Patents by Inventor Manuel Ma

Manuel Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9879300
    Abstract: Disclosed embodiments concern an array for use in identifying or identifying and quantifying analytes in a sample using a macrocyclic sensor comprising a macrocyclic compound and a detectable moiety. The disclosed array may be used to discriminate among various analytes based on different features, such as post-translational modifications, isomeric post-translational modifications, and the peptide sequence around post-translational modifications. Also disclosed is a method for identifying analytes comprising a post-translational modification, as well as an enzymatic assay using the disclosed macrocyclic sensor.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: January 30, 2018
    Assignee: UVic Industry Partnerships
    Inventors: Fraser Hof, Samuel Minaker, Kevin Daze, Sara Tabet, Manuel Ma
  • Publication number: 20140357503
    Abstract: Disclosed embodiments concern an array for use in identifying or identifying and quantifying analytes in a sample using a macrocyclic sensor comprising a macrocyclic compound and a detectable moiety. The disclosed array may be used to discriminate among various analytes based on different features, such as post-translational modifications, isomeric post-translational modifications, and the peptide sequence around post-translational modifications. Also disclosed is a method for identifying analytes comprising a post-translational modification, as well as an enzymatic assay using the disclosed macrocyclic sensor.
    Type: Application
    Filed: June 11, 2014
    Publication date: December 4, 2014
    Applicant: UVic Industry Partnerships Inc.
    Inventors: Fraser Hof, Samuel Minaker, Kevin Daze, Sara Tabet, Manuel Ma
  • Publication number: 20140249380
    Abstract: The present invention relates to an algorithm by which phenotypic features of individuals can be calculated and classified to evaluate the overall health of an individual, and particularly skin aging. More particularly, the present invention relates to methods and systems for diagnosing the perceived age of an individual. The invention also relates to methods useful to define products or treatments to reduce the perceived age, to evaluate the efficacy of products and treatments, and to benchmark the product or treatments in order to determine its market value and customer claims.
    Type: Application
    Filed: February 10, 2014
    Publication date: September 4, 2014
    Applicant: Genocosmetics Lab, SL
    Inventors: José Manuel Mas, Albert Pujol, Jordi Naval, Raquel Valls, Vicent Carles Alonso, Miguel Angel Herranz
  • Patent number: 8580712
    Abstract: Novel bis(dialkylamide) compounds having the formula: R2R3NOC—R1a—CONR4R5 are particularly useful solvents, for example in plant-protection formulations.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: November 12, 2013
    Assignee: Rhodia Operations
    Inventors: Jean-Manuel Mas, Valerio Bramati, Massimo Guglieri, Wagner Celio Ferraz Lourenco
  • Publication number: 20130116215
    Abstract: The invention features novel pharmaceutical combinations useful for the treatment of neurological diseases, specifically neurodegenerative diseases. The novel pharmaceutical combinations of the invention demonstrate additive or synergistic effect in silico and in vivo. The invention also relates to methods of treatment of neurological and neurodegenerative diseases including the pharmaceutical combinations of the invention.
    Type: Application
    Filed: October 25, 2012
    Publication date: May 9, 2013
    Inventors: Mireia Coma, Patrick Aloy, Albert Pujol, Xavier Gomis, Baldomero Oliva, Alberto Lleó, José Manuel Mas
  • Patent number: 8105984
    Abstract: A reduced abrasion drilling fluid system and method of drilling a borehole by circulating the reduced abrasion drilling fluid through the borehole is disclosed. The reduced abrasion drilling fluid comprises a drilling fluid, a first additive and a weighting agent, wherein the weighting agent has a particle size of at least 90% by volume less than 50 ?m.
    Type: Grant
    Filed: January 7, 2009
    Date of Patent: January 31, 2012
    Assignee: Intevep, S.A.
    Inventors: Freddy Quiroga, George Quercia, Richard Rengifo, Manuel Mas
  • Publication number: 20110098993
    Abstract: The present application relates to methods and systems of identifying molecules or processes of biological interest by using knowledge discovery in biological data. In particular, the present application describes new methods of creating a biological map, new methods of codifying such map, new methods of analyzing such map and new methods of identifying molecules and processes of biological interest. The present application provides methods and systems to identify new and useful direct or indirect therapeutic targets, molecular modulators, adverse events effectors, disease biomarkers, genetic biomarkers, safety-related biomarkers, diagnostic molecules, hormones, metabolites, or metabolic effectors of any type.
    Type: Application
    Filed: October 26, 2010
    Publication date: April 28, 2011
    Inventors: Jose Manuel Mas Benavente, Albert Pujol Torras, Patrick Aloy Calaf, Judith Farrés
  • Patent number: 7854263
    Abstract: A surfactant blend for servicing wells includes a first non-ionic surfactant having a hydrophilic-lipophilic balance of between about 10 and about 15; a second non-ionic surfactant having a hydrophilic-lipophilic balance of between about 2 and about 6; and an anionic surfactant.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: December 21, 2010
    Assignee: Intevep, S.A.
    Inventors: Manuel Mas, Alicia Colina, Williams Aular
  • Patent number: 7854802
    Abstract: A surfactant blend for servicing wells includes a first non-ionic surfactant having a hydrophilic-lipophilic balance of between about 10 and about 15; a second non-ionic surfactant having a hydrophilic-lipophilic balance of between about 2 and about 6; and an anionic surfactant.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: December 21, 2010
    Assignee: Intevep, S.A.
    Inventors: Manuel Mas, Alicia Colina, Williams Aular
  • Patent number: 7776988
    Abstract: The invention relates to silicon oils, more particularly, to a novel method for the preparation of a silicon oil by polymerization and rearrangement of cyclic siloxanes in the presence of an alkaline catalyst and a co-catalyst which is a cryptand (macroheterobicyclic diamine) acting as a polymerization accelerator.
    Type: Grant
    Filed: November 30, 2007
    Date of Patent: August 17, 2010
    Assignee: Rhodia Chimie
    Inventors: Etienne Fleury, Jean-Manuel Mas, Kamel Ramdani
  • Publication number: 20100170719
    Abstract: A reduced abrasion drilling fluid system and method of drilling a borehole by circulating the reduced abrasion drilling fluid through the borehole is disclosed. The reduced abrasion drilling fluid comprises a drilling fluid, a first additive and a weighting agent, wherein the weighting agent has a particle size of at least 90% by volume less than 50 ?m.
    Type: Application
    Filed: January 7, 2009
    Publication date: July 8, 2010
    Applicant: Intevep, S.A.
    Inventors: Freddy Quiroga, George Quercia, Richard Rengifo, Manuel Mas
  • Publication number: 20100113279
    Abstract: Novel bis(dialkylamide) compounds having the formula: R2R3NOC—R1a—CONR4R5 are particularly useful solvents, for example in plant-protection formulations.
    Type: Application
    Filed: December 19, 2007
    Publication date: May 6, 2010
    Inventors: Jean-Manuel Mas, Valerio Bramati, Massimo Guglieri, Wagner Celio Ferraz Lourenco
  • Publication number: 20080306236
    Abstract: The invention relates to silicon oils, more particularly, to a novel method for the preparation of a silicon oil by polymerization and rearrangement of cyclic siloxanes in the presence of an alkaline catalyst and a co-catalyst which is a cryptand (macroheterobicyclic diamine) acting as a polymerization accelerator.
    Type: Application
    Filed: November 30, 2007
    Publication date: December 11, 2008
    Applicant: RHODIA CHIMIE
    Inventors: Etienne Fleury, Jean-Manuel Mas, Kamel Ramdani
  • Patent number: 7429620
    Abstract: A surfactant blend for servicing wells includes a first non-ionic surfactant having a hydrophilic-lipophilic balance of between about 10 and about 15; a second non-ionic surfactant having a hydrophilic-lipophilic balance of between about 2 and about 6; and an anionic surfactant.
    Type: Grant
    Filed: August 10, 2004
    Date of Patent: September 30, 2008
    Assignee: Inteveo, S.A.
    Inventors: Manuel Mas, Alicia Colina, Williams Aular
  • Publication number: 20070191234
    Abstract: A surfactant blend for servicing wells includes a first non-ionic surfactant having a hydrophilic-lipophilic balance of between about 10 and about 15; a second non-ionic surfactant having a hydrophilic-lipophilic balance of between about 2 and about 6; and an anionic surfactant.
    Type: Application
    Filed: April 20, 2007
    Publication date: August 16, 2007
    Applicant: INTEVEP, S.A.
    Inventors: Manuel Mas, Alicia Colina, Williams Aular
  • Publication number: 20070191235
    Abstract: A surfactant blend for servicing wells includes a first non-ionic surfactant having a hydrophilic-lipophilic balance of between about 10 and about 15; a second non-ionic surfactant having a hydrophilic-lipophilic balance of between about 2 and about 6; and an anionic surfactant.
    Type: Application
    Filed: April 20, 2007
    Publication date: August 16, 2007
    Applicant: INTEVEP, S.A.
    Inventors: Manuel Mas, Alicia Colina, Williams Aular
  • Publication number: 20060035789
    Abstract: A surfactant blend for servicing wells includes a first non-ionic surfactant having a hydrophilic-lipophilic balance of between about 10 and about 15; a second non-ionic surfactant having a hydrophilic-lipophilic balance of between about 2 and about 6; and an anionic surfactant.
    Type: Application
    Filed: August 10, 2004
    Publication date: February 16, 2006
    Inventors: Manuel Mas, Alicia Colina, Williams Aular
  • Patent number: 6596880
    Abstract: This invention relates to a method for preparing taxane derivatives of general formula (I) by esterification at a temperature between −10 and 60° C. of a derivative of baccatine III or 10-deacetyl baccatine III of general formula (II) by means of an acid of general formula (III), followed by replacement of the protective groupings G1, G2 and R2 of the resulting product by hydrogen atoms. In formulae (I), (II) or (III), Ar stands for an aryl radical; R stands for hydrogen or acetyl; R1 is benzoyl or ter.butoxycarbonyl; G1 is a hydroxy function protective grouping, G2 stands for the acetyl radical or a hydroxy function protective grouping, and R2 stands for a hydroxy function protective grouping.
    Type: Grant
    Filed: August 2, 1994
    Date of Patent: July 22, 2003
    Assignee: Aventis Pharma S.A.
    Inventors: Elie Fouque, Jean-Manuel Mas
  • Patent number: 6464895
    Abstract: The invention relates to a nucleophilic reagent which is useful for grafting a substituted difluoromethyl group onto a compound containing at least one electrophilic function, or for the synthesis of oxysulphide-containing and fluorine-containing organic derivatives, wherein said reagent comprises: a) a fluorocarboxylic acid of formula Ew—CF2—COOH where Ew represents an electron-withdrawing atom or group, at least partially salified with an organic or inorganic cation, and b) a polar aprotic solvent; and in that the content of releasable protons carried by its various components, including their impurities, is at most equal to half the initial molar concentration of the said fluorocarboxylic acid. A synthetic process uses this reagent by heating in order to graft a substituted difluoromethyl group onto various compounds.
    Type: Grant
    Filed: December 1, 1998
    Date of Patent: October 15, 2002
    Assignee: Rhodia Chimie
    Inventors: Gérard Forat, Jean-Manuel Mas, Laurent Saint-Jalmes
  • Patent number: D565378
    Type: Grant
    Filed: October 26, 2006
    Date of Patent: April 1, 2008
    Inventors: Manuel Ma Zubiaurre Alberdi, Pedro José Zubiaurre Alberdi