Patents by Inventor Manuel J. Buttini

Manuel J. Buttini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PREVENTION AND TREATMENT OF SYNUCLEINOPATHIC AND AMYLOIDOGENIC DISEASE
    Publication number: 20210032318
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Application
    Filed: April 7, 2020
    Publication date: February 4, 2021
    Applicants: Prothena Biosciences Limited, The Regents of the University of California
    Inventors: Dale B. Schenk, Eliezer Masliah, Manuel J. Buttini, Tamie J. Chilcote, Edward M. Rockenstein, Kate Dora Games
  • PREVENTION AND TREATMENT OF SYNUCLEINOPATHIC AND AMYLOIDOGENIC DISEASE
    Publication number: 20190300598
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Application
    Filed: February 21, 2019
    Publication date: October 3, 2019
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: DALE B. SCHENK, ELIEZER MASLIAH, MANUEL J. BUTTINI, TAMIE J. CHILCOTE, EDWARD M. ROCKENSTEIN, KATE DORA GAMES
  • PREVENTION AND TREATMENT OF SYNUCLEINOPATHIC AND AMYLOIDOGENIC DISEASE
    Publication number: 20170349651
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Application
    Filed: May 30, 2017
    Publication date: December 7, 2017
    Inventors: Dale B. Schenk, Eliezer Masliah, Manuel J. Buttini, Tamie J. Chilcote, Edward M. Rockenstein, Kate Dora Games
  • Prevention and Treatment of Synucleinopathic and Amyloidogenic Disease
    Publication number: 20160184416
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Application
    Filed: August 27, 2015
    Publication date: June 30, 2016
    Inventors: Dale B. Schenk, Eliezer Masliah, Manuel J. Buttini, Chilcote J. Tamie, Edward Rockenstein, Kate Dora Games
  • PREVENTION AND TREATMENT OF SYNUCLEINOPATHIC AND AMYLOIDOGENIC DISEASE
    Publication number: 20160060331
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Application
    Filed: August 31, 2015
    Publication date: March 3, 2016
    Inventors: Dale B. Schenk, Eliezer Masliah, Manuel J. Buttini, Chilcote J. Tamie, Edward M. Rockenstein, Kate Dora Games
  • Use of tau to monitor immunotherapy
    Patent number: 9272030
    Abstract: The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered is monitored by measuring levels of tau.
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: March 1, 2016
    Assignees: JANSSEN SCIENCES IRELAND UC, WYETH LLC
    Inventors: Ronald Black, Jack Steven Jacobsen, Lioudmila Tchistiakova, Angela Widom, Davinder Gill, Lars Ekman, Ivan Lieberburg, Michael Grundman, James Callaway, Keith M. Gregg, Wagner Zago, Manuel J. Buttini, Gene G. Kinney
  • Treatment and delay of outset of synucleinopathic and amyloidogenic disease
    Patent number: 9034337
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Grant
    Filed: February 23, 2007
    Date of Patent: May 19, 2015
    Assignee: Prothena Biosciences Limited
    Inventors: Dale B. Schenk, Eliezar Masliah, Manuel J. Buttini, Tamie J. Chilcote, Edward Rockenstein, Kate Dora Games
  • USE OF TAU TO MONITOR IMMUNOTHERAPY
    Publication number: 20150118223
    Abstract: The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered is monitored by measuring levels of tau.
    Type: Application
    Filed: April 22, 2011
    Publication date: April 30, 2015
    Applicants: WYETH LLC, JANSSEN ALZHEIMER IMMUNOTHERAPY
    Inventors: Ronald Black, Jack Steven Jacobsen, Lioudmila Tchistiakova, Angela Widom, Davinder Gill, Lars Ekman, Ivan Lieberburg, Michael Grundman, James Callaway, Keith M. Gregg, Wagner Zago, Manuel J. Buttini, Gene G. Kinney
  • USE OF TAU TO MONITOR IMMUNOTHERAPY
    Publication number: 20130209453
    Abstract: The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered is monitored by measuring levels of tau.
    Type: Application
    Filed: April 22, 2011
    Publication date: August 15, 2013
    Applicants: WYETH LLC, JANSSEN ALZHEIMER IMMUNOTHERAPY
    Inventors: Ronald Black, Jack Steven Jacobsen, Lioudmila Tchistiakova, Angela Widom, Davinder Gill, Lars Ekman, Ivan Lieberburg, Michael Grundman, James Callaway, Keith M. Gregg, Wagner Zago, Manuel J. Buttini
  • PREVENTION AND TREATMENT OF SYNUCLEINOPATHIC AND AMYLOIDOGENIC DISEASE
    Publication number: 20120201842
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Application
    Filed: February 22, 2012
    Publication date: August 9, 2012
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, ELAN PHARMACEUTICALS, INC.
    Inventors: Dale B. Schenk, Eliezer Masliah, Manuel J. Buttini, Tamie J. Chilcote, Edward Rockenstein, Kate Dora Games
  • Prevention and Treatment of Synucleinopathic and Amyloidogenic Disease
    Publication number: 20120142902
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Application
    Filed: December 14, 2011
    Publication date: June 7, 2012
    Applicants: The Regents of the University of California, Elan Pharmaceuticals, Inc.
    Inventors: Dale B. Schenk, Eliezer Masliah, Manuel J. Buttini, Chilcote J. Tamie, Edward Rockenstein, Kate Dora Games
  • Prevention and treatment of synucleinopathic and amyloidogenic disease
    Patent number: 8147833
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Grant
    Filed: February 22, 2008
    Date of Patent: April 3, 2012
    Assignees: Neotope Biosciences Limited, The Regents of the University of California
    Inventors: Dale B. Schenk, Eliezer Masliah, Manuel J. Buttini, Tamie J. Chilcote, Edward Rockenstein, Kate Dora Games
  • Prevention and treatment of synucleinopathic and amyloidogenic disease
    Patent number: 8092801
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Grant
    Filed: February 25, 2008
    Date of Patent: January 10, 2012
    Assignee: Neotope Biosciences Limited
    Inventors: Dale B. Schenk, Eliezar Masliah, Manuel J. Buttini, Tamie J. Chilcote, Edward Rockenstein, Kate Dora Games
  • Treatment and delay of onset of synucleinopathic and amyloidogenic disease
    Patent number: 7919088
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: April 5, 2011
    Assignees: Elan Pharmaceuticals, Inc., The Regents of the University of California
    Inventors: Dale B. Schenk, Kate Dora Games, Manuel J. Buttini, Tamie J. Chilcote, Edward Rockenstein, Eliezar Masliah
  • Prevention and treatment of synucleinopathic and amyloidogenic disease
    Publication number: 20100278814
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Application
    Filed: February 25, 2008
    Publication date: November 4, 2010
    Applicants: ELAN PHARMACEUTICALS, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Dale B. Schenk, Eliezar Masliah, Manuel J. Buttini, Tamie J. Chilcote, Edward Rockenstein, Kate Dora Games
  • Prevention and Treatment of Synucleinopathic and Amyloidogenic Disease
    Publication number: 20100086545
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Application
    Filed: February 22, 2008
    Publication date: April 8, 2010
    Applicants: The Regents of the University of California, Elan Pharmaceuticals, Inc.
    Inventors: Dale B. Schenk, Eliezer Masliah, Manuel J. Buttini, Chilcote J. Tamie, Edward Rockenstein, Kate Dora Games
  • Prevention and treatment of synucleinopathic and amyloidogenic disease
    Publication number: 20100031377
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Application
    Filed: August 9, 2005
    Publication date: February 4, 2010
    Applicant: ELAN PHARMACEUTICALS, INC.
    Inventors: Dale B Schenk, Eliezer Masliah, Manuel J. Buttini, Tamie J. Chilcote, Edward Rockenstein, Kate Dora Games
  • Prevention and treatment of synucleinopathic and amyloidogenic disease
    Publication number: 20090208487
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Application
    Filed: February 23, 2007
    Publication date: August 20, 2009
    Applicant: Elan Pharmaceuticals, Inc.
    Inventors: Dale B. Schenk, Kate Dora Games, Manuel J. Buttini, Tamie J. Chilcote, Edward Rockenstein, Eliezar Masliah
  • Prevention And Treatment of Synucleinopathic And Amyloidogenic Disease
    Publication number: 20080175838
    Abstract: The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
    Type: Application
    Filed: August 20, 2007
    Publication date: July 24, 2008
    Applicants: Elan Pharmaceuticals, Inc., The Regents of the University of California
    Inventors: Dale B. Schenk, Kate Dora Games, Manuel J. Buttini, Tamie J. Chilcote, Edward Rockenstein, Eliezar Masliah