Patents by Inventor Manuel J. Jayo

Manuel J. Jayo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISOLATED RENAL CELLS AND USES THEREOF
    Publication number: 20240108657
    Abstract: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
    Type: Application
    Filed: October 10, 2023
    Publication date: April 4, 2024
    Inventors: Sharon C. Presnell, Andrew T. Bruce, Shay M. Wallace, Sumana Choudhury, Russell W. Kelley, Manuel J. Jayo, Jessica J. Reinsch, Patricia D. Tatsumi, Timothy A. Bertram, Eric S. Werdin, Oluwatoyin A. Knight, H. Scott Rapoport, Roger M. Ilagan
  • BIOACTIVE RENAL CELLS
    Publication number: 20210238600
    Abstract: The present invention concerns bioactive renal cell populations, renal cell constructs, and methods of making and using the same.
    Type: Application
    Filed: February 9, 2021
    Publication date: August 5, 2021
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric S. Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Jr., Darell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • Bioactive renal cells
    Patent number: 11066666
    Abstract: The present invention concerns bioactive renal cells populations, renal cell constructs, and methods of making and using the same.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: July 20, 2021
    Assignee: inRegen
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Darell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • ISOLATED RENAL CELLS AND USES THEREOF
    Publication number: 20190117695
    Abstract: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
    Type: Application
    Filed: October 15, 2018
    Publication date: April 25, 2019
    Inventors: Sharon C. Presnell, Andrew T. Bruce, Shay M. Wallace, Sumana Choudhury, Russell W. Kelley, Manuel J. Jayo, Jessica J. Reinsch, Patricia D. Tatsumi, Timothy Bertram, Eric S. Werdin, Oluwatoyin A. Knight, H. Scott Rapoport, Roger M. Ilagan
  • Isolated renal cells and uses thereof
    Patent number: 10105392
    Abstract: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: October 23, 2018
    Assignee: INREGEN
    Inventors: Sharon C. Presnell, Andrew Bruce, Shay M. Wallace, Sumana Choudhury, Russell W. Kelley, Manuel J. Jayo, Jessica J. Reinsch, Patricia D. Tatsumi, Timothy A. Bertram, Eric S. Werdin, Oluwatoyin A. Knight, H. Scott Rapoport, Roger M. Ilagan
  • BIOACTIVE RENAL CELLS
    Publication number: 20180282726
    Abstract: The present invention concerns bioactive renal cells populations, renal cell constructs, and methods of making and using the same.
    Type: Application
    Filed: March 19, 2018
    Publication date: October 4, 2018
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Darrell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • Bioactive renal cells
    Patent number: 10077442
    Abstract: The present invention concerns bioactive renal cell populations, renal cell constructs, and methods of making and using the same.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: September 18, 2018
    Assignee: inRegen
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Darell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • Bioactive renal cells
    Patent number: 10030242
    Abstract: The present invention concerns bioactive renal cell populations, renal cell constructs, and methods of making and using the same.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: July 24, 2018
    Assignee: InRegen
    Inventors: Timothy A. Bertram, Roger M. Ilagan, Russell W. Kelley, Sharon C. Presnell, Sumana Choudhury, Andrew T. Bruce, Christopher W. Genheimer, Bryan R. Cox, Kelly I. Guthrie, Joydeep Basu, Shay M. Wallace, Eric Werdin, Oluwatoyin A. Knight, Namrata D. Sangha, John W. Ludlow, Craig R. Halberstadt, Richard Payne, Neil F. Robins, Darell McCoy, Deepak Jain, Manuel J. Jayo, Elias A. Rivera, Thomas Spencer, Benjamin Watts
  • CELL SCAFFOLD CONSTRUCTS
    Publication number: 20180071074
    Abstract: The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
    Type: Application
    Filed: May 18, 2017
    Publication date: March 15, 2018
    Inventors: John W. Ludlow, Manuel J. Jayo, Joydeep Basu, Timothy A. Bertram, Christopher W. Genheimer, Kelly I. Guthrie, Roger M. Ilagan, Deepak Jain, Oluwatoyin A. Knight, Richard Payne, Sarah F. Quinlan, H. Scott Rapoport, Namrata D. Sangha
  • ISOLATED RENAL CELLS AND USES THEREOF
    Publication number: 20160206659
    Abstract: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
    Type: Application
    Filed: November 18, 2015
    Publication date: July 21, 2016
    Inventors: Sharon C. Presnell, Andrew Bruce, Shay M. Wallace, Sumana Choudhury, Russell W. Kelley, Manuel J. Jayo, Jessica J. Reinsch, Patricia D. Tatsumi, Timothy A. Bertram, Eric S. Werdin, Oluwatoyin A. Knight, H. Scott Rapoport, Roger M. Ilagan
  • Cell scaffold constructs
    Patent number: 9271824
    Abstract: The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: March 1, 2016
    Assignee: REGENMEDTX, LLC
    Inventors: John W. Ludlow, Manuel J. Jayo, Joydeep Basu, Timothy A. Bertram, Christopher W. Genheimer, Kelly I. Guthrie, Roger M. Ilagan, Deepak Jain, Oluwatoyin A. Knight, Richard Payne, Sarah F. Quinlan, H. Scott Rapoport, Namrata D. Sangha
  • Isolated renal cells and uses thereof
    Patent number: 9192629
    Abstract: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: November 24, 2015
    Assignee: REGENMEDTX, LLC
    Inventors: Sharon C. Presnell, Andrew Bruce, Shay M. Wallace, Sumana Choudhury, Russell W. Kelley, Manuel J. Jayo, Jessica J. Reinsch, Patricia D. Tatsumi, Timothy A. Bertram, Eric S. Werdin, Oluwatoyin A. Knight, H. Scott Rapoport, Roger M. Ilagan
  • SMOOTH MUSCLE CELL CONSTRUCTS
    Publication number: 20150030657
    Abstract: The present invention relates to the regeneration, reconstruction, augmentation or replacement of luminal organs or tissue structures in a subject in need using scaffolds seeded with autologous or non-autologous cell populations that are or are not derived from the corresponding organ or tissue structure that is the subject of the regeneration, reconstruction, augmentation or replacement.
    Type: Application
    Filed: May 3, 2011
    Publication date: January 29, 2015
    Applicant: TENGION, INC.
    Inventors: John W. Ludlow, Manuel J. Jayo, Joydeep Basu, Timothy A. Bertram, Christopher W. Genheimer, Kelly I. Guthrie, Roger M. Ilagan, Deepak Jain, Oluwatoyin A. Knight, Richard Payne, Sarah F. Quinlan, H. Scott Rapoport, Namrata D. Sangha, Jacob E. Shokes, Teresa B. Burnette, Sarah A. Boyd, Craig R. Halberstadt, Dominic M. Justewicz, Elias A. Rivera, Wendy Sharp, Neil F. Robbins
  • SCAFFOLDS FOR ORGAN RECONSTRUCTION AND AUGMENTATION
    Publication number: 20140107804
    Abstract: Biocompatible synthetic or natural scaffolds are provided for the reconstruction, repair, augmentation or replacement of organs or tissue structures in a patient in need of such treatment. The scaffolds are shaped to conform to at least a part of the organ or tissue structure and may be seeded with one or more cell populations. Inserts, receptacles and ports are also provided for the attachment of tubular vessels to the neo-organ scaffolds. The seeded scaffolds are implanted into the patient at the site in need of treatment to form an organized organ or tissue structure. The scaffolds may be used to form organs or tissues, such as bladders, urethras, valves, and blood vessels.
    Type: Application
    Filed: September 17, 2013
    Publication date: April 17, 2014
    Applicant: Tengion, Inc.
    Inventors: Timothy A. Bertram, Andrew Bruce, Deepak Jain, Manuel J. Jayo, John W. Ludlow, Darell McCoy, Richard Payne, Namrata D. Sangha, Oluwatoyin A. Knight
  • Scaffolds for organ reconstruction and augmentation
    Patent number: 8696760
    Abstract: Biocompatible synthetic or natural scaffolds are provided for the reconstruction, repair, augmentation or replacement of organs or tissue structures in a patient in need of such treatment. The scaffolds are shaped to conform to at least a part of the organ or tissue structure and may be seeded with one or more cell populations. Inserts, receptacles and ports are also provided for the attachment of tubular vessels to the neo-organ scaffolds. The seeded scaffolds are implanted into the patient at the site in need of treatment to form an organized organ or tissue structure. The scaffolds may be used to form organs or tissues, such as bladders, urethras, valves, and blood vessels.
    Type: Grant
    Filed: March 1, 2011
    Date of Patent: April 15, 2014
    Assignee: Tengion, Inc.
    Inventors: Timothy A. Bertram, Andrew Bruce, Deepak Jain, Manuel J. Jayo, John W. Ludlow, Darell McCoy, Richard Payne, Namrata D. Sangha, Oluwatoyin A. Knight
  • CELL SCAFFOLD CONSTRUCTS
    Publication number: 20130173015
    Abstract: The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
    Type: Application
    Filed: November 20, 2012
    Publication date: July 4, 2013
    Applicant: Tengion, Inc.
    Inventors: John W. Ludlow, Manuel J. Jayo, Joydeep Basu, Timothy A. Bertram, Christopher W. Genheimer, Kelly I. Guthrie, Roger M. Ilagan, Deepak Jain, Oluwatoyin A. Knight, Richard Payne, Sarah F. Quinlan, H. Scott Rapoport, Namrata D. Sangha
  • Cell-scaffold constructs
    Patent number: 8337485
    Abstract: The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: December 25, 2012
    Assignee: Tengion, Inc.
    Inventors: John W. Ludlow, Manuel J. Jayo, Joydeep Basu, Timothy A. Bertram, Christopher W. Genheimer, Kelly I. Guthrie, Roger M. Ilagan, Deepak Jain, Oluwatoyin A. Knight, Richard Payne, Sarah F. Quinlan, H. Scott Rapoport, Namrata D. Sangha
  • Isolated renal cells and uses thereof
    Patent number: 8318484
    Abstract: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: November 27, 2012
    Assignee: Tengion, Inc.
    Inventors: Sharon C. Presnell, Andrew Bruce, Shay M. Wallace, Sumana Choudhury, Russell W. Kelley, Manuel J. Jayo, Jessica J. Reinsch, Patricia D. Tatsumi, Timothy A. Bertram, Eric S. Werdin, Oluwatoyin A. Knight, H. Scott Rapoport, Roger M. Ilagan
  • SCAFFOLDS FOR ORGAN RECONSTRUCTION AND AUGMENTATION
    Publication number: 20110257726
    Abstract: Biocompatible synthetic or natural scaffolds are provided for the reconstruction, repair, augmentation or replacement of organs or tissue structures in a patient in need of such treatment. The scaffolds are shaped to conform to at least a part of the organ or tissue structure and may be seeded with one or more cell populations. Inserts, receptacles and ports are also provided for the attachment of tubular vessels to the neo-organ scaffolds. The seeded scaffolds are implanted into the patient at the site in need of treatment to form an organized organ or tissue structure. The scaffolds may be used to form organs or tissues, such as bladders, urethras, valves, and blood vessels.
    Type: Application
    Filed: March 1, 2011
    Publication date: October 20, 2011
    Inventors: Timothy A. Bertram, Andrew Bruce, Deepak Jain, Manuel J. Jayo, John W. Ludlow, Darell McCoy, Richard Payne, Namrata D. Sangha
  • RATIONAL DESIGN OF REGENERATIVE MEDICINE PRODUCTS
    Publication number: 20110123455
    Abstract: The present invention concerns a non-biased, combinatorial approach to the identification of components that modulate a regenerative response in a target tissue, thereby restoring or partially restoring homeostasis to the target tissue. The methods of the present invention are based on in vivo testing, with or without prior in vitro predictive functional testing or combinatorial testing.
    Type: Application
    Filed: November 12, 2010
    Publication date: May 26, 2011
    Inventors: Sharon C. Presnell, Thomas Spencer, Belinda J. Wagner, Manuel J. Jayo, Timothy Bertram, Roger M. Ilagan, Russell W. Kelly, H. Scott Rapoport, Andrew Bruce