Patents by Inventor Manuel Thomas

Manuel Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11958912
    Abstract: Herein is reported a method for determining the binding interaction with a multimeric antigen of an antibody of the human IgG1 subclass that has at least two binding sites specifically binding to the antigen comprising the steps of 1) determining the binding affinity of the antibody for the multimeric antigen, and 2) incubating a mixture comprising the antibody and a polypeptide that is derived from lysine-gingipain of Porphyromonas gingivalis under conditions and for a time sufficient to cleave the antibody into Fabs and Fc-region, and determining the binding affinity of the Fabs of the antibody for the multimeric, whereby the binding affinity of the antibody to the multimeric antigen to be affinity-driven if the binding affinity determined in both steps are comparable and to be avidity-driven if the binding affinity determined in both steps are different.
    Type: Grant
    Filed: October 2, 2020
    Date of Patent: April 16, 2024
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Joerg Moelleken, Michael Molhoj, Christian Gassner, Manuel Endesfelder, Joerg-Thomas Regula
  • Publication number: 20240084452
    Abstract: A tray for a vaporization vessel that includes a tray having a side wall, a bottom plate, one or more apertures that extend through the bottom plate, and a duct that extends through and from the bottom plate. The tray configured to support a solid reagent to be vaporized. A method of assembling the tray that includes forming a first tray that has the side wall and the bottom plate. A vaporization vessel that includes one or more of the trays.
    Type: Application
    Filed: October 13, 2023
    Publication date: March 14, 2024
    Inventors: Bryan C. HENDRIX, Scott L. Battle, David J. Eldridge, John N. Gregg, Jacob Thomas, Manuel F. Gonzales, Kenney R. Jordan, Benjamin H. Olson
  • Patent number: 11921911
    Abstract: A peripheral device, for use with a host, comprises one or more compute elements a security module and at least one encryption unit. The security module is configured to form a trusted execution environment on the peripheral device for processing sensitive data using sensitive code. The sensitive data and sensitive code are provided by a trusted computing entity which is in communication with the host computing device. The at least one encryption unit is configured to encrypt and decrypt data transferred between the trusted execution environment and the trusted computing entity via the host computing device. The security module is configured to compute and send an attestation to the trusted computing entity to attest that the sensitive code is in the trusted execution environment.
    Type: Grant
    Filed: July 13, 2021
    Date of Patent: March 5, 2024
    Assignee: Microsoft Technology Licensing, LLC.
    Inventors: Stavros Volos, David Thomas Chisnall, Saurabh Mohan Kulkarni, Kapil Vaswani, Manuel Costa, Samuel Alexander Webster, Cédric Alain Marie Fournet, Richard Osborne, Daniel John Pelham Wilkinson, Graham Bernard Cunningham
  • Patent number: 11732509
    Abstract: A ring hoop padlock comprises a ring hoop rotatable about an axis of rotation; a lock cylinder that has a cylinder housing and a rotatable cylinder core; an entrainer coupled to the cylinder core for driving the ring hoop; a housing that has a front housing part and a rear housing part; and an insertion part in which the lock cylinder is held, with the insertion part being integrally formed in one piece.
    Type: Grant
    Filed: August 31, 2020
    Date of Patent: August 22, 2023
    Assignee: ABUS AUGUST BREMICKER SÖHNE KG
    Inventors: Martin Hommel, Michael Diesing, Manuel Thomas
  • Patent number: 11214988
    Abstract: A lockout padlock for securing a switch of an industrial plant comprises a lock housing composed of plastic, a hoop, a lock cylinder that has a cylinder housing and a rotatable cylinder core, and a key, with the cylinder core being rotatable between a locked position in which the hoop is locked or lockable to the lock housing and an unlocked position. The lock cylinder has a plurality of tumblers, with each tumbler being movable between a respective release position and a respective blocking position. The plurality of tumblers comprise a plurality of pin tumblers that are spring-loaded in the direction of their respective blocking positions. The plurality of tumblers furthermore comprise a plurality of supplementary tumblers that are not spring-loaded and that are freely movably supported between their respective release positions and their respective blocking positions.
    Type: Grant
    Filed: April 22, 2019
    Date of Patent: January 4, 2022
    Assignee: ABUS August Bremicker Soehne KG
    Inventors: Wai Kuen Fan, Bernhard Garthe, Manuel Thomas
  • Publication number: 20210131146
    Abstract: A lock, in particular a bicycle lock, includes a lock body, a locking element located outside the lock body, and a locking mechanism located outside the lock body for receiving and locking the locking element. The locking mechanism is connected to the lock body by a first rope section and the locking element is connected to the lock body by a second rope section. A length of a part of at least one of the rope sections extending outside the lock body is variable.
    Type: Application
    Filed: November 4, 2020
    Publication date: May 6, 2021
    Inventors: Marcus Kuchler, Manuel Thomas
  • Publication number: 20210071445
    Abstract: A ring hoop padlock comprises a ring hoop rotatable about an axis of rotation; a lock cylinder that has a cylinder housing and a rotatable cylinder core; an entrainer coupled to the cylinder core for driving the ring hoop; a housing that has a front housing part and a rear housing part; and an insertion part in which the lock cylinder is held, with the insertion part being integrally formed in one piece.
    Type: Application
    Filed: August 31, 2020
    Publication date: March 11, 2021
    Inventors: Martin HOMMEL, Michael DIESING, Manuel THOMAS
  • Publication number: 20190323268
    Abstract: A lockout padlock for securing a switch of an industrial plant comprises a lock housing composed of plastic, a hoop, a lock cylinder that has a cylinder housing and a rotatable cylinder core, and a key, with the cylinder core being rotatable between a locked position in which the hoop is locked or lockable to the lock housing and an unlocked position. The lock cylinder has a plurality of tumblers, with each tumbler being movable between a respective release position and a respective blocking position. The plurality of tumblers comprise a plurality of pin tumblers that are spring-loaded in the direction of their respective blocking positions. The plurality of tumblers furthermore comprise a plurality of supplementary tumblers that are not spring-loaded and that are freely movably supported between their respective release positions and their respective blocking positions.
    Type: Application
    Filed: April 22, 2019
    Publication date: October 24, 2019
    Inventors: Wai Kuen FAN, Bernhard Garthe, Manuel Thomas
  • Patent number: 9388606
    Abstract: A cable locking system comprises a housing, a cable whose one end is fastened or fastenable to the housing and whose other end can be introduced into a cable passage formed in the housing, a clamping device for clamping the cable in the cable passage and an actuation element which is adjustable between a closed position, in which the actuation element is fastenable to the housing by means of locking elements, in particular padlocks, and an open position in order selectively to adjust at least one clamp jaw of the clamping device between a holding position clamping the cable in the cable passage and a release position releasing the cable. The adjustment of the clamp jaw between the holding position and the release position comprises a pivot movement.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: July 12, 2016
    Assignee: ABUS AUGUST BREMICKER SOHNE KG
    Inventors: Bernhard Garthe, Manuel Thomas
  • Patent number: 9322196
    Abstract: A padlock for securing a switch of an industrial plant comprises a lock body and a hoop which is displaceably held at the lock body, wherein the lock body has a lock housing composed of plastic, a lock cylinder having a rotatable cylinder core, and a rotatable latching member, wherein the cylinder core and the latching member are rotationally fixedly coupled to one another by means of a coupling element and wherein the latching member is rotatable from a release position into a latching position to lock the hoop at the lock body. The padlock is characterized in that the coupling element has at least one first bearing section, one second bearing section and therebetween a shaft section between the latching member and the lock cylinder, said shaft section connecting the first bearing section to the second bearing section and having a smaller diameter than the two bearing sections.
    Type: Grant
    Filed: April 21, 2014
    Date of Patent: April 26, 2016
    Assignee: ABUS August Bremicker Söhne KG
    Inventors: Bernhard Garthe, Wai Kuen Fan, Manuel Thomas
  • Publication number: 20150315822
    Abstract: A cable locking system comprises a housing, a cable whose one end is fastened or fastenable to the housing and whose other end can be introduced into a cable passage formed in the housing, a clamping device for clamping the cable in the cable passage and an actuation element which is adjustable between a closed position, in which the actuation element is fastenable to the housing by means of locking elements, in particular padlocks, and an open position in order selectively to adjust at least one clamp jaw of the clamping device between a holding position clamping the cable in the cable passage and a release position releasing the cable. The adjustment of the clamp jaw between the holding position and the release position comprises a pivot movement.
    Type: Application
    Filed: April 30, 2015
    Publication date: November 5, 2015
    Inventors: Bernhard GARTHE, Manuel THOMAS
  • Publication number: 20140311196
    Abstract: A padlock for securing a switch of an industrial plant comprises a lock body and a hoop which is displaceably held at the lock body, wherein the lock body has a lock housing composed of plastic, a lock cylinder having a rotatable cylinder core, and a rotatable latching member, wherein the cylinder core and the latching member are rotationally fixedly coupled to one another by means of a coupling element and wherein the latching member is rotatable from a release position into a latching position to lock the hoop at the lock body. The padlock is characterized in that the coupling element has at least one first bearing section, one second bearing section and therebetween a shaft section between the latching member and the lock cylinder, said shaft section connecting the first bearing section to the second bearing section and having a smaller diameter than the two bearing sections.
    Type: Application
    Filed: April 21, 2014
    Publication date: October 23, 2014
    Applicant: ABUS August Bremicker Söhne KG
    Inventors: Bernhard Garthe, Wai Kuen Fan, Manuel Thomas
  • Patent number: 8151604
    Abstract: The invention relates to a loop lock, in particular to a chain lock or to a wire cable lock, having a lock body which has a longitudinal axis and which surrounds a cylinder housing of a lock cylinder and having a loop, wherein the first end of the loop is permanently fastened to a fastening point of the cylinder housing and is aligned perpendicular to the longitudinal axis of the lock body, wherein a second end of the loop can be releasably fastened to a longitudinal end of the lock body and is aligned coaxially to the longitudinal axis of the lock body; and wherein a cylinder core of the lock cylinder is rotatably journalled about an axis of rotation in the cylinder housing and is characterized in that the axis of rotation of the cylinder core is offset in parallel with respect to the longitudinal axis of the lock body, namely away from the fastening point for the first end of the loop.
    Type: Grant
    Filed: August 24, 2010
    Date of Patent: April 10, 2012
    Assignee: ABUS August Bremicker Soehne KG
    Inventors: Manuel Thomas, Hoi Jarm Ng, Wai Leung Ng, legal representative
  • Publication number: 20110048082
    Abstract: The invention relates to a loop lock, in particular to a chain lock or to a wire cable lock, having a lock body which has a longitudinal axis and which surrounds a cylinder housing of a lock cylinder and having a loop, wherein the first end of the loop is permanently fastened to a fastening point of the cylinder housing and is aligned perpendicular to the longitudinal axis of the lock body, wherein a second end of the loop can be releasably fastened to a longitudinal end of the lock body and is aligned coaxially to the longitudinal axis of the lock body; and wherein a cylinder core of the lock cylinder is rotatably journalled about an axis of rotation in the cylinder housing and is characterized in that the axis of rotation of the cylinder core is offset in parallel with respect to the longitudinal axis of the lock body, namely away from the fastening point for the first end of the loop.
    Type: Application
    Filed: August 24, 2010
    Publication date: March 3, 2011
    Applicant: ABUS August Bremicker Soehne KG
    Inventors: Manuel Thomas, Hoi Jarm Ng, Wai Leung Ng
  • Patent number: 5398492
    Abstract: Industrial dust mop having a homogenous yarn composed of high melt staple fibers and low melt staple which has been heated to homogeneously melt the low melt fibers throughout the yarn to form a fused yarn product in the mop.
    Type: Grant
    Filed: April 16, 1993
    Date of Patent: March 21, 1995
    Assignee: Milliken Research Corporation
    Inventor: Manuel A. Thomas
  • Patent number: 5397622
    Abstract: Industrial dust mop having a homogenous yarn composed of high melt staple fibers and low melt staple which has been heated to homogeneously melt the low melt fibers throughout the yarn to form a fused yarn product in the mop.
    Type: Grant
    Filed: May 2, 1994
    Date of Patent: March 14, 1995
    Assignee: Milliken Research Corporation
    Inventor: Manuel A. Thomas
  • Patent number: 4131422
    Abstract: Polymer-printed fabrics are produced by applying to a textile fabric substrate, in a pre-determined pattern, an aqueous admixture consisting essentially of from about 1 and to about 45 percent of a substantially water-soluble acid dyeable polymer having a cationic charge in milliequivalents/gram of polymer of from about 0.01 to about 5. The aqueous admixture is further characterized as having a viscosity of from about 5 to about 50,000 centipoise. The wetted printed substrate is dried to remove substantially all the water and thereafter cured. The cured polymer printed substrate is then dyed with a dye admixture containing an acid dyestuff preferential to the polymer coated portion of the substrate.
    Type: Grant
    Filed: February 22, 1977
    Date of Patent: December 26, 1978
    Assignee: Milliken Research Corporation
    Inventors: Manuel A. Thomas, Jerry A. Cogan, Jr.