Abstract: The present invention relates to methods and compositions for inhibiting metastatic spread of cancer and/or inhibiting progression of pre-existing metastatic disease in a subject using L1CAM inhibition.

Abstract: The present invention relates to a tooth whitening composition, which comprises a reducing agent partially encapsulated in liposomes. It relates also to a method for preparing that tooth whitening composition and to the non-therapeutic cosmetic use of that composition for tooth whitening.

Abstract: The present invention relates to methods and compositions for inhibiting metastatic spread of cancer and/or inhibiting progression of pre-existing metastatic disease in a subject using L1CAM inhibition.

Abstract: The present invention relates to methods and compositions for inhibiting metastatic spread of cancer and/or inhibiting progression of pre-existing metastatic disease in a subject using L1CAM inhibition.

Abstract: The invention relates to a new method for Arsenic adsorption-desorption and sorbent regeneration with no reagents added by taking advantage of the synergic thermo tuning of redox potential of the adsorption-desorption system.

Abstract: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

Abstract: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

Abstract: The present invention relates to methods and compositions for determining whether a cancer patient is at increased risk for developing metastatic spread of the cancer and, if the patient is at increased risk, for treating the patient such that the risk of metastasis is reduced. It is based, at least in part, on the discoveries that overexpression of serpin and serpin secretion by cancer cells and L1CAM-mediated vascular cooption promote metastasis of lung and breast cancer to the brain, and that antagonism of serpin or L1CAM reduced metastasis.

Abstract: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

Abstract: Liquid treatment filter with magnetite nanoparticles and corresponding methods. Liquid treatment filter comprising a support made of a polymeric material having at least one functional group of the group made up of carboxyl and thiol, loaded with SPION (SuperParamagnetic Iron Oxide Nanoparticles). The support is advantageously made of fibres of hydrolysed polyacrylonitrile of general formula wherein n has a value comprised between 0.01 and 1, and wherein the method for manufacturing comprises: [a] a step of electrospinning in which a solution of polyacrylonitrile is prepared in a solvent with a polyacrylonitrile content comprised between 5 and 80% by weight, with respect to the total weight of the solution, [b] a step of hydrolysis of the PAN fibres formed in step [a], and [c] a step of loading the fibres with SPION.

Abstract: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

Abstract: Setting time accelerator compositions for Portland type cements include two of the following compounds: a) CaCl2, b) Phosphate, c) Silica, that may be used in a dental coating.

Abstract: Comprises a surfactant a cellulose derivative, additives and at least one resin charged with Ca+2, F−, PO43 oZn+2 cations or anions, with the calcium, fluoride and phosphate ions in a molar ratio of 2:1:1 and the zinc ions in dry-weight proportion with respect to the resin or resins of between 0.5 and 2%. It is used as a dental-tissue remineralising agent or for making a medicine for the treatment of buccal diseases and, in particular, for the treatment of caries.

Abstract: Together with other accessory products, includes a mixture of ion-exchange resins, cationic and anionic, charged with Ca2+, F− and PO43− ions, in an approximate molar ratio of 2:1:1, respectively. Particularly preferred is a material in which the resins also have a charge of Zn2+ ions representing a proportion of less than 1%, preferably close to 0.2% of the dry weight of the resin. The preferred resins are those whose base is cross-linked polystyrene with 2-14% divinylbenzene. The material is useful as first filler in the treatment of caries, especially deep caries, leading to remineralization of the dentin with a composition very close to the original composition, together with high microhardness. It is also useful as a component of dentifrice products such as pastes, elixirs and dental floss.