture mechanism, wherein the hollow puncture mechanism is mounted in the interior portion of the head portion and an interior of the container is placed in fluid communication with the application member by way of a fluid conduit that is formed through the hollow puncture mechanism from the container to the fluid chamber when the container is axially translated toward the head portion and the puncture mechanism pierces the breakable membrane.Type: ApplicationFiled: December 16, 2011Publication date: June 20, 2013Applicant: CAREFUSION 2200, INCInventors: Manuel GUZMAN, Kyle W. Boone, Miguel Rivera
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Publication number: 20130059018Abstract: This invention relates to the use of phytocannabinoids, either in an isolated form or in the form of a botanical drug substance (BDS) in the treatment of cancer. Preferably the cancer to be treated is cancer of the prostate, cancer of the breast or cancer of the colon.Type: ApplicationFiled: March 11, 2011Publication date: March 7, 2013Applicants: OTSUKA PHARMACEUTICAL CO., LIMITED, GW PHARMA LIMITEDInventors: Daniela Parolaro, Paola Massi, Angelo Antonio Izzo, Francesca Borelli, Gabriella Aviello, Vincenzo Di Marzo, Luciano De Petrocellis, Aniello Schiano Moriello, Alessia Ligresti, Ruth Alexandra Ross, Lesley Ann Ford, Sharon Anavi-Goffer, Manuel Guzman, Guillermo Velasco, Mar Lorente, Sofia Torres, Tetsuro Kikuchi, Geoffrey Guy, Colin Stott, Stephen Wright, Alan Sutton, David Potter, Etienne De Meijer
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Publication number: 20120003029Abstract: An applicator assembly includes a body defining a pocket, a closed ampoule received in the pocket, an integrated protective device attached to the body and enclosing the pocket, a lever projecting from the body, at least one tappet that bears against an external surface of the pocket and fractures the ampoule when the lever is pivoted, and an application member secured to the body, wherein an interior of the pocket is placed in fluid communication with the application member by way of through-holes provided in the integrated protective device. A method for manufacturing the applicator assembly includes rotating the protective device from an open position into a closed position to enclose the ampoule in the pocket before the application member is attached to the body so that the fluid to be dispensed will flow through the protective device and contact the application member when the ampoule is fractured.Type: ApplicationFiled: June 30, 2010Publication date: January 5, 2012Applicant: CAREFUSION 2200, INC.Inventors: MANUEL GUZMAN, James P. McDonald
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Publication number: 20110319842Abstract: An applicator assembly includes a body having a proximal and a distal end, a container slidably coupled to the body, a valve cap coupled to the container, and an application member attached to the distal end, wherein an interior of the container is placed in fluid communication with the application member by way of a fluid conduit that is only accessible when one of the body and the container are axially translated in an opposite direction away from each other.Type: ApplicationFiled: June 29, 2010Publication date: December 29, 2011Applicant: CAREFUSION 2200, INC.Inventors: JAMES P. MCDONALD, MANUEL GUZMAN
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Publication number: 20110117216Abstract: The invention relates to the use of a combination of cannabinoids, particularly tetrahydrocannabinol (THC) and cannabidiol (CBD), in the manufacture of a medicament for use in the treatment of cancer. In particular the cancer to be treated is a brain tumour, more particularly a glioma, more particularly still a glioblastoma multiforme (GBM).Type: ApplicationFiled: June 4, 2009Publication date: May 19, 2011Inventors: Guillermo Velasco Diez, Manuel Guzman Pastor, Mar Lorente, Sofia Torres, Fatima Rodriguez