Abstract: The disclosure relates to a liquid pharmaceutical composition of aldesleukin/SDS aggregates and its use in the treatment of auto-immune disease, inflammatory disorders, gene therapies and cancer. A method for preparing said composition is also described.

Abstract: An approach for enhancing a video stream. The approach processes a video stream and identifies frames comprising text. The approach marks text extraction locations and extracts the text from the frames. The approach determines if a mirroring effect should be applied to the text and applies if applicable, creating enhanced text. The approach inserts the enhanced text and smooths the edges of the inserted enhanced text. The approach merges the frames with the enhanced text into the video stream, creating an enhanced video stream and sends the enhanced video stream to requesting users.

Abstract: The present disclosure relates to image processing or computer vision techniques. A computer-implemented method is provided for determining a damage status of a physical object, the method comprising the steps of receiving a surface image of the physical object; and providing a pre-trained machine learning model to derive property values from the received surface map, wherein each property value is indicative of a damage index at a respective location, wherein the property values are preferably usable for monitoring and/or controlling a production process of the physical object. In this way, it is possible to reliably identify local defects and ensure that it is accurate enough to apply the chemical products in suitable amounts.

Abstract: The disclosure relates to an optical system for capturing information on the two-dimensional and/or three-dimensional distribution of wavefronts from a plurality of images, wherein the optical system comprises at least one sensor for capturing images, wherein the at least one sensor comprises a plurality of pixels and wherein at least some of the pixels comprise at least two photodiodes; at least one tunable optical element, wherein said at least one tunable optical element is adapted to vary the focus of the optical system; and wherein the optical system is configured for capturing a plurality of images with the at least one sensor at a plurality of focus positions set by the at least one tunable optical element.

Abstract: In some examples, a computing device is able to communicate with a plurality of data clusters. For example, a first data cluster may be configured with a first version of data cluster software including a first library version, and a second data cluster may be configured with a second version of data cluster software including a second library version that is different from the first. The computing device may execute a single instance of an application to send, based at least on information in the first library version, to the first data cluster, a request for first data, and may receive the first data from the first cluster. Further, the computing device may send, based at least on information in the second library version, second data that is based on the first data to the second data cluster to store the second data with the second data cluster.

Abstract: The present invention relates to compounds, compositions, and combined preparations for the treatment of hepatocellular carcinoma, diagnostic methods, and methods for selecting therapeutic agents useful in the prevention, improvement, relief, and/or treatment of hepatocellular carcinoma.

Abstract: The invention relates to a liquid pharmaceutical composition of aldesleukin/SDS aggregates and its use in the treatment of auto-immune disease, inflammatory disorders and cancer. A method for preparing said composition is also described.

Abstract: A method for storing of at least one dataset in a distributed data processing network includes: sending, from a specific network node to all close network nodes, an ADD message for adding a value to a dataset, wherein the ADD message comprises the key of the dataset and the value to be added; based on a close network node receiving the ADD message and the key not being known to the close network node, creating a new dataset in an internal table of the close network node comprising the key and the value; and based on the close network node receiving the ADD message and the key being known to the close network node, adding the value to the one or more values in the dataset of the key in the internal table of the close network.

Abstract: Methods, systems, and non-transitory computer readable storage media are disclosed for utilizing a multi-stroke neural network for modifying a digital image via a plurality of generated stroke parameters in a single pass of the neural network. Specifically, the disclosed system utilizes an encoder neural network to generate an encoding of a digital image. The disclosed system then utilizes a decoder neural network that generates a sequence of stroke parameters for digital drawing strokes from the encoding in a single pass of the encoder neural network and decoder neural network. Additionally, the disclosed system utilizes a renderer neural network to render the digital drawing strokes on a digital canvas according to the sequence of stroke parameters. In additional embodiments, the disclosed system utilizes a balance of loss functions to learn parameters of the multi-stroke neural network to generate stroke parameters according to various rendering styles.

Abstract: The disclosure relates to a method for characterizing and operating a display, such as a light-field display or a display with or without a phase screen, comprising: an input stage wherein at least one test signal is provided as input to the display, a capture stage for obtaining display output information, said capture stage comprising capturing, by at least one acquisition system placed at a distance from the display, an impulse response of the display in response to the at least one provided test signal, wherein said capturing of an impulse response comprises measuring the at the at least one acquisition system received intensity distribution of the light emitted by the display in response to the at least one test signal, and/or capturing the wavefront phase of the light emitted by the display in response to the at least one test signal.

Abstract: Apparatus, systems, and methods for real-time gait modulation are disclosed. In one embodiment, a functional electrical stimulation (FES) device is disclosed comprising one or more wearable articles, a control unit comprising a wireless communication module, one or more processors, one or more memory units, a portable power supply, an electrical muscle stimulation (EMS) generator, and an inertial measurement unit (IMU) comprising at least a gyroscope and an accelerometer. The FES device can also comprise one or more electrode arrays configured to be in physical contact with the limb of the user. The processors can be programmed to execute instructions to retrieve readings from the IMU, calculate a gait cycle percentage by inputting at least the IMU readings into a machine learning algorithm, and instruct the EMS generator to provide electrical stimulation via the one or more electrode arrays based in part on the gait cycle percentage calculated.

Abstract: The present invention relates to immunogenic polypeptides, immunogenic fragments thereof and compositions comprising same, for use in eliciting an immune response in a subject to a tick. The invention also provides for methods of using said compositions and polypeptides.

Abstract: In some examples, a computing device is able to communicate with a plurality of data clusters. For example, a first data cluster may be configured with a first version of data cluster software including a first library version, and a second data cluster may be configured with a second version of data cluster software including a second library version that is different from the first. The computing device may execute a single instance of an application to send, based at least on information in the first library version, to the first data cluster, a request for first data, and may receive the first data from the first cluster. Further, the computing device may send, based at least on information in the second library version, second data that is based on the first data to the second data cluster to store the second data with the second data cluster.

Abstract: A method for transport of messages includes: based on relay-flag information being set to the first value, sending a message directly from a sending network node to a receiving network node, and sending an acknowledgement message directly from the receiving network node to the sending network node; based on relay-flag information being set to the second value, relaying a message from the sending network node via a third network node to the receiving network node, and sending an acknowledgement message directly from the receiving network node to the sending network node; and based on relay-flag information being set to the third value, relaying a message from the sending network node via a third network node to the receiving network node, and relaying an acknowledgement message from the receiving network node via the third network node to the sending network node.

Abstract: The disclosure relates to a method including: capturing a sequence of images of a scene with a camera at different focus positions according to a predetermined focus schedule that specifies a chronological sequence of focus positions of the camera, extracting image features of captured images, after having extracted and stored image features from said captured images, processing a captured image whose image features have not yet been extracted, said processing comprising extracting image features from the currently processed image and storing the extracted image features, said processing further comprising aligning image features stored from the previously captured images with the image features of the currently processed image, and generating a multi-dimensional tensor representing the image features of the processed images aligned to the image features of the currently processed image, and generating a two-dimensional depth map using the focus positions in the predetermined focus schedule and the generated

Abstract: Apparatus, systems, and methods for real-time gait modulation are disclosed. In one embodiment, a functional electrical stimulation (FES) device is disclosed comprising one or more elastic wearable articles, a control unit comprising a wireless communication module, one or more processors, one or more memory units, a portable power supply, an electrical muscle stimulation (EMS) generator, and an inertial measurement unit (IMU) comprising at least a gyroscope and an accelerometer. The FES device can also comprise one or more electrode arrays configured to be in physical contact with the limb of the user. The processors can be programmed to execute instructions to retrieve readings from the IMU, calculate a gait cycle percentage by inputting at least the IMU readings into a machine learning algorithm, and instruct the EMS generator to provide electrical stimulation via the one or more electrode arrays based in part on the gait cycle percentage calculated.

Abstract: An antenna assembly is provided. The antenna assembly includes a tube structure disposed on a circuit board. The antenna assembly further includes a helical antenna comprising a plurality of conductive traces disposed on a flexible substrate wrapped around the tube structure.

Abstract: An antenna assembly can be configured for RF communications. The antenna assembly can include a ground plane disposed on a substrate. The antenna assembly can include a patch antenna structure spaced apart from the ground plane. The antenna assembly can include one or more grounded posts coupled to and extending from the substrate. The one or more grounded posts can be arranged along at least a portion of a periphery of the patch antenna structure. The patch antenna structure can emit a radiation pattern based at least in part on a transmit signal. The radiation pattern can induce a resultant field in the one or more grounded posts to adjust a characteristic of the radiation pattern.

Abstract: The invention relates to a computer-implemented method for detecting barcodes in a digital image represented as a two-dimensional digital image array comprising: applying a filter to the image array, computing a discrete Radon transformation of the filtered image array, wherein the discrete Radon Transformation is computed for a plurality of discrete lines across the filtered image array, wherein for each given discrete line with a given slope the discrete Radon transformation is computed for a number of different displacements of the given discrete line, wherein said number of displacements is less than two times a dimension of the image array, detecting in the output of the discrete Radon transformation of the filtered image array the vertex points of a pattern, and converting the detected vertex points back to discrete lines in the image array for constraining the location of a barcode present in the digital image.

Abstract: Methods are provided for determining prognosis of multiple myeloma in a patient by measuring expression of BCMA in a sample. Also provided are methods for treating multiple myeloma by measuring expression of BCMA in a sample and administering an effective amount of an antigen binding protein that binds BCMA. Also provided are kits for measuring BCMA expression in a sample.