Patents by Inventor Manuel Zapata

Manuel Zapata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220168436
    Abstract: Drug conjugates of formula [D-(X)b-(AA)w-(L)-]n-Ab wherein: D is a drug moiety having the following formula (I) or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof, wherein: A is selected from R1, R2 and R3 is H, ORa, OCORa, OCOORa, alkyl, alkenyl, alkynyl, etc; R3? is, CORa, COORa, CONRaRb, etc; each of R4to R10 and R12 is alkyl, alkenyl or alkynyl; R11 is H, CORa, COORa, alkyl, alkenyl or alkynyl, or R11 and R12+N+C atoms to which they are attached may form a heterocyclic group; each of R13 and R14 is H, CORa, COORa, alkyl, alkenyl or alkynyl; each Ra and Rb is H, alkyl, alkenyl, alkynyl, etc.
    Type: Application
    Filed: December 16, 2021
    Publication date: June 2, 2022
    Inventors: Carmen CUEVAS MARCHANTE, Juan Manuel DOMINGUEZ CORREA, Andres FRANCESCH SOLLOSO, Maria GARRANZO GARCIA-IBARROLA, Maria Jose MUNOZ ALONSO, Francisco SANCHEZ MADRID, Juan Manuel ZAPATA HERNANDEZ, Alicia GARCIA ARROYO, Maria Angeles URSA PECHARROMAN
  • Patent number: 11224663
    Abstract: Drug conjugates of formula [D-(X)b-(AA)w-(L)-]n-Ab wherein: D is a drug moiety having the following formula (I) or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof, wherein: A is selected from (II) and (III) R1, R2 and R3 is H, ORa, OCORa, OCO—ORa, alkyl, alkenyl, alkynyl, etc.; R3? is, CORa, COORa, CONRaRb, etc; each of R4 to R10 and R12 is alkyl, alkenyl or alkynyl; R11 is H, CORa, COORa, alkyl, alkenyl or alkynyl, or R11 and R12+N+C atoms to which they are attached may form a heterocyclic group; each of R13 and R14 is H, CORa, COORa, alkyl, alkenyl or alkynyl; each Ra and Rb is H, alkyl, alkenyl, alkynyl, etc.
    Type: Grant
    Filed: June 2, 2014
    Date of Patent: January 18, 2022
    Assignee: PHARMA MAR, S.A.
    Inventors: Cármen Cuevas Marchante, Juan Manuel Domínguez Correa, Andrés Francesch Solloso, María Garranzo García-Ibarrola, María José Munoz Alonso, Francisco Sánchez Madrid, Juan Manuel Zapata Hernández, Alicia García Arroyo, Maria Ángeles Ursa Pecharromán
  • Patent number: 10005112
    Abstract: A method for lining an existing waste disposal site having a waste level includes, for example: installing perimeter barrier walls about the site and interior barrier walls within the perimeter barrier walls to define cells; transferring waste, such as for example ash, from one of the cells to one or more other cells to form an empty cell with a layer of contaminated material at the bottom of the empty cell; removing the layer of contaminated material from the empty cell to form a clean cell with a noncontaminated bottom layer; installing a barrier liner layer in the clean cell to form a lined cell; and transferring waste from other cells into the lined cell.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: June 26, 2018
    Assignee: ZAPATA INCORPORATED
    Inventor: Manuel Zapata
  • Publication number: 20170120314
    Abstract: A method for lining an existing waste disposal site having a waste level includes, for example: installing perimeter barrier walls about the site and interior barrier walls within the perimeter barrier walls to define cells; transferring waste, such as for example ash, from one of the cells to one or more other cells to form an empty cell with a layer of contaminated material at the bottom of the empty cell; removing the layer of contaminated material from the empty cell to form a clean cell with a noncontaminated bottom layer; installing a barrier liner layer in the clean cell to form a lined cell; and transferring waste from other cells into the lined cell.
    Type: Application
    Filed: October 28, 2016
    Publication date: May 4, 2017
    Applicant: Zapata Incorporated
    Inventor: Manuel Zapata
  • Publication number: 20160129128
    Abstract: Drug conjugates of formula [D-(X)b-(AA)w-(L)-]n-Ab wherein: D is a drug moiety having the following formula (I) or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof, wherein: A is selected from (II) and (III) R1, R2 and R3 is H, ORa, OCORa, OCO—ORa, alkyl, alkenyl, alkynyl, etc; R3? is, CORa, COORa, CONRaRb, etc; each of R4 to R10 and R12 is alkyl, alkenyl or alkynyl; R11 is H, CORa, COORa, alkyl, alkenyl or alkynyl, or R11 and R12+N+C atoms to which they are attached may form a heterocyclic group; each of R13 and R14 is H, CORa, COORa, alkyl, alkenyl or alkynyl; each Ra and Rb is H, alkyl, alkenyl, alkynyl, etc.
    Type: Application
    Filed: June 2, 2014
    Publication date: May 12, 2016
    Inventors: Cármen CUEVAS MARCHANTE, Juan Manuel DOMÍNGUEZ CORREA, Andrés FRANCESCH SOLLOSO, María GARRANZO GARCÍA-IBARROLA, María José MUNOZ ALONSO, Francisco SÁNCHEZ MADRID, Juan Manuel ZAPATA HERNÁNDEZ, Alicia GARCÍA ARROYO, Maria Ángeles URSA PECHARROMÁN
  • Patent number: 4898598
    Abstract: The present invention relates to a compound and method for polishing stone wherein the compound is a mixture of metallic oxides, a resin and a pre-prepared gel which compound is utilized in conjunction with sandpaper of varying grits to provide a smooth high-gloss finish to the cut, rough-edged stone or marble.
    Type: Grant
    Filed: October 27, 1988
    Date of Patent: February 6, 1990
    Assignee: Superior Granite & Marble Restoration
    Inventor: Manuel Zapata