Patents by Inventor Manuel Mark

Manuel Mark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12203826
    Abstract: A method for operating an exhaust gas sensor in an exhaust system of an internal combustion engine of a vehicle. The exhaust gas sensor includes a ceramic sensor element having at least one measuring electrode and a heating device. A binary dewpoint end signal is calculated, based on data which relate to the internal combustion engine and the exhaust gas sensor, which indicates whether or not the occurrence of liquid water in the exhaust system is still to be expected. Whenever the vehicle is turned off and the dewpoint end signal simultaneously has the value which signals that the occurrence of liquid water in the exhaust system is still to be expected, the sensor element is heated by its heating device to a temperature for a certain period of time in such a way that the sensor element dries.
    Type: Grant
    Filed: July 10, 2020
    Date of Patent: January 21, 2025
    Assignee: ROBERT BOSCH GMBH
    Inventors: Michael Bessen, Dorothea Welke, Felix Guenther, Maik Thiele, Manuel Marks, Mathias Klenk
  • Publication number: 20220326119
    Abstract: A method for operating an exhaust gas sensor in an exhaust system of an internal combustion engine of a vehicle. The exhaust gas sensor includes a ceramic sensor element having at least one measuring electrode and a heating device. A binary dewpoint end signal is calculated, based on data which relate to the internal combustion engine and the exhaust gas sensor, which indicates whether or not the occurrence of liquid water in the exhaust system is still to be expected. Whenever the vehicle is turned off and the dewpoint end signal simultaneously has the value which signals that the occurrence of liquid water in the exhaust system is still to be expected, the sensor element is heated by its heating device to a temperature for a certain period of time in such a way that the sensor element dries.
    Type: Application
    Filed: July 10, 2020
    Publication date: October 13, 2022
    Inventors: Michael Bessen, Dorothea Welke, Felix Guenther, Maik Thiele, Manuel Marks, Mathias Klenk
  • Publication number: 20090187928
    Abstract: The present invention relates to a method that allows master web applications integrated into web slave applications to advertise products or services overcoming limitations related to the reduced advertising space available in the master application. The method also allows users to avoid disruption problems when working simultaneously with master and slave applications.
    Type: Application
    Filed: October 22, 2008
    Publication date: July 23, 2009
    Applicant: REXTIDE INC.
    Inventor: Manuel Mark
  • Publication number: 20090106071
    Abstract: The present invention relates to a method for controlling, planning, managing and enhancing the progressive achievement of user's future goals. The method allows for comparing and interpreting life-event data provided by the user in connection with his or her expected future achievements within a specific timeframe. It also enables ecommerce opportunities for sponsors and advertisers.
    Type: Application
    Filed: October 17, 2008
    Publication date: April 23, 2009
    Applicant: Rextide Inc.
    Inventor: Manuel Mark
  • Patent number: 6521814
    Abstract: The invention relates to methods for treatment of neurological disease by administering an agent which interacts with a retinoid receptor associated with the neurological disease. The invention is also related to a method of modulating dopamine receptor synthesis by introducing an agent that interacts with a retinoid receptor associated with the dopamine receptor synthesis. The invention is further related to a transgenic animal, e.g., mouse, and mammalian cell line, which is deficient in the normal synthesis of one or more receptors of RAR&agr;, &bgr;, &ggr; and RXR, and cell line thereof.
    Type: Grant
    Filed: December 22, 1998
    Date of Patent: February 18, 2003
    Assignees: Institut National de la Santa et de la Recherche Medicale, Centre National de la Recherche Scientifique, Universite Louis Pasteur, Bristol-Myers Squibb Company
    Inventors: Pierre Chambon, Emiliana Borrelli, Norbert B. Ghyselinck, Valérie Dupé, Manuel Mark, Daniel Metzger
  • Patent number: 6486381
    Abstract: The present invention provides mice which are deficient in the normal expression of one or more members of the RAR or RXR class of receptors, to mice heterozygous for such deficiency, and to cell lines, preferably pluripotent or totipotent cell lines, which are heterozygous or homozygous for such deficiency. The present invention further provides the use of any of the above mice and cell lines in situations where the absence of at least one RAR or RXR receptors, or the normal expression thereof, is desirable.
    Type: Grant
    Filed: October 26, 1999
    Date of Patent: November 26, 2002
    Assignees: Institut National de la Sante et de la Recherche Medicale, Centre National de la Recherche Scientifique, Universite Louis Pasteur, Bristol Myers Squibb Company
    Inventors: Pierre Chambon, Thomas Lufkin, David Lohnes, Manuel Mark, Andree Dierich, Philippe Gorry, Philippe Kastner, Marianne Lemeur, Cathy Mendelsohn
  • Publication number: 20020048580
    Abstract: The invention relates to a method of treating lung branching malformation in a subject by administering to the subject a pharmaceutically effective amount of a retinoic acid receptor (RAR) retinoid. The invention also relates to a method of increasing alveoli in a subject by administering a pharmaceutically effective amount of a retinoic acid receptor (RAR) antagonist. The invention further relates to a method of inducing primary lung bud formation in a subject by administering a pharmaceutically effective amount of a retinoic acid receptor agonist. The invention also relates to a method of identifying an agent capable of inducing primary lung bud formation, the method comprising: (a) administering an agent to an embryo; and (b) determining primary lung bud formation of said embryo.
    Type: Application
    Filed: June 7, 2001
    Publication date: April 25, 2002
    Applicant: Institut National De La Sante Et De La Recherche Medicale
    Inventors: Richard Mollard, Pierre Chambon, Manuel Mark
  • Patent number: 6030794
    Abstract: The present invention provides mice which are deficient in the normal expression of one or more members of the RAR or RXR class of receptors, mice which are heterozygous for such deficiency, and to cell lines, preferably pluripotent or totipotent cell lines, which are heterozygous or homozygous for such deficiency. The present invention further provides the use of any of the above mice and cell lines in situations where the absence of at least one RAR or RXR receptor(s), or the normal expression thereof, is desirable.
    Type: Grant
    Filed: June 27, 1995
    Date of Patent: February 29, 2000
    Assignees: Institut National de la Sante et de la Recherche Medicale, Centre National de la Recherche Scientifique, Universite Louis Pasteur, E. R. Squibb & Sons, Inc.
    Inventors: Pierre Chambon, Thomas Lufkin, David Lohnes, Manuel Mark, Andree Dierich, Philippe Gorry, Philippe Kastner, Marianne Lemeur, Cathy Mendelsohn
  • Patent number: 6031149
    Abstract: The present invention provides mice which are deficient in the normal expression of one or more members of the RAR or RXR class of receptors, to mice heterozygous for such deficiency, and to cell lines, preferably pluripotent or totipotent cell lines, which are heterozygous or homozygous for such deficiency. The present invention further provides the use of any of the above mice and cell lines in situations where the absence of at least one RAR or RXR receptors, or the normal expression thereof, is desirable.
    Type: Grant
    Filed: December 29, 1995
    Date of Patent: February 29, 2000
    Assignees: Institut National De La Sante Et De La Recherche Medicale, Centre National De La Recherche Scientifique, Universite Louis Pasteur, E.R. Squibb & Sons, Inc.
    Inventors: Pierre Chambon, Thomas Lufkin, David Lohnes, Manuel Mark, Andree Dierich, Philippe Gorry, Philippe Kastner, Marianne Lemeur, Cathy Mendelsohn