Abstract: A system and method for routing electronic content to a recipient device comprising a plurality of network nodes, each network node adapted to receive and forward electronic content and an activity profile server adapted to be in data communication with each network node, the activity profile server adapted to monitor the activity level of each network node and inform each network node on the congestion level of an adjacent network node; wherein each network node is adapted, on receiving the information on congestion level to store electronic content if the adjacent network node is congested and forward the electronic content to the adjacent network node if the adjacent network node is not congested is disclosed.

Abstract: A system and method for routing electronic content to a recipient device comprising a plurality of network nodes, each network node adapted to receive and forward electronic content and an activity profile server adapted to be in data communication with each network node, the activity profile server adapted to monitor the activity level of each network node and inform each network node on the congestion level of an adjacent network node; wherein each network node is adapted, on receiving the information on congestion level to store electronic content if the adjacent network node is congested and forward the electronic content to the adjacent network node if the adjacent network node is not congested is disclosed.

Abstract: A broadcast program content recognition system comprising at least one receiver adapted to sample broadcast program content from a broadcast source; a content recognition engine for recognizing and storing the sampled broadcast program content; and a content database in data communication with the content recognition means; the content database adapted to return information relating to the broadcast program content upon receipt of a query from a client device is disclosed. The system is configured such that in event where the content recognition engine is unable to recognize the sample broadcast program content, the content recognition engine splits the unrecognized sample into at least a first and a second sequential portions and appends the first portion to a previously recognized sample.

Abstract: Disclosed is a series of nucleic acid probes for use in diagnosing and monitoring certain types of leukemia using, e.g., Southern and Northern blot analyses and fluorescence in situ hybridization (FISH). These probes detect rearrangements, such as translocations involving chromosome band 11q23 with other chromosomes bands, including 4q21, 6q27, 9p22, 19p13.3, in both dividing leukemic cells and interphase nuclei. The breakpoints in all such translocations are clustered within an 8.3 kb BamHI genomic region of the MLL gene. A novel 0.7 kb BamH1 cDNA fragment derived from this gene detects rearrangements on Southern blot analysis with a single BamHI restriction digest in all patients with the common 11q23 translocations and in patients with other 11q23 anomalies. Northern blot analyses are presented demonstrating that the MLL gene has multiple transcripts and that transcript size differentiates leukemic cells from normal cells. Also disclosed are MLL fusion proteins, MLL protein domains and anti-MLL antibodies.

Abstract: Disclosed is a series of nucleic acid probes for use in diagnosing and monitoring certain types of leukemia using, e.g., Southern and Northern blot analyses and fluorescence in situ hybridization (FISH). These probes detect rearrangements, such as translocations involving chromosome band 11q23 with other chromosomes bands, including 4q21, 6q27, 9p22, 19p13.3, in both dividing leukemic cells and interphase nuclei. The breakpoints in all such translocations are clustered within an 8.3 kb BamHI genomic region of the MLL gene. A novel 0.7 kb BamHI cDNA fragment derived from this gene detects rearrangements on Southern blot analysis with a single BamHI restriction digest in all patients with the common 11q23 translocations and in patients with other 11q23 anomalies. Northern blot analyses are presented demonstrating that the MLL gene has multiple transcripts and that transcript size differentiates leukemic cells from normal cells. Also disclosed are MLL fusion proteins, MLL protein domains and anti-MLL antibodies.