Patents by Inventor Manuel Valiente

Manuel Valiente has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATING METASTATIC CANCER AND MODEL SYSTEMS FOR METASTATIC DISEASE
    Publication number: 20250213731
    Abstract: The present invention relates to methods and compositions for inhibiting metastatic spread of cancer and/or inhibiting progression of pre-existing metastatic disease in a subject using L1CAM inhibition.
    Type: Application
    Filed: August 12, 2024
    Publication date: July 3, 2025
    Applicant: Memorial Sloan-Kettering Cancer Center
    Inventors: Karuna Ganesh, Manuel Valiente, Joan Massague
  • Treating metastatic cancer and model systems for metastatic disease
    Patent number: 12059480
    Abstract: The present invention relates to methods and compositions for inhibiting metastatic spread of cancer and/or inhibiting progression of pre-existing metastatic disease in a subject using L1CAM inhibition.
    Type: Grant
    Filed: October 10, 2022
    Date of Patent: August 13, 2024
    Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Karuna Ganesh, Manuel Valiente, Joan Massague
  • TREATING METASTATIC CANCER AND MODEL SYSTEMS FOR METASTATIC DISEASE
    Publication number: 20230190963
    Abstract: The present invention relates to methods and compositions for inhibiting metastatic spread of cancer and/or inhibiting progression of pre-existing metastatic disease in a subject using L1CAM inhibition.
    Type: Application
    Filed: October 10, 2022
    Publication date: June 22, 2023
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Karuna Ganesh, Manuel Valiente, Joan Massague
  • Treating metastatic cancer and model systems for metastatic disease
    Patent number: 11464874
    Abstract: The present invention relates to methods and compositions for inhibiting metastatic spread of cancer and/or inhibiting progression of pre-existing metastatic disease in a subject using L1CAM inhibition.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: October 11, 2022
    Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Karuna Ganesh, Manuel Valiente, Joan Massague
  • TREATING METASTATIC CANCER AND MODEL SYSTEMS FOR METASTATIC DISEASE
    Publication number: 20190167817
    Abstract: The present invention relates to methods and compositions for inhibiting metastatic spread of cancer and/or inhibiting progression of pre-existing metastatic disease in a subject using L1CAM inhibition.
    Type: Application
    Filed: January 31, 2019
    Publication date: June 6, 2019
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Karuna Ganesh, Manuel Valiente, Joan Massague
  • INHIBITING CANCER METASTASIS
    Publication number: 20160194639
    Abstract: The present invention relates to methods and compositions for determining whether a cancer patient is at increased risk for developing metastatic spread of the cancer and, if the patient is at increased risk, for treating the patient such that the risk of metastasis is reduced. It is based, at least in part, on the discoveries that overexpression of serpin and serpin secretion by cancer cells and L1CAM-mediated vascular cooption promote metastasis of lung and breast cancer to the brain, and that antagonism of serpin or L1CAM reduced metastasis.
    Type: Application
    Filed: March 18, 2016
    Publication date: July 7, 2016
    Applicant: MEMORIAL SLOAN KETTERING CANCER CENTER
    Inventors: Joan Massague, Manuel Valiente